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Showing 201–250 of 259 results

Advanced filters: Author: Michael Comb Clear advanced filters

Combinatorial hydrogel library enables identification of materials that mitigate the foreign body response in primates

In vivo screening of a large combinatorial library of alginates identifies materials that elicit a substantially reduced foreign body response.

Arturo J Vegas
Omid Veiseh
Daniel G Anderson
Research25 Jan 2016
Nature Biotechnology

Volume: 34, P: 345-352
Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening

In this protocol, the authors describe CHyMErA (Cas hybrid for multiplexed editing and screening applications), a combinatorial genome-editing platform based on the co-expression of Cas9 and Cas12a nucleases in conjunction with a hybrid guide RNA.

Michael Aregger
Kun Xing
Thomas Gonatopoulos-Pournatzis
Protocols10 Sept 2021
Nature Protocols

Volume: 16, P: 4722-4765
SciPy 1.0: fundamental algorithms for scientific computing in Python

This Perspective describes the development and capabilities of SciPy 1.0, an open source scientific computing library for the Python programming language.

Pauli Virtanen
Ralf Gommers
Yoshiki Vázquez-Baeza
ReviewsOpen Access03 Feb 2020
Nature Methods

Volume: 17, P: 261-272
The ultrafast X-ray spectroscopic revolution in chemical dynamics

Ultrafast X-ray spectroscopies enable the investigation of fast chemical dynamics with time resolutions reaching the order of attoseconds. Processes such as spin crossover, structural deformations in excited states and dissociation reactions can now be studied through the use of short X-ray pulses produced by high-harmonic, free-electron-laser and synchrotron sources.

Peter M. Kraus
Michael Zürch
Stephen R. Leone
Reviews29 May 2018
Nature Reviews Chemistry

Volume: 2, P: 82-94
Instrumentation for the detection and characterization of exoplanets

Francesco Pepe
David Ehrenreich
Michael R. Meyer
Reviews17 Sept 2014
Nature

Volume: 513, P: 358-366
U24 from Roseolovirus interacts strongly with Nedd4 WW Domains

Yurou Sang
Rui Zhang
Suzana K. Straus
ResearchOpen Access04 Jan 2017
Scientific Reports

Volume: 7, P: 1-11
The pharmacoepigenomic landscape of cancer cell lines reveals the epigenetic component of drug sensitivity

A large-scale integrated analysis of differentially methylated sites, genetic, epigenetic, and transcriptomic datasets identifies epigenetic drug response biomarkers across multiple cancer types.

Alexander Joschua Ohnmacht
Anantharamanan Rajamani
Michael Patrick Menden
ResearchOpen Access09 Aug 2023
Communications Biology

Volume: 6, P: 1-11
Towards attosecond imaging at the nanoscale using broadband holography-assisted coherent imaging in the extreme ultraviolet

The inherently broad bandwidth of attosecond pulses conflicts with the coherence requirements of lensless imaging. Here, broadband holography-assisted coherent imaging is demonstrated with a resolution of less than 35 nm.

Wilhelm Eschen
Sici Wang
Jan Rothhardt
ResearchOpen Access07 Jul 2021
Communications Physics

Volume: 4, P: 1-7
Association between genetic variation in a region on chromosome 11 and schizophrenia in large samples from Europe

M Rietschel
M Mattheisen
S Cichon
Research12 Jul 2011
Molecular Psychiatry

Volume: 17, P: 906-917
Genetic Association of Recovery from Eating Disorders: The Role of GABA Receptor SNPs

Cinnamon S Bloss
Wade Berrettini
Walter H Kaye
Research13 Jul 2011
Neuropsychopharmacology

Volume: 36, P: 2222-2232
A proteomics approach to understanding protein ubiquitination

Junmin Peng
Daniel Schwartz
Steven P Gygi
Research20 Jul 2003
Nature Biotechnology

Volume: 21, P: 921-926
Brillouin integrated photonics

Acousto-optical interactions within integrated optics platforms are reviewed with a discussion of the useful chip-based devices such as lasers, amplifiers, filters, isolators and more besides that can result.

Benjamin J. Eggleton
Christopher G. Poulton
Gaurav Bahl
Reviews19 Aug 2019
Nature Photonics

Volume: 13, P: 664-677
Coral reef survival under accelerating ocean deoxygenation

Climate change and other human activities are decreasing ocean oxygen content. This Perspective considers the limited data on effects to coral reefs, including oxygen thresholds for lethal and sub-lethal effects in coral reef taxa, and proposes key research questions to address this critical issue.

David J. Hughes
Rachel Alderdice
David J. Suggett
Reviews31 Mar 2020
Nature Climate Change

Volume: 10, P: 296-307
Migratory management and environmental conditions affect lifespan and oxidative stress in honey bees

Michael Simone-Finstrom
Hongmei Li-Byarlay
David R. Tarpy
ResearchOpen Access24 Aug 2016
Scientific Reports

Volume: 6, P: 1-10
Genetic variation and pesticide exposure influence blood DNA methylation signatures in females with early-stage Parkinson’s disease

S. L. Schaffner
W. Casazza
M. S. Kobor
ResearchOpen Access07 May 2024
npj Parkinson's Disease

Volume: 10, P: 1-18
Ecological and evolutionary approaches to managing honeybee disease

Multiple interacting factors have contributed to the rapid decline of honeybee populations worldwide. Here, the authors review the impact of parasites and pathogens, and how ecological and evolutionary principles can guide management practices.

Berry J. Brosi
Keith S. Delaplane
Jacobus C. de Roode
Reviews22 Aug 2017
Nature Ecology & Evolution

Volume: 1, P: 1250-1262
Attenuation of genetic progress under continued selection in poultry

I Michael Lerner
Everett R Dempster
Research01 Apr 1951
Heredity

Volume: 5, P: 75-94
Immunoaffinity profiling of tyrosine phosphorylation in cancer cells

John Rush
Albrecht Moritz
Michael J Comb
Research01 Jan 2005
Nature Biotechnology

Volume: 23, P: 94-101
MetaGxData: Clinically Annotated Breast, Ovarian and Pancreatic Cancer Datasets and their Use in Generating a Multi-Cancer Gene Signature

Deena M. A. Gendoo
Michael Zon
Benjamin Haibe-Kains
ResearchOpen Access19 Jun 2019
Scientific Reports

Volume: 9, P: 1-14
A density threshold for the expression of longevity in Drosophila melanogaster

Leo S Luckinbill
Michael J Clare
Research01 Jun 1986
Heredity

Volume: 56, P: 329-335
High Speed Automated DNA Sequencing in Ultrathin Slab Gels

Anthony J. Kostichka
Michael L. Marchbanks
Lloyd M. Smith
Research01 Jan 1992
Bio/Technology

Volume: 10, P: 78-81
Methylomic and phenotypic analysis of the ModH5 phasevarion of Helicobacter pylori

Yogitha N. Srikhanta
Rebecca J. Gorrell
Terry Kwok
ResearchOpen Access23 Nov 2017
Scientific Reports

Volume: 7, P: 1-14
Single prokaryotic cell isolation and total transcript amplification protocol for transcriptomic analysis

This protocol enables amplification of the total transcript of a single prokaryotic cell for in-depth analysis. Laser-capture microdissection is used to isolate single cells, and amplified cDNA can be further analyzed by microarray.

Yun Kang
Ian McMillan
Tung T Hoang
Protocols04 Jun 2015
Nature Protocols

Volume: 10, P: 974-984
Mechanisms of transcriptional memory

Nicole J. Francis
Robert E. Kingston
Reviews01 Jun 2001
Nature Reviews Molecular Cell Biology

Volume: 2, P: 409-421
Neural network reactive force field for C, H, N, and O systems

Pilsun Yoo
Michael Sakano
Alejandro Strachan
ResearchOpen Access22 Jan 2021
npj Computational Materials

Volume: 7, P: 1-10
Detection of biological signals from a live mammalian muscle using an early stage diamond quantum sensor

James Luke Webb
Luca Troise
Ulrik Lund Andersen
ResearchOpen Access28 Jan 2021
Scientific Reports

Volume: 11, P: 1-11
Circulating pulse cavity enhancement as a method for extreme momentum transfer atom interferometry

Atom interferometry using single photon transitions has the potential to provide new tools for fundamental physics. This work proposes a circulating pulse scheme for enabling atom interferometry to operate in optical cavities without being constrained in their pulse bandwidth, providing a route to overcoming severe limitations in available laser power.

Rustin Nourshargh
Samuel Lellouch
Michael Holynski
ResearchOpen Access02 Dec 2021
Communications Physics

Volume: 4, P: 1-9
Unveiling the orbital texture of 1T-TiTe₂ using intrinsic linear dichroism in multidimensional photoemission spectroscopy

Samuel Beaulieu
Michael Schüler
Ralph Ernstorfer
ResearchOpen Access15 Nov 2021
npj Quantum Materials

Volume: 6, P: 1-11
The retinal toxicity profile towards assemblies of Amyloid-β indicate the predominant pathophysiological activity of oligomeric species

Efrat Naaman
Sarah Ya’ari
Shiri Zayit-Soudry
ResearchOpen Access01 Dec 2020
Scientific Reports

Volume: 10, P: 1-11
Functional genomics platform for pooled screening and generation of mammalian genetic interaction maps

This protocol describes an RNAi-based high-throughput screening strategy for determining genetic interactions between pairs of mammalian genes; the information obtained is then used to construct genetic interaction maps.

Martin Kampmann
Michael C Bassik
Jonathan S Weissman
Protocols03 Jul 2014
Nature Protocols

Volume: 9, P: 1825-1847
Bio-orthogonal labeling as a tool to visualize and identify newly synthesized proteins in Caenorhabditis elegans

The authors of this protocol describe an approach that enables distinguishing de novo–synthesized from pre-existing proteins in the model invertebrate Caenorhabditis elegans, as a way to determine the effect of internal and external stimuli.

Milena Ullrich
Vanessa Liang
Jürgen Götz
Protocols28 Aug 2014
Nature Protocols

Volume: 9, P: 2237-2255
Radiocarbon offsets and old world chronology as relevant to Mesopotamia, Egypt, Anatolia and Thera (Santorini)

Sturt W. Manning
Lukas Wacker
Willy Tegel
ResearchOpen Access17 Aug 2020
Scientific Reports

Volume: 10, P: 1-14
Improved HLA-based prediction of coeliac disease identifies two novel genetic interactions

Michael Erlichster
Justin Bedo
Benjamin Goudey
Research30 Jul 2020
European Journal of Human Genetics

Volume: 28, P: 1743-1752
Multi-time quantum correlations with no spatial analog

Martin Ringbauer
Fabio Costa
Alessandro Fedrizzi
ResearchOpen Access02 Aug 2018
npj Quantum Information

Volume: 4, P: 1-6
A kinome-wide RNAi screen identifies ALK as a target to sensitize neuroblastoma cells for HDAC8-inhibitor treatment

Jing Shen
Sara Najafi
Ina Oehme
ResearchOpen Access07 Mar 2018
Cell Death & Differentiation

Volume: 25, P: 2053-2070
Reconciling material cultures in archaeology with genetic data: The nomenclature of clusters emerging from archaeogenomic analysis

Stefanie Eisenmann
Eszter Bánffy
Philipp W. Stockhammer
ResearchOpen Access29 Aug 2018
Scientific Reports

Volume: 8, P: 1-12
Synchronous multi-color laser network with daily sub-femtosecond timing drift

Kemal Şafak
Ming Xin
Franz X. Kärtner
ResearchOpen Access09 Aug 2018
Scientific Reports

Volume: 8, P: 1-8
Neonicotinoids act like endocrine disrupting chemicals in newly-emerged bees and winter bees

Danica Baines
Emily Wilton
Nora Chomistek
ResearchOpen Access08 Sept 2017
Scientific Reports

Volume: 7, P: 1-18
High-throughput matrix screening identifies synergistic and antagonistic antimalarial drug combinations

Bryan T. Mott
Richard T. Eastman
Craig J. Thomas
ResearchOpen Access25 Sept 2015
Scientific Reports

Volume: 5, P: 1-14
Molecular logic behind the three-way stochastic choices that expand butterfly colour vision

Butterflies diversify their retinal mosaics by producing three stochastic types of ommatidia instead of the two types found in Drosophila; this study shows that butterfly retinas use two R7-like photoreceptors per ommatidium that each make an independent stochastic decision to express the transcription factor Spineless, which controls photoreceptor and ommatidial fate.

Michael Perry
Michiyo Kinoshita
Claude Desplan
Research06 Jul 2016
Nature

Volume: 535, P: 280-284
Honey bee queen health is unaffected by contact exposure to pesticides commonly found in beeswax

Alison McAfee
Joseph P Milone
David R Tarpy
ResearchOpen Access26 Jul 2021
Scientific Reports

Volume: 11, P: 1-12
Discriminating a common somatic ASXL1 mutation (c.1934dup; p.G646Wfs*12) from artifact in myeloid malignancies using NGS

Michael O. Alberti
Sridhar Nonavinkere Srivatsan
Matthew J. Walter
Research29 Jun 2018
Leukemia

Volume: 32, P: 1874-1878
Percutaneous Closure of Left Atrial Appendage significantly affects Lipidome Metabolism

G. Yücel
M. Behnes
I. Akin
ResearchOpen Access12 Apr 2018
Scientific Reports

Volume: 8, P: 1-13
Attosecond precision multi-kilometer laser-microwave network

Ming Xin
Kemal Şafak
Franz X Kärtner
ResearchOpen Access11 Jul 2016
Light: Science & Applications

Volume: 6, P: e16187
Odorant cues linked to social immunity induce lateralized antenna stimulation in honey bees (Apis mellifera L.)

Alison McAfee
Troy F. Collins
Leonard J. Foster
ResearchOpen Access07 Apr 2017
Scientific Reports

Volume: 7, P: 1-12
Nitrotoga-like bacteria are previously unrecognized key nitrite oxidizers in full-scale wastewater treatment plants

Sebastian Lücker
Jasmin Schwarz
Holger Daims
Research02 Sept 2014
The ISME Journal

Volume: 9, P: 708-720
Biochemical detection of alien DNA incorporated into wheat by chromosome engineering

Richard Flavell
Michael O'Dell
Derek Smith
Research01 Jun 1978
Heredity

Volume: 40, P: 439-455
Pathways of Serine and Glycine Metabolism in Primary Culture of Ovine Fetal Hepatocytes

Patti J Thureen
Michael R Narkewicz
Paul V Fennessey
Research01 Nov 1995
Pediatric Research

Volume: 38, P: 775-782
New African species in the Drosophila obscura species group: genetic variation, differentiation and evolution

Marie Louise Cariou
Daniel Lachaise
Michael Ashburner
Research01 Aug 1988
Heredity

Volume: 61, P: 73-84
Book reviews

Michael Lawrence
Books & Arts01 Apr 1993
Heredity

Volume: 70, P: 444-445

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