Advanced search

Filter By:

Journal Check one or more journals to show results from those journals only.

Choose more journals

Article type Check one or more article types to show results from those article types only.
Subject Check one or more subjects to show results from those subjects only.
Date Choose a date option to show results from those dates only.

Custom date range

Clear all filters
Sort by:
Showing 1–3 of 3 results
Advanced filters: Author: Niels Asger Jakobsen Clear advanced filters

  • The discovery that DNA methylation of different CpG sites can serve as digital barcodes of clonal identity led to the development of EPI-Clone, an algorithm that enables single-cell lineage tracing through cellular differentiation at scale.

    • Michael Scherer
    • Indranil Singh
    • Lars Velten
    ResearchOpen Access
    Nature
    Volume: 643, P: 478-487

  • SCIFER detects clonal selection in whole-genome sequencing data using a population genetics model. Applied to a range of somatic tissues, SCIFER quantifies stem cell dynamics and infers clonal ages and sizes without requiring knowledge of driver events.

    • Verena Körber
    • Niels Asger Jakobsen
    • Thomas Höfer
    ResearchOpen Access
    Nature Genetics
    Volume: 57, P: 1718-1729

  • ADP-heptose binds to ALPK1, triggering transcriptional reprogramming and NF-κB activation, endowing pre-leukaemic cells with a competitive advantage due to excessive clonal proliferation.

    • Puneet Agarwal
    • Avery Sampson
    • Daniel T. Starczynowski
    ResearchOpen Access
    Nature
    Volume: 642, P: 201-211