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Showing 51–62 of 62 results
Advanced filters: Author: Mu-Ming Poo Clear advanced filters
  • Hippocampal GABAergic synapses are excitatory during the early postnatal period and can undergo spike timing-dependent modifications of synaptic strength. Xu and colleagues demonstrate that this plasticity can be modulated bidirectionally by frequency and that it depends on the action of GABAB receptors.

    • Chun Xu
    • Man-xia Zhao
    • Xiao-hui Zhang
    Research
    Nature Neuroscience
    Volume: 11, P: 1410-1418
  • The neurotrophins were named after their ability to regulate the survival and differentiation of nerve cells. But they are also thought to be involved in the processes that underlie neuronal plasticity, and a new report indicates that their function goes even further than this -- they not only modulate chemical transmission, but, like the more classical neurotransmitters, they mediate it.

    • Benedikt Berninger
    • Mu-ming Poo
    News & Views
    Nature
    Volume: 401, P: 862-863
  • The authors uncovered a pathway from the lateral amygdala to the auditory cortex (ACx) of mice that is essential for auditory fear memory retrieval. Simultaneous imaging of pre- and postsynaptic structures in ACx in vivo revealed an increased rate of synapse formation in this pathway after auditory fear conditioning.

    • Yang Yang
    • Dan-qian Liu
    • Mu-ming Poo
    Research
    Nature Neuroscience
    Volume: 19, P: 1348-1355
  • A consortium of researchers, advocates and clinicians announces here research priorities for improving the lives of people with mental illness around the world, and calls for urgent action and investment.

    • Pamela Y. Collins
    • Vikram Patel
    • Mark Walport
    Comments & Opinion
    Nature
    Volume: 475, P: 27-30
  • In the adult brain, neurogenesis occurs in a few restricted niches. However, the activation of glia following brain injury can endow these cells with stem cell properties. Götz and colleagues discuss how a more detailed knowledge of reactive gliosis might enable the stem cell potential of glia to be harnessed.

    • Stefanie Robel
    • Benedikt Berninger
    • Magdalena Götz
    Reviews
    Nature Reviews Neuroscience
    Volume: 12, P: 88-104
  • The growth cones of developing axons are guided towards their targets by gradients of cues. Kamiguchi and colleagues propose a mechanism for this process whereby cues trigger an alteration in the balance of endocytosis and exocytosis on one side of the growth cone, biasing the direction of turning.

    • Takuro Tojima
    • Jacob H. Hines
    • Hiroyuki Kamiguchi
    Reviews
    Nature Reviews Neuroscience
    Volume: 12, P: 191-203
  • Calcium signals have profound and varied effects on growth cone motility and growth. Gomez and Zheng review recent evidence on intracellular calcium signalling pathways, providing fresh insight into how this 'simple' ion can have diverse effects on growth cone behaviours.

    • Timothy M. Gomez
    • James Q. Zheng
    Reviews
    Nature Reviews Neuroscience
    Volume: 7, P: 115-125