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Showing 1–6 of 6 results

Advanced filters: Author: Mohibullah Shah Clear advanced filters

Tracking clonal evolution during treatment in ovarian cancer using cell-free DNA

A combined sequencing technique assesses 18 patients with high-grade serous ovarian cancer over a multi-year period from diagnosis to recurrence and shows drug resistance typically arises from selective expansion of one or a few clones present at diagnosis.

Marc J. Williams
Ignacio Vázquez-García
Sohrab P. Shah
ResearchOpen Access01 Oct 2025
Nature

P: 1-9
Computer-aided screening of marine fungal metabolites as potential inhibitors of new Delhi metallo-beta-lactamase-1

Farhat Shabbir
Vipin Kumar Mishra
Ke Chen
ResearchOpen Access30 Sept 2025
Scientific Reports

Volume: 15, P: 1-24
Ongoing genome doubling shapes evolvability and immunity in ovarian cancer

A single-cell sequencing study using more than 30,000 tumour genomes from human ovarian cancers shows that whole-genome doubling is an ongoing mutational process that drives tumour evolution and disrupts immunity.

Andrew McPherson
Ignacio Vázquez-García
Sohrab P. Shah
ResearchOpen Access16 Jul 2025
Nature

Volume: 644, P: 1078-1087
Computational design of an mRNA vaccine targeting antifungal-resistant Lomentospora prolificans

Muhammad Bilal Iqbal Rehmani
Fizza Arshad
Mohibullah Shah
ResearchOpen Access01 Oct 2025
Scientific Reports

Volume: 15, P: 1-24
Ovarian cancer mutational processes drive site-specific immune evasion

Multi-modal analysis of genomically unstable ovarian tumours characterizes the contribution of anatomical sites and mutational processes to evolutionary phenotypic divergence and immune resistance mechanisms.

Ignacio Vázquez-García
Florian Uhlitz
Sohrab P. Shah
ResearchOpen Access14 Dec 2022
Nature

Volume: 612, P: 778-786
Core-genome guided novel therapeutic targets identification and chimeric vaccine designing against Rickettsia rickettsii

Fizza Arshad
Asifa Sarfraz
Mohibullah Shah
ResearchOpen Access06 Jan 2025
Scientific Reports

Volume: 15, P: 1-25