Nature Search

Mitochondrial components secretion in extracellular vesicles promotes alveolar epithelial mitochondrial quality control

The authors provide evidence of the secretion of mitochondrial components in extracellular vesicles dependent on GPRC5A as a pathway of mitochondrial quality control in AEC2s, which is essential for lung homeostasis maintenance.

Bowen Liu
Yue Han
Yuxin Yin
ResearchOpen Access05 Dec 2025
Nature Communications

Volume: 17, P: 1-17
Zinc accumulation-induced integrated stress response triggers β-cell identity loss

Qing Ma
Wenjun Xu
Weida Li
ResearchOpen Access28 Jan 2026
Cell Research

P: 1-18
Cell surface patching via CXCR4-targeted nanothreads for cancer metastasis inhibition

CXCR4-targeted therapies have been proposed for the treatment of cancer metastasis. Here the authors propose a CXCR4-targeted strategy based on interactable polymer nanothreads, showing inhibition of metastasis in preclinical cancer models.

Minglu Zhou
Chendong Liu
Lian Li
ResearchOpen Access29 Mar 2024
Nature Communications

Volume: 15, P: 1-21
The effectiveness of child policies to boost child quality and quantity in the PAYG pension system

Minglu Wang
Peng Jing
Xi Lin
ResearchOpen Access03 Mar 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-12
GHS-R1a signaling drives anxiety-related behavior by shaping excitability of ventromedial hypothalamic neurons

The neural substrates of anxiety are poorly understood. Here authors show that VMH αCaMKII⁺ neurons reduce anxiety when stressed. Ghrelin receptor GHS-R1a inhibits these neurons, promoting anxiety. Targeting GHS-R1a may help treat anxiety disorders.

Meng Zhang
Liu Yang
Yu Zhou
ResearchOpen Access24 Apr 2025
Nature Communications

Volume: 16, P: 1-16
A chromosome-level genome assembly of Cydia pomonella provides insights into chemical ecology and insecticide resistance

The codling moth, Cydia pomonella, is one of the major pests of pome fruit (apples and pears) and walnuts. Here, the authors sequence and analyze its genome, providing insights on olfactory and detoxification processes that may underlie its worldwide expansion.

Fanghao Wan
Chuanlin Yin
Fei Li
ResearchOpen Access17 Sept 2019
Nature Communications

Volume: 10, P: 1-14
Size-Dependent Melting Behavior of Colloidal In, Sn and Bi Nanocrystals

Minglu Liu
Robert Y. Wang
ResearchOpen Access17 Nov 2015
Scientific Reports

Volume: 5, P: 1-9
Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder

Huarong Yang
Di Liu
Jingyun Yang
ResearchOpen Access17 Apr 2021
Translational Psychiatry

Volume: 11, P: 1-9
ZnT8 loss-of-function accelerates functional maturation of hESC-derived β cells and resists metabolic stress in diabetes

Immature function and fragility hinder application of hESC-derived β cells (SC-β cell) for diabetes cell therapy. Here, the authors identify ZnT8 as a gene editing target to enhance the insulin secretion and cell survival under metabolic stress by abolishing zinc transport in SC-β cells.

Qing Ma
Yini Xiao
Weida Li
ResearchOpen Access16 Jul 2022
Nature Communications

Volume: 13, P: 1-16
Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

Tolerant T cells display characteristic patterns of gene expression and epigenetics that are distinct from other types of T cells and are orchestrated by the transcription factor NR4A1.

Xindong Liu
Yun Wang
Chen Dong
Research27 Feb 2019
Nature

Volume: 567, P: 525-529
From opportunity to inequality: how the rural digital economy shapes intra-rural income distribution

Hanjie Wang
Hao Leng
Minglu Yuan
ResearchOpen Access15 Apr 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-14
A preliminary exploration of establishing a mice model of hypoxic training

Minglu Li
Zhijie Chen
Jiaxing Zhang
ResearchOpen Access04 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Carbonate radical ion as a key driver of rapid atmospheric sulfate formation

Yangyang Liu
Xiao Li
Liwu Zhang
ResearchOpen Access12 Feb 2025
npj Climate and Atmospheric Science

Volume: 8, P: 1-12
Construction and application of a knowledge graph-based question answering system for Nanjing Yunjin digital resources

Liang Xu
Lu Lu
Minglu Liu
ResearchOpen Access19 Oct 2023
Heritage Science

Volume: 11, P: 1-17
Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells

Large tumors induce anemia and expansion of CD45⁺ immature erythroid cells, which represent a major immunosuppressive population in the spleen, contributing to systemic suppression of T cell immunity in late-stage cancer.

Lintao Zhao
Ran He
Bo Zhu
Research08 Oct 2018
Nature Medicine

Volume: 24, P: 1536-1544
Nanjing Yunjin intelligent question-answering system based on knowledge graphs and retrieval augmented generation technology

Liang Xu
Lu Lu
Lizhen Wu
ResearchOpen Access09 Apr 2024
Heritage Science

Volume: 12, P: 1-23
Transdermal protein delivery by a coadministered peptide identified via phage display

Yongping Chen
Yuanyuan Shen
Long-Ping Wen
Research26 Mar 2006
Nature Biotechnology

Volume: 24, P: 455-460
Spectrum-efficient user grouping and resource allocation based on deep reinforcement learning for mmWave massive MIMO-NOMA systems

Minghao Wang
Xin Liu
Minglu Jin
ResearchOpen Access17 Apr 2024
Scientific Reports

Volume: 14, P: 1-18
The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection

Xiangyu Chen
Guoshuai Cao
Lilin Ye
ResearchOpen Access06 Mar 2019
Cellular & Molecular Immunology

Volume: 17, P: 247-260
An epidermal sEMG tattoo-like patch as a new human–machine interface for patients with loss of voice

Huicong Liu
Wei Dong
Chengkuo Lee
ResearchOpen Access09 Mar 2020
Microsystems & Nanoengineering

Volume: 6, P: 1-13
Efficient control of chronic LCMV infection by a CD4 T cell epitope-based heterologous prime-boost vaccination in a murine model

Ran He
Xinxin Yang
Lilin Ye
Research13 Mar 2017
Cellular & Molecular Immunology

Volume: 15, P: 815-826
PTEN regulates RPA1 and protects DNA replication forks

Guangxi Wang
Yang Li
Yuxin Yin
Research25 Sept 2015
Cell Research

Volume: 25, P: 1189-1204

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Mitochondrial components secretion in extracellular vesicles promotes alveolar epithelial mitochondrial quality control

Zinc accumulation-induced integrated stress response triggers β-cell identity loss

Cell surface patching via CXCR4-targeted nanothreads for cancer metastasis inhibition

The effectiveness of child policies to boost child quality and quantity in the PAYG pension system

GHS-R1a signaling drives anxiety-related behavior by shaping excitability of ventromedial hypothalamic neurons

A chromosome-level genome assembly of Cydia pomonella provides insights into chemical ecology and insecticide resistance

Size-Dependent Melting Behavior of Colloidal In, Sn and Bi Nanocrystals

Mendelian randomization integrating GWAS and eQTL data revealed genes pleiotropically associated with major depressive disorder

ZnT8 loss-of-function accelerates functional maturation of hESC-derived β cells and resists metabolic stress in diabetes

Genome-wide analysis identifies NR4A1 as a key mediator of T cell dysfunction

From opportunity to inequality: how the rural digital economy shapes intra-rural income distribution

A preliminary exploration of establishing a mice model of hypoxic training

Carbonate radical ion as a key driver of rapid atmospheric sulfate formation

Construction and application of a knowledge graph-based question answering system for Nanjing Yunjin digital resources

Late-stage tumors induce anemia and immunosuppressive extramedullary erythroid progenitor cells

Nanjing Yunjin intelligent question-answering system based on knowledge graphs and retrieval augmented generation technology

Transdermal protein delivery by a coadministered peptide identified via phage display

Spectrum-efficient user grouping and resource allocation based on deep reinforcement learning for mmWave massive MIMO-NOMA systems

The histone methyltransferase EZH2 primes the early differentiation of follicular helper T cells during acute viral infection

An epidermal sEMG tattoo-like patch as a new human–machine interface for patients with loss of voice

Efficient control of chronic LCMV infection by a CD4 T cell epitope-based heterologous prime-boost vaccination in a murine model

PTEN regulates RPA1 and protects DNA replication forks

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