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Showing 1–3 of 3 results
Advanced filters: Author: Maureane Hoffman Clear advanced filters

  • Bleeding complications limits the use of effective antithrombotics therapeutics. Here, the authors developed next-generation direct thrombin inhibitors with low bleeding risks as safe peri-percutaneous coronary intervention anticoagulants when used in combination with antiplatelets.

    • Cho Yeow Koh
    • Norrapat Shih
    • Mark Y. Chan
    ResearchOpen Access
    Nature Communications
    Volume: 12, P: 1-16

  • Trauma-induced coagulopathy describes alterations in haemostasis (such as fibrinogen depletion, inadequate thrombin generation, impaired platelet function and dysregulated fibrinolysis) that can result in both uncontrolled bleeding and hypercoagulation, leading to venous thromboembolism and multiple organ failure.

    • Ernest E. Moore
    • Hunter B. Moore
    • Angela Sauaia
    Reviews
    Nature Reviews Disease Primers
    Volume: 7, P: 1-23