Nature Search

Modeling response to the KRAS-G12C inhibitor AZD4625 in KRAS^G12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms

Joshua C. Rosen
Pinjiang Cao
Ming-Sound Tsao
ResearchOpen Access11 Oct 2025
British Journal of Cancer

P: 1-10
Surgical illustrative review of the treatment of ischaemic priapism

Margaret Gannon
Aaron Krug
Omer Raheem
ReviewsOpen Access29 Mar 2025
International Journal of Impotence Research

P: 1-6
Characterization of a cancer cachectic factor

Penio Todorov
Peter Cariuk
Michael Tisdale
Research22 Feb 1996
Nature

Volume: 379, P: 739-742
Phenotypic variability of inbred and outbred mice

MICHAEL F. W. FESTING
Research01 Sept 1976
Nature

Volume: 263, P: 230-232
Harnessing speckle for a sub-femtometre resolved broadband wavemeter and laser stabilization

The complex speckle pattern produced by coherent multiple scattering contains information about the incident light field, which has recently been used for imaging. Metzgeret al. use speckle to construct a wavemeter with sub-femtometre resolution which is subsequently used for laser stabilization.

Nikolaus Klaus Metzger
Roman Spesyvtsev
Kishan Dholakia
ResearchOpen Access05 Jun 2017
Nature Communications

Volume: 8, P: 1-8
CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Alterations in the tumour suppressor genes STK11 and/or KEAP1 can identify patients with advanced non-small-cell lung cancer who are likely to benefit from combinations of PD-(L)1 and CTLA4 immune checkpoint inhibitors added to chemotherapy.

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
ResearchOpen Access09 Oct 2024
Nature

Volume: 635, P: 462-471
Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Ferdinandos Skoulidis
Haniel A. Araujo
John V. Heymach
Amendments and CorrectionsOpen Access27 Feb 2025
Nature

Volume: 639, P: E19
Enhanced two-photon excited fluorescence from imaging agents using true thermal light

Excitation with thermal light from a superluminescent diode is shown to yield enhanced fluorescence from both quantum dots and dyes, potentially enabling higher-sensitivity biological imaging.

Andreas Jechow
Michael Seefeldt
Ralf Menzel
Research06 Oct 2013
Nature Photonics

Volume: 7, P: 973-976
Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP

Yeon-Gil Kim
Eun Ju Sohn
Byung-Ha Oh
Research19 Dec 2004
Nature Structural & Molecular Biology

Volume: 12, P: 38-45
The Smc5–Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus

Jordi Torres-Rosell
Ivana Sunjevaric
Michael Lisby
Research22 Jul 2007
Nature Cell Biology

Volume: 9, P: 923-931
Stress-System Genes and Life Stress Predict Cortisol Levels and Amygdala and Hippocampal Volumes in Children

David Pagliaccio
Joan L Luby
Deanna M Barch
Research25 Nov 2013
Neuropsychopharmacology

Volume: 39, P: 1245-1253
A drug discovery platform to identify compounds that inhibit EGFR triple mutants

A high-throughput small-molecule drug screening platform enabled the detection of compounds targeting the functional interactions of receptor tyrosine kinases and identifies four new EGFR triple-mutant inhibitors.

Punit Saraon
Jamie Snider
Igor Stagljar
Research24 Feb 2020
Nature Chemical Biology

Volume: 16, P: 577-586
Characterization of three TRAPPC11 variants suggests a critical role for the extreme carboxy terminus of the protein

Miroslav P. Milev
Daniela Stanga
Cecilia Jimenez-Mallebrera
ResearchOpen Access01 Oct 2019
Scientific Reports

Volume: 9, P: 1-15
Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis

Colitis is one of the most common immune-related adverse events in patients with cancer treated with immune checkpoint inhibitors. Here the authors show that a polygenic risk score for ulcerative colitis can predict immune checkpoint inhibitor-mediated colitis in patients with cancer.

Pooja Middha
Rohit Thummalapalli
Elad Ziv
ResearchOpen Access26 Mar 2024
Nature Communications

Volume: 15, P: 1-10
Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Julien Barc
Rafik Tadros
Connie R. Bezzina
Amendments and Corrections26 Apr 2022
Nature Genetics

Volume: 54, P: 735
Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Genome-wide association analyses identify new susceptibility loci for Brugada syndrome. Functional studies implicate microtubule-related trafficking effects on sodium channel expression as an underlying molecular mechanism.

Julien Barc
Rafik Tadros
Connie R. Bezzina
Research24 Feb 2022
Nature Genetics

Volume: 54, P: 232-239
Larval regulation of adult longevity in a genetically-selected long-lived strain of Drosophila

Steven Buck
Michael Nicholson
Robert Arking
Research01 Jul 1993
Heredity

Volume: 71, P: 23-32
Implantable silicon neural probes with nanophotonic phased arrays for single-lobe beam steering

When mapping brain activity with optogenetic techniques, patterned illumination is critical for targeted stimulation. Here, implantable silicon neural probes forming a single steerable beam are developed and in vivo demonstrations reported the device’s potential for deep brain optogenetic stimulation

Fu-Der Chen
Ankita Sharma
Joyce K. S. Poon
ResearchOpen Access18 Dec 2024
Communications Engineering

Volume: 3, P: 1-12
Publisher Correction: Characterization of three TRAPPC11 variants suggests a critical role for the extreme carboxy terminus of the protein

Miroslav P. Milev
Daniela Stanga
Cecilia Jimenez-Mallebrera
Amendments and CorrectionsOpen Access10 Nov 2020
Scientific Reports

Volume: 10, P: 1
3D printed titanium carbide MXene-coated polycaprolactone scaffolds for guided neuronal growth and photothermal stimulation

Neural circuitry is important for comprehending computational mechanisms and physiology of the brain but controlling neuronal connectivity and response in 3D is challenging. Here, titanium carbide MXene-coated 3D polycaprolactone scaffolds are demonstrated to effectively control neuronal interconnection.

Jianfeng Li
Payam Hashemi
Joyce K. S. Poon
ResearchOpen Access24 Apr 2024
Communications Materials

Volume: 5, P: 1-12
Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

Roddy Walsh
Najim Lahrouchi
Connie R. Bezzina
ResearchOpen Access07 Sept 2020
Genetics in Medicine

Volume: 23, P: 47-58
A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults

Anahit Babayan
Miray Erbey
Arno Villringer
ResearchOpen Access12 Feb 2019
Scientific Data

Volume: 6, P: 1-21
High SARS-CoV-2 seroprevalence in children and adults in the Austrian ski resort of Ischgl

Knabl et al. perform a seroepidemiological study in the Austrian ski resort Ischgl, where a super-spreader event lead to a SARS-CoV-2 outbreak. Through mathematical modelling, they find that the subsequent decline in viral transmission was most likely a combined effect of high seropositivity and the implementation of non-pharmaceutical interventions.

Ludwig Knabl
Tanmay Mitra
Dorothee von Laer
ResearchOpen Access30 Jun 2021
Communications Medicine

Volume: 1, P: 1-9

Search

Modeling response to the KRAS-G12C inhibitor AZD4625 in KRAS^G12C NSCLC patient-derived xenografts reveals insights into primary resistance mechanisms

Surgical illustrative review of the treatment of ischaemic priapism

Characterization of a cancer cachectic factor

Phenotypic variability of inbred and outbred mice

Harnessing speckle for a sub-femtometre resolved broadband wavemeter and laser stabilization

CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Author Correction: CTLA4 blockade abrogates KEAP1/STK11-related resistance to PD-(L)1 inhibitors

Enhanced two-photon excited fluorescence from imaging agents using true thermal light

Crystal structure of bet3 reveals a novel mechanism for Golgi localization of tethering factor TRAPP

The Smc5–Smc6 complex and SUMO modification of Rad52 regulates recombinational repair at the ribosomal gene locus

Stress-System Genes and Life Stress Predict Cortisol Levels and Amygdala and Hippocampal Volumes in Children

A drug discovery platform to identify compounds that inhibit EGFR triple mutants

Characterization of three TRAPPC11 variants suggests a critical role for the extreme carboxy terminus of the protein

Polygenic risk score for ulcerative colitis predicts immune checkpoint inhibitor-mediated colitis

Author Correction: Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Genome-wide association analyses identify new Brugada syndrome risk loci and highlight a new mechanism of sodium channel regulation in disease susceptibility

Larval regulation of adult longevity in a genetically-selected long-lived strain of Drosophila

Implantable silicon neural probes with nanophotonic phased arrays for single-lobe beam steering

Publisher Correction: Characterization of three TRAPPC11 variants suggests a critical role for the extreme carboxy terminus of the protein

3D printed titanium carbide MXene-coated polycaprolactone scaffolds for guided neuronal growth and photothermal stimulation

Enhancing rare variant interpretation in inherited arrhythmias through quantitative analysis of consortium disease cohorts and population controls

A mind-brain-body dataset of MRI, EEG, cognition, emotion, and peripheral physiology in young and old adults

High SARS-CoV-2 seroprevalence in children and adults in the Austrian ski resort of Ischgl

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