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Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia

Tumour cells can communicate with cells from distant organs through extracellular vesicles. Here the authors show that breast cancer cells derived exosomal miR-204-5p induce leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia.

Yong Hu
Liu Liu
Wei Yan
ResearchOpen Access24 Aug 2023
Nature Communications

Volume: 14, P: 1-20
Room-temperature continuous-wave electrically injected InGaN-based laser directly grown on Si

The fabrication of a blue–violet semiconductor laser on a silicon substrate enhances the integration of optoelectronics with electronics.

Yi Sun
Kun Zhou
Hui Yang
Research15 Aug 2016
Nature Photonics

Volume: 10, P: 595-599
Parkinson’s disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella

The Parkinson’s disease-associated leucine-rich repeat kinase 2 acts as a protein scaffold promoting mitochondria–Salmonella-containing vacuole tether formation and itaconate delivery to provide cell-intrinsic defence in Salmonella-infected macrophages.

Huan Lian
Donghyun Park
Jorge E. Galán
Research28 Aug 2023
Nature Microbiology

Volume: 8, P: 1880-1895
A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis

Jieruo Gu, Jianjun Liu and colleagues report the results of a genome-wide association study of ankylosing spondylitis in Han Chinese. They identify two new susceptibility loci for this inflammatory disease and confirm strong associations with variants in the HLA-B region.

Zhiming Lin
Jin-Xin Bei
Jieruo Gu
Research04 Dec 2011
Nature Genetics

Volume: 44, P: 73-77
On-wafer fabrication of cavity mirrors for InGaN-based laser diode grown on Si

Junlei He
Meixin Feng
Hui Yang
ResearchOpen Access21 May 2018
Scientific Reports

Volume: 8, P: 1-8
Correlation between thyroid hormone sensitivity and diabetic peripheral neuropathy in euthyroid patients with type 2 diabetes mellitus

Meixin Sun
Lu Yu
Guixia Wang
ResearchOpen Access23 Aug 2024
Scientific Reports

Volume: 14, P: 1-10
Process analysis and multi-parameter optimization of 5052 aluminum alloy FSW based on thermo-mechanical coupling and Taguchi method

Yuanpeng Liu
Meixin Ge
Weibing Wang
ResearchOpen Access02 Jan 2025
Scientific Reports

Volume: 15, P: 1-17
Room-temperature continuous-wave electrically pumped InGaN/GaN quantum well blue laser diode directly grown on Si

Yi Sun
Kun Zhou
Hui Yang
ResearchOpen Access13 Jun 2018
Light: Science & Applications

Volume: 7, P: 1-7
A wireless, implantable optoelectrochemical probe for optogenetic stimulation and dopamine detection

Changbo Liu
Yu Zhao
Xing Sheng
ResearchOpen Access24 Aug 2020
Microsystems & Nanoengineering

Volume: 6, P: 1-12
Lipid metabolism dysfunction induced by age-dependent DNA methylation accelerates aging

Xin Li
Jiaqiang Wang
Kang Zhang
ResearchOpen Access25 May 2022
Signal Transduction and Targeted Therapy

Volume: 7, P: 1-12
CRISPR/Cas9 therapeutics: progress and prospects

Tianxiang Li
Yanyan Yang
Tao Yu
ReviewsOpen Access16 Jan 2023
Signal Transduction and Targeted Therapy

Volume: 8, P: 1-23

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Cancer-cell-secreted miR-204-5p induces leptin signalling pathway in white adipose tissue to promote cancer-associated cachexia

Room-temperature continuous-wave electrically injected InGaN-based laser directly grown on Si

Parkinson’s disease kinase LRRK2 coordinates a cell-intrinsic itaconate-dependent defence pathway against intracellular Salmonella

A genome-wide association study in Han Chinese identifies new susceptibility loci for ankylosing spondylitis

On-wafer fabrication of cavity mirrors for InGaN-based laser diode grown on Si

Correlation between thyroid hormone sensitivity and diabetic peripheral neuropathy in euthyroid patients with type 2 diabetes mellitus

Process analysis and multi-parameter optimization of 5052 aluminum alloy FSW based on thermo-mechanical coupling and Taguchi method

Room-temperature continuous-wave electrically pumped InGaN/GaN quantum well blue laser diode directly grown on Si

A wireless, implantable optoelectrochemical probe for optogenetic stimulation and dopamine detection

Lipid metabolism dysfunction induced by age-dependent DNA methylation accelerates aging

CRISPR/Cas9 therapeutics: progress and prospects

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