TASK-1 and -3 are members of the two-pore domain K+ channel family that play important roles in the regulation of cellular excitability. Here, Wilke et al.demonstrate that the second messenger lipid diacylglycerol (DAG) gates TASK1/3, defining a new role for DAG in controlling the dynamics of cellular excitability.
- Bettina U. Wilke
- Moritz Lindner
- Dominik Oliver
