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Advanced filters: Author: Megh Mehta Clear advanced filters
  • By characterizing APOB-reactive CD4+ T cells in patients with atherosclerosis, Roy et al. identify effector regulatory T (eTreg) cells as the predominant autoreactive subset. These APOB-specific eTreg cells are clonally expanded, express the plaque-homing receptor CXCR6 and progressively lose their regulatory phenotype as disease severity increases.

    • Payel Roy
    • Anusha Bellapu
    • Klaus Ley
    Research
    Nature Cardiovascular Research
    Volume: 4, P: 841-856