Nature Search

Genome-wide functional analysis of pathogenicity genes in the rice blast fungus

Junhyun Jeon
Sook-Young Park
Yong-Hwan Lee
Research11 Mar 2007
Nature Genetics

Volume: 39, P: 561-565
RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans

The decline of DNA and protein quality control contributes to organismal ageing. Here, Sonet al. report that nonsense-mediated mRNA decay, a RNA quality control mechanism, is enhanced in long-lived daf-2 mutant worms and contributes to their longevity by regulating expression of the yars-2/tyrosyl tRNA synthetase.

Heehwa G. Son
Mihwa Seo
Seung-Jae V. Lee
ResearchOpen Access09 Mar 2017
Nature Communications

Volume: 8, P: 1-11
Longitudinal pharmacogenomic analysis of refractory lung cancer to identify therapeutic candidates for epidermal growth factor receptor–tyrosine kinase inhibitor resistance subclones

Namhee Yu
Mihwa Hwang
Ji-Youn Han
ResearchOpen Access04 Jul 2025
Experimental & Molecular Medicine

Volume: 57, P: 1567-1578
Overexpression of TC-PTP in murine epidermis attenuates skin tumor formation

Mihwa Kim
Liza D. Morales
Dae Joon Kim
Research14 Apr 2020
Oncogene

Volume: 39, P: 4241-4256
Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development

Hyunseung Lee
Mihwa Kim
Dae Joon Kim
ResearchOpen Access21 Mar 2017
Scientific Reports

Volume: 7, P: 1-15
Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling

Minwoo Baek
Mihwa Kim
Dae Joon Kim
ResearchOpen Access28 Jun 2018
Cell Death & Disease

Volume: 9, P: 1-15
Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening

Christine Garcia and colleagues use exome sequencing to identify genetic risk factors for familial pulmonary fibrosis. They observe an excess of rare damaging variants in PARN and RTEL1 in probands with pulmonary fibrosis and show that these variants cosegregate with disease in the affected families.

Bridget D Stuart
Jungmin Choi
Christine Kim Garcia
Research13 Apr 2015
Nature Genetics

Volume: 47, P: 512-517
Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy

Sang Won Park
Sean WC Chen
H Thomas Lee
Research09 Aug 2010
Laboratory Investigation

Volume: 91, P: 63-84
Selective intrarenal human A₁ adenosine receptor overexpression reduces acute liver and kidney injury after hepatic ischemia reperfusion in mice

Sang Won Park
Sean W C Chen
H Thomas Lee
Research11 Jan 2010
Laboratory Investigation

Volume: 90, P: 476-495
Acute kidney injury after hepatic ischemia and reperfusion injury in mice

H Thomas Lee
Sang W Park
Vivette D D'Agati
Research15 Dec 2008
Laboratory Investigation

Volume: 89, P: 196-208
Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P₁ receptor activation

Sang Won Park
Mihwa Kim
H Thomas Lee
Research10 May 2010
Laboratory Investigation

Volume: 90, P: 1209-1224

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Genome-wide functional analysis of pathogenicity genes in the rice blast fungus

RNA surveillance via nonsense-mediated mRNA decay is crucial for longevity in daf-2/insulin/IGF-1 mutant C. elegans

Longitudinal pharmacogenomic analysis of refractory lung cancer to identify therapeutic candidates for epidermal growth factor receptor–tyrosine kinase inhibitor resistance subclones

Overexpression of TC-PTP in murine epidermis attenuates skin tumor formation

Targeted disruption of TC-PTP in the proliferative compartment augments STAT3 and AKT signaling and skin tumor development

Epidermal-specific deletion of TC-PTP promotes UVB-induced epidermal cell survival through the regulation of Flk-1/JNK signaling

Exome sequencing links mutations in PARN and RTEL1 with familial pulmonary fibrosis and telomere shortening

Cytokines induce small intestine and liver injury after renal ischemia or nephrectomy

Selective intrarenal human A₁ adenosine receptor overexpression reduces acute liver and kidney injury after hepatic ischemia reperfusion in mice

Acute kidney injury after hepatic ischemia and reperfusion injury in mice

Sphinganine-1-phosphate protects kidney and liver after hepatic ischemia and reperfusion in mice through S1P₁ receptor activation

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