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Advanced filters: Author: Nicolas Pedroncelli Clear advanced filters

Manufacturing synthetic viscoelastic antigen-presenting cells for immunotherapy

Protocol for fabricating synthetic viscoelastic antigen-presenting cells and their application in T cell engineering. These synthetic cells support robust T cell activation and expansion and improve chimeric antigen receptor transduction efficiency.

Zeyang Liu
Yan-Ruide Li
Song Li
Protocols09 Oct 2025
Nature Protocols

P: 1-35
Author Correction: Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs

Mher Garibyan
Tyler Hoffman
Leonardo Morsut
Amendments and CorrectionsOpen Access01 Aug 2024
Nature Communications

Volume: 15, P: 1
Engineering programmable material-to-cell pathways via synthetic notch receptors to spatially control differentiation in multicellular constructs

Synthetic Notch (synNotch) receptors are genetically encoded, modular synthetic receptors that enable mammalian cells to detect environmental signals and respond by activating user-prescribed transcriptional programs. Here the authors apply synNotch receptors to spatially control differentiation of endothelial and skeletal muscle cells in a multicellular construct on assorted biomaterials.

Mher Garibyan
Tyler Hoffman
Leonardo Morsut
ResearchOpen Access13 Jul 2024
Nature Communications

Volume: 15, P: 1-21

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