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Showing 1–2 of 2 results
Advanced filters: Author: Mohita Tagore Clear advanced filters

  • In cutaneous melanoma, desmosome genes are frequently affected by coding mutations that decrease their expression. This decrease in expression occurs predominantly in keratinocytes in the tumor microenvironment and can induce hyperproliferation of adjacent melanoma cells in coculture.

    • Maayan Baron
    • Mohita Tagore
    • Trey Ideker
    Research
    Nature Genetics
    Volume: 57, P: 1179-1188

  • In a zebrafish model of human cutaneous and acral melanomas, CRKL amplification causes tumours to favour a fin location, indicating that tumour location is determined by both the driver oncogenes and the pre-existing positional identity gene program.

    • Joshua M. Weiss
    • Miranda V. Hunter
    • Richard M. White
    Research
    Nature
    Volume: 604, P: 354-361