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Acta Pharmacologica Sinica (4)
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Showing 1–7 of 7 results

Advanced filters: Author: Meng-Ru Zhang Clear advanced filters

Magnesium niobate as a high-κ gate dielectric for two-dimensional electronics

A high-κ dielectric ceramic, magnesium niobate, can be epitaxially grown on a mica substrate and then transferred to form the gate dielectric in molybdenum disulfide transistors, providing van der Waals interfaces and high robustness to temperature and voltage.

Cheng-Yi Zhu
Meng-Ru Zhang
Jing-Kai Qin
Research18 Sept 2024
Nature Electronics

Volume: 7, P: 1137-1146
A 5+1 assemble-to-activate mechanism of the Lon proteolytic machine

Many AAA+ (ATPases associated with diverse cellular activities) proteins function as a hexamer to remodel protein substrates. Here, the authors report the discovery of a pentameric form of the Lon AAA+ protease and show that it plays a role in the substrate-dependent activation of the AAA+ protein.

Shanshan Li
Kan-Yen Hsieh
Chung-I Chang
ResearchOpen Access13 Nov 2023
Nature Communications

Volume: 14, P: 1-13
P300-dependent acetylation of the FOXQ1 complex activates super-enhancers to promote colorectal cancer proliferation and metastasis

This study highlights FOXQ1 as a key regulator of super enhancers, contributing to a deeper comprehension of FOXQ1-related tumours and bolstering the notion that FOXQ1 could be a potential target for colorectal cancer treatment

Wen-Dong Yang
Zhi-Heng Zhang
Jin Bai
ResearchOpen Access07 Jul 2025
Communications Biology

Volume: 8, P: 1-14
Small molecule compound M12 reduces vascular permeability in obese mice via blocking endothelial TRPV4–Nox2 interaction

Meng-ru Gao
Peng Zhang
Xin Ma
Research15 Oct 2021
Acta Pharmacologica Sinica

Volume: 43, P: 1430-1440
Epac activation ameliorates tubulointerstitial inflammation in diabetic nephropathy

Wen-xia Yang
Yu Liu
Li Xiao
Research08 Jun 2021
Acta Pharmacologica Sinica

Volume: 43, P: 659-671
Novel Caspase-1 inhibitor CZL80 improves neurological function in mice after progressive ischemic stroke within a long therapeutic time-window

Ling Pan
Wei-dong Tang
Xiang-nan Zhang
Research02 May 2022
Acta Pharmacologica Sinica

Volume: 43, P: 2817-2827
Melatonin receptor agonist ramelteon attenuates mouse acute and chronic ischemic brain injury

Xiao-li Wu
Shou-sheng Lu
Xiang-nan Zhang
Research27 Feb 2020
Acta Pharmacologica Sinica

Volume: 41, P: 1016-1024