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Showing 1–3 of 3 results
Advanced filters: Author: Mathieu Gendarme Clear advanced filters

  • Neufeldt et al. evaluate transcriptional and cytokine secretion profiles of cells and patient sera following SARS-CoV-2 infection and detect distinct upregulation of inflammatory cytokines. They also demonstrate that this upregulation is mediated by cGAS-STING and NF-κB signalling, which could provide a potential avenue for the development of future therapies against SARS-CoV-2.

    • Christopher J. Neufeldt
    • Berati Cerikan
    • Ralf Bartenschlager
    ResearchOpen Access
    Communications Biology
    Volume: 5, P: 1-15

  • Hamed Alborzinia et al. show that Golgi-dispersing compounds trigger iron-dependent oxidative degradation of lipids, inducing a non-apoptotic cell death called ferroptosis. This study provides insight into the role of Golgi apparatus for preventing ferroptotic cell death through its cellular redox control.

    • Hamed Alborzinia
    • Tatiana I. Ignashkova
    • Jan H. Reiling
    ResearchOpen Access
    Communications Biology
    Volume: 1, P: 1-15