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Showing 51–86 of 86 results

Advanced filters: Author: Naoki Toyama Clear advanced filters

Cerebral cortical structural alteration patterns across four major psychiatric disorders in 5549 individuals

Junya Matsumoto
Masaki Fukunaga
Ryota Hashimoto
ResearchOpen Access18 Aug 2023
Molecular Psychiatry

Volume: 28, P: 4915-4923
Clinical utility of circulating tumor DNA sequencing in advanced gastrointestinal cancer: SCRUM-Japan GI-SCREEN and GOZILA studies

An observational study on a large cohort of patients with gastrointestinal cancer demonstrates the utility of ctDNA analysis for accelerating the enrollment of patients in clinical trials with no accompanying deterioration in treatment efficacy.

Yoshiaki Nakamura
Hiroya Taniguchi
Takayuki Yoshino
Research05 Oct 2020
Nature Medicine

Volume: 26, P: 1859-1864
Does surgery improve neurological outcomes in older individuals with cervical spinal cord injury without bone injury? A multicenter study

Satoshi Nori
Kota Watanabe
Satoshi Kato
Research11 Jun 2022
Spinal Cord

Volume: 60, P: 895-902
Differences in clinical characteristics of cervical spine injuries in older adults by external causes: a multicenter study of 1512 cases

Noriaki Yokogawa
Satoshi Kato
Kota Watanabe
ResearchOpen Access23 Sept 2022
Scientific Reports

Volume: 12, P: 1-10
PSA doubling time 4.65 months as an optimal cut-off of Japanese nonmetastatic castration-resistant prostate cancer

Shinichi Sakamoto
Kodai Sato
Hiroshi Kitamura
ResearchOpen Access03 Jul 2024
Scientific Reports

Volume: 14, P: 1-11
Utility of complexity analysis in electroencephalography and electromyography for automated classification of sleep-wake states in mice

Naoki Furutani
Yuki C. Saito
Takeshi Sakurai
ResearchOpen Access24 Jan 2025
Scientific Reports

Volume: 15, P: 1-15
Neural precursor cells are decreased in the hippocampus of the delayed carbon monoxide encephalopathy rat model

Shinichiro Ochi
Keisuke Sekiya
Shu-ichi Ueno
ResearchOpen Access18 Mar 2021
Scientific Reports

Volume: 11, P: 1-10
Association between equivalized annual household income and regular medical visits for hypertensive patients since the COVID-19 outbreak

Maya Toyama
Michihiro Satoh
Takahiro Tabuchi
ResearchOpen Access08 Jan 2025
Hypertension Research

Volume: 48, P: 786-795
Time–outcome relationship in acute large-vessel occlusion exists across all ages: subanalysis of RESCUE-Japan Registry 2

Kenichi Todo
Shinichi Yoshimura
Naoyuki Uchiyama
ResearchOpen Access17 Jun 2021
Scientific Reports

Volume: 11, P: 1-10
Specific effects of antitumor active norspermidine on the structure and function of DNA

Takashi Nishio
Yuko Yoshikawa
Kenichi Yoshikawa
ResearchOpen Access18 Oct 2019
Scientific Reports

Volume: 9, P: 1-12
Predicting coronavirus disease 2019 severity using explainable artificial intelligence techniques

Takuya Ozawa
Shotaro Chubachi
Seiya Imoto
ResearchOpen Access19 Mar 2025
Scientific Reports

Volume: 15, P: 1-12
Shotgun proteomics identification of proteins expressed in the Descemet’s membrane of patients with Fuchs endothelial corneal dystrophy

Tatsuya Nakagawa
Naoki Okumura
Noriko Koizumi
ResearchOpen Access27 Jun 2023
Scientific Reports

Volume: 13, P: 1-13
Rapid isolation of viral integration site reveals frequent integration of HTLV-1 into expressed loci

Tatsuhiko Ozawa
Takahiro Itoyama
Masaharu Isobe
Research01 Mar 2004
Journal of Human Genetics

Volume: 49, P: 154-165
Differences in fractional anisotropy between the patients with schizophrenia and healthy comparison subjects

Daisuke Koshiyama
Masaki Fukunaga
Ryota Hashimoto
Research14 Apr 2020
Molecular Psychiatry

Volume: 25, P: 697-698
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production

Tatsuya Saitoh
Naonobu Fujita
Shizuo Akira
Research05 Oct 2008
Nature

Volume: 456, P: 264-268
The prevalence and clinical features of MYO7A-related hearing loss including DFNA11, DFNB2 and USH1B

Kizuki Watanabe
Shin-ya Nishio
Shunsuke Kondo
ResearchOpen Access09 Apr 2024
Scientific Reports

Volume: 14, P: 1-19
Combined effects of blood pressure and glucose status on the risk of chronic kidney disease

This large-scale longitudinal cohort study showed high BP and diabetes synergistically increased the risk of CKD in individuals without AHT. Strict BP management may play an important role in the early prevention of CKD in individuals with worse glucose status within the young and middle-aged population.

Maya Toyama
Michihiro Satoh
Hirohito Metoki
ResearchOpen Access26 Apr 2024
Hypertension Research

Volume: 47, P: 1831-1841
The real-world selection of first-line systemic therapy regimen for metastatic gastroenteropancreatic neuroendocrine neoplasm in Japan

Shun Yamamoto
Naoki Sakakibara
Akira Kawai
ResearchOpen Access20 Oct 2022
Scientific Reports

Volume: 12, P: 1-8
Magnetoencephalography detects phase-amplitude coupling in Parkinson’s disease

Masataka Tanaka
Takufumi Yanagisawa
Haruhiko Kishima
ResearchOpen Access03 Feb 2022
Scientific Reports

Volume: 12, P: 1-14
Predictors for clinical effectiveness of baricitinib in rheumatoid arthritis patients in routine clinical practice: data from a Japanese multicenter registry

Nobunori Takahashi
Shuji Asai
Toshihisa Kojima
ResearchOpen Access14 Dec 2020
Scientific Reports

Volume: 10, P: 1-10
House mouse Mus musculus dispersal in East Eurasia inferred from 98 newly determined complete mitochondrial genome sequences

Yue Li
Kazumichi Fujiwara
Hitoshi Suzuki
ResearchOpen Access15 Sept 2020
Heredity

Volume: 126, P: 132-147
Streptococcus pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like vesicles via NDP52-delocalization

Ogawa, Takada et al. show that Streptococcus pneumoniae triggers the formation of pneumococcus-containing LC3-associated phagosome-like vacuoles in an early stage of infection. This study suggests a hierarchical autophagy mechanism activated by intracellular bacterial pathogens.

Michinaga Ogawa
Naoki Takada
Makoto Ohnishi
ResearchOpen Access13 Jan 2020
Communications Biology

Volume: 3, P: 1-15
Natural ligand-nonmimetic inhibitors of the lipid-transfer protein CERT

The ceramide transport protein CERT is of potential therapeutic interest but is typically targeted using ceramide-derived ligands. Here the authors use virtual screening and a quantitative surface plasmon resonance assay to identify ceramide-nonmimetic inhibitors of a CERT subdomain and test their activity in live cells.

Naoki Nakao
Masaharu Ueno
Kentaro Hanada
ResearchOpen Access20 Feb 2019
Communications Chemistry

Volume: 2, P: 1-11
Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease

Kyaw Thiha
Yoichi Mashimo
Yoshihiro Onouchi
Research11 Mar 2019
Journal of Human Genetics

Volume: 64, P: 511-519
Functional evaluation of PDGFB-variants in idiopathic basal ganglia calcification, using patient-derived iPS cells

Shin-ichiro Sekine
Masayuki Kaneko
Isao Hozumi
ResearchOpen Access05 Apr 2019
Scientific Reports

Volume: 9, P: 1-11
Clinical Implications of Lysyl Oxidase-Like Protein 2 Expression in Pancreatic Cancer

Nobutake Tanaka
Suguru Yamada
Yasuhiro Kodera
ResearchOpen Access29 Jun 2018
Scientific Reports

Volume: 8, P: 1-9
Therapeutic hypothermia for neonatal encephalopathy: a report from the first 3 years of the Baby Cooling Registry of Japan

Kennosuke Tsuda
Takeo Mukai
Kayo Yoshikawa
ResearchOpen Access04 Jan 2017
Scientific Reports

Volume: 7, P: 1-10
Characteristics of patients with COVID-19 who have deteriorating chest X-ray findings within 48 h: a retrospective cohort study

Tatsuya Kusumoto
Shotaro Chubachi
Koichi Fukunaga
ResearchOpen Access12 Dec 2023
Scientific Reports

Volume: 13, P: 1-10
Febuxostat and renal outcomes: post-hoc analysis of a randomized trial

Kentaro Kohagura
Sunao Kojima
Hisao Ogawa
Research07 Feb 2023
Hypertension Research

Volume: 46, P: 1417-1422
Predictors of early remission of proteinuria in adult patients with minimal change disease: a retrospective cohort study

Ryohei Yamamoto
Enyu Imai
Hiroyuki Komatsu
ResearchOpen Access13 Jun 2022
Scientific Reports

Volume: 12, P: 1-12
Corticosteroids for hospitalized patients with mild to critically-ill COVID-19: a multicenter, retrospective, propensity score-matched study

Satoshi Ikeda
Toshihiro Misumi
Takashi Ogura
ResearchOpen Access21 May 2021
Scientific Reports

Volume: 11, P: 1-13
Eucalyptus oil reduces allergic reactions and suppresses mast cell degranulation by downregulating IgE-FcεRI signalling

Tomoya Nakamura
Naoki Yoshida
Yoshihiko Kojima
ResearchOpen Access01 Dec 2020
Scientific Reports

Volume: 10, P: 1-15
Genome-wide linkage analysis of type 2 diabetes mellitus reconfirms the susceptibility locus on 11p13–p12 in Japanese

Hajime Nawata
Senji Shirasawa
Takehiko Sasazuki
Research01 Nov 2004
Journal of Human Genetics

Volume: 49, P: 629-634
Higher longitudinal brain white matter atrophy rate in aquaporin-4 IgG-positive NMOSD compared with healthy controls

Hiroki Masuda
Masahiro Mori
Satoshi Kuwabara
ResearchOpen Access03 Aug 2023
Scientific Reports

Volume: 13, P: 1-14
Correction to: Investigation of novel variations of ORAI1 gene and their association with Kawasaki disease

Kyaw Thiha
Yoichi Mashimo
Yoshihiro Onouchi
Amendments and Corrections31 Jul 2019
Journal of Human Genetics

Volume: 64, P: 1049
IκBα independent induction of NF-κB and its inhibition by DHMEQ in Hodgkin/Reed-Sternberg cells

Mariko Watanabe
Md Zahidunnabi Dewan
Ryouichi Horie
Research19 Feb 2007
Laboratory Investigation

Volume: 87, P: 372-382

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