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Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Geospatial estimates of the prevalence of anemia in women of reproductive age across 82 low-income and middle-income countries reveals considerable heterogeneity and inequality at national and subnational levels, with few countries on track to meet the WHO Global Nutrition Targets by 2030.

Damaris Kinyoki
Aaron E. Osgood-Zimmerman
Simon I. Hay
ResearchOpen Access12 Oct 2021
Nature Medicine

Volume: 27, P: 1761-1782
Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

Tweaking immune characteristics of donors and recipients could allow for successful cross-species organ transplantation. Here, the authors show that an anti-CD40 antibody therapy of baboons that received heart transplants from genetically modified pigs is key to their long-term survival.

Muhammad M. Mohiuddin
Avneesh K. Singh
Keith A. Horvath
ResearchOpen Access05 Apr 2016
Nature Communications

Volume: 7, P: 1-10
The immunobiology and clinical use of genetically engineered porcine hearts for cardiac xenotransplantation

Goerlich et al. review the history of cardiac allo- and xenotransplants, the progress in immunomodulation to prevent rejection, the regulatory requirements for clinical application and the lessons learned from the first genetically modified pig-to-human heart xenotransplantation.

Corbin E. Goerlich
Avneesh K. Singh
Muhammad M. Mohiuddin
Reviews09 Aug 2022
Nature Cardiovascular Research

Volume: 1, P: 715-726
Transplantation of a genetically modified porcine heart into a live human

In the second case in which a genetically modified pig heart was transplanted into a living person, the xenografted heart functioned well initially, but antibody-mediated rejection occurred thereafter, pointing to the need for improved strategies to avoid this complication.

Bartley P. Griffith
Alison Grazioli
Muhammad M. Mohiuddin
Research08 Jan 2025
Nature Medicine

Volume: 31, P: 589-598
Pig-to-primate organ transplants require genetic modifications of donor

A raft of alterations to the pig genome — removing three antigen-encoding genes, adding seven human genes and eliminating a retrovirus — allows kidneys to be transplanted into monkeys, with implications for clinical trials.

Muhammad M. Mohiuddin
News & Views11 Oct 2023
Nature

Volume: 622, P: 244-245
A multi-model feature fusion based transfer learning with heuristic search for copy-move video forgery detection

Hessa Alfraihi
Muhammad Swaileh A. Alzaidi
Abdulwhab Alkharashi
ResearchOpen Access08 Feb 2025
Scientific Reports

Volume: 15, P: 1-27
Genetically engineered pig heart transplantation in non-human primates

Singh, Goerlich et al. transplant 10 gene modified pig hearts into non-human primates. Life-supporting function occurred for up to 225 days but there was evidence of adipose deposition, chronic vasculopathy, micro and macro thrombosis, and acute cellular rejection.

Avneesh K. Singh
Corbin E. Goerlich
Muhammad M. Mohiuddin
ResearchOpen Access07 Jan 2025
Communications Medicine

Volume: 5, P: 1-12
At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Munib Mesinovic
Xin Ci Wong
David Zucman
ResearchOpen Access16 Jul 2024
Scientific Reports

Volume: 14, P: 1-43
Heterotopic Porcine Cardiac Xenotransplantation in the Intra-Abdominal Position in a Non-Human Primate Model

Corbin E. Goerlich
Laura DiChiacchio
Muhammad M. Mohiuddin
ResearchOpen Access01 Jul 2020
Scientific Reports

Volume: 10, P: 1-11
ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

Ali Abbas
Sheryl Ann Abdukahil
Luis Felipe Reyes
ResearchOpen Access30 Jul 2022
Scientific Data

Volume: 9, P: 1-22

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Anemia prevalence in women of reproductive age in low- and middle-income countries between 2000 and 2018

Chimeric 2C10R4 anti-CD40 antibody therapy is critical for long-term survival of GTKO.hCD46.hTBM pig-to-primate cardiac xenograft

The immunobiology and clinical use of genetically engineered porcine hearts for cardiac xenotransplantation

Transplantation of a genetically modified porcine heart into a live human

Pig-to-primate organ transplants require genetic modifications of donor

A multi-model feature fusion based transfer learning with heuristic search for copy-move video forgery detection

Genetically engineered pig heart transplantation in non-human primates

At-admission prediction of mortality and pulmonary embolism in an international cohort of hospitalised patients with COVID-19 using statistical and machine learning methods

Heterotopic Porcine Cardiac Xenotransplantation in the Intra-Abdominal Position in a Non-Human Primate Model

ISARIC-COVID-19 dataset: A Prospective, Standardized, Global Dataset of Patients Hospitalized with COVID-19

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