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Multimodal fusion of radio-pathology and proteogenomics identify integrated glioma subtypes with prognostic and therapeutic opportunities

Glioma is a complex disease, and prognosis can depend on clinical, genomic and radiological information. Here, the authors develop a multimodal fusion subtyping model to integrate data modalities for predicting glioma subtypes.

Zaoqu Liu
Yushuai Wu
Zhenyu Zhang
ResearchOpen Access13 Apr 2025
Nature Communications

Volume: 16, P: 1-18
Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images

Determining glioma types directly from whole-slide images (WSIs) would be of great diagnostic utility. Here, the authors develop a deep learning model to identify diffuse glioma types from WSIs according to the 2021 WHO classification across multiple cohorts and with interpretable features.

Weiwei Wang
Yuanshen Zhao
Zhenyu Zhang
ResearchOpen Access11 Oct 2023
Nature Communications

Volume: 14, P: 1-11
Reversible hydrogen spillover in Ru-WO_3-x enhances hydrogen evolution activity in neutral pH water splitting

While water splitting electrolysis offers an appealing means to produce H₂ fuel, catalysts show sluggish reaction rate in neutral media. Here, authors utilize hydrogen spillover from oxygen-deficient tungsten oxides to Ru nanoparticles to boost the neutral-pH H₂ evolution performances.

Jiadong Chen
Chunhong Chen
Yong Wang
ResearchOpen Access14 Sept 2022
Nature Communications

Volume: 13, P: 1-10
Effects of reflecting water on viewers’ visual attention, spatial perception, and emotional responses: a case study in Chinese heritage garden

Minkai Sun
Yanyan Bao
ResearchOpen Access22 Feb 2025
npj Heritage Science

Volume: 13, P: 1-11
Differential microbial assemblages associated with shikonin-producing Borage species in two distinct soil types

Aliya Fazal
Minkai Yang
Yonghua Yang
ResearchOpen Access24 May 2021
Scientific Reports

Volume: 11, P: 1-12
Targeting necrotic lipid release in tumors enhances immunosurveillance and cancer immunotherapy of glioblastoma

Yapeng Ji
Junyao Jiang
Hongtao Yu
Research03 Sept 2025
Cell Research

Volume: 35, P: 859-875
Prediction of blood supply in vestibular schwannomas using radiomics machine learning classifiers

Dixiang Song
Yixuan Zhai
Xinting Wei
ResearchOpen Access23 Sept 2021
Scientific Reports

Volume: 11, P: 1-9

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Multimodal fusion of radio-pathology and proteogenomics identify integrated glioma subtypes with prognostic and therapeutic opportunities

Neuropathologist-level integrated classification of adult-type diffuse gliomas using deep learning from whole-slide pathological images

Reversible hydrogen spillover in Ru-WO3-x enhances hydrogen evolution activity in neutral pH water splitting

Effects of reflecting water on viewers’ visual attention, spatial perception, and emotional responses: a case study in Chinese heritage garden

Differential microbial assemblages associated with shikonin-producing Borage species in two distinct soil types

Targeting necrotic lipid release in tumors enhances immunosurveillance and cancer immunotherapy of glioblastoma

Prediction of blood supply in vestibular schwannomas using radiomics machine learning classifiers

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Reversible hydrogen spillover in Ru-WO_3-x enhances hydrogen evolution activity in neutral pH water splitting