Trypanosoma brucei rhodesienseis one of the causative agents of sleeping sickness, owing to its ability to resist lysis by human serum. In this Opinion article, the authors contend that a pore-forming apolipoprotein known as APOL1 is the factor that is responsible for the trypanolytic activity of human serum.
- Etienne Pays
- Benoit Vanhollebeke
- David Pérez-Morga