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Showing 1–4 of 4 results
Advanced filters: Author: Nawsad Alam Clear advanced filters

  • If erythrocyte invasion is blocked during the blood stage of infection by Plasmodium parasites, malaria can be prevented. In this Review, structural insights on erythrocyte invasion by the merozoite form of Plasmodium are discussed in the context of rational design of a blood-stage malaria vaccine.

    • Nawsad Alam
    • Brendan Farrell
    • Matthew K. Higgins
    Reviews
    Nature Reviews Microbiology
    P: 1-14

  • Structural studies show how the PfRCR complex of Plasmodium falciparum forms a bridge between erythrocyte and parasite membranes, and how PfCyRPA-binding antibodies neutralize invasion through a steric mechanism, opening the way to new approaches in rational vaccine design.

    • Brendan Farrell
    • Nawsad Alam
    • Matthew K. Higgins
    ResearchOpen Access
    Nature
    Volume: 625, P: 578-584

  • This month’s Under the Lens discusses how structural studies of the SARS-CoV-2 spike glycoprotein might guide a path towards a vaccine.

    • Nawsad Alam
    • Matthew K. Higgins
    Comments & Opinion
    Nature Reviews Microbiology
    Volume: 18, P: 414