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Showing 1–50 of 1992 results

Advanced filters: Author: O. O’Brien Clear advanced filters

National survey of the occurrence of antimicrobial agents in Australian wastewater and their socioeconomic correlates

The use of antimicrobial agents can exacerbate the proliferation of antimicrobial resistance genes, which can put public health at risk; evaluating this risk requires proper monitoring. An extensive investigation of Australian wastewater reveals a distinct correlation between the type of antimicrobial used and the socioeconomic status of the population.

Jinglong Li
Jake W. O’Brien
Kevin V. Thomas
Research03 Dec 2024
Nature Water

Volume: 2, P: 1166-1177
Geographic spillover of antimicrobial resistance from mass distribution of azithromycin

After two years of mass azithromycin distribution to preschool age children in rural Niger, in this study, authors present evidence that selection of antibiotic resistance genes was not spread from treated villages to nearby untreated villages.

Ariktha Srivathsan
Ahmed M. Arzika
Benjamin F. Arnold
ResearchOpen Access29 Jan 2026
Nature Communications

P: 1-11
Urinary clusterin as a biomarker of human kidney disease progression and response to the endothelin receptor antagonist atrasentan: An exploratory analysis from the SONAR trial

The SONAR trial showed that the endothelin receptor antagonist atrasentan improves kidney outcomes in patients with type 2 diabetes and chronic kidney disease, though individual responses varied. Here the authors report exploratory analyses of the SONAR trial that identify urinary clusterin as a potential predictor of kidney disease progression and response atrasentan in type 2 diabetes.

Wenjun Ju
Viji Nair
Hiddo J. L. Heerspink
ResearchOpen Access07 Feb 2026
Nature Communications

P: 1-16
Variability in the Aggregation of Human Platelets by adrenaline

J. R. O'BRIEN
Research20 Jun 1964
Nature

Volume: 202, P: 1188-1190
Some Effects of Adrenaline and Anti-Adrenaline Compounds on Platelets in vitro and in vivo

J. R. O'BRIEN
Research23 Nov 1963
Nature

Volume: 200, P: 763-764
Limited herbivore migration during the Last Glacial Period of Kenya

Analysing strontium isotope ratios for individuals of 18 bovid and equid species dating to the Last Glacial Period (115–11.7 ka), the authors find that 16 of these species lack definitive evidence of migration, even those species that are long-distance migrants today.

Kaedan O’Brien
Katya Podkovyroff
J. Tyler Faith
Research27 May 2024
Nature Ecology & Evolution

Volume: 8, P: 1191-1198
Improved polygenic risk prediction models for breast cancer subtypes in women of African ancestry

Application of multiancestry and ensemble-based approaches yields improved polygenic risk prediction models for breast cancer and its subtypes among women of African ancestry.

James L. Li
Haoyu Zhang
Dezheng Huo
Research02 Feb 2026
Nature Genetics

P: 1-10
Contamination of Hodgkin's disease cell cultures

Nancy L. Harris
David L. Gang
Stephen J. O'Brien
Research22 Jan 1981
Nature

Volume: 289, P: 228-230
Laser Interferometry of a Dropping Mercury Electrode

J. LEJA
R. N. O'BRIEN
Research18 Jun 1966
Nature

Volume: 210, P: 1217-1219
Genetic variance of laboratory outbred Swiss mice

M. Catherine Rice
Stephen J. O'Brien
Research10 Jan 1980
Nature

Volume: 283, P: 157-161
Toluene degradation products in simulated atmospheric conditions

Bruce E. Dumdei
Robert J. O'Brien
Research20 Sept 1984
Nature

Volume: 311, P: 248-250
Altered cerebrovascular haemodynamics in Parkinson’s disease: Insights from 4D flow MRI

Ashley R. Deane
Daniel J. Myall
Tracy R. Melzer
ResearchOpen Access13 Feb 2026
npj Parkinson's Disease

P: 1-14
Vitamin B₄ and Adenine

R. D. HEARD
H. W. KINNERSLEY
V. READER
Research29 Apr 1933
Nature

Volume: 131, P: 617-618
Three autosomal dominant corneal dystrophies map to chromosome 5q

Edwin M. Stone
William D. Mathers
Val C. Sheffield
Research01 Jan 1994
Nature Genetics

Volume: 6, P: 47-51
Development of deep learning model to screen for primary open-angle glaucoma in African ancestry individuals

Shuo Li
Rebecca Salowe
Osbert Bastani
ResearchOpen Access06 Feb 2026
npj Digital Medicine

P: 1-8
Synaptic and intrinsic membrane defects disrupt early neural network dynamics in Down syndrome

Down syndrome (DS) increases gene dosage that disrupts neurodevelopment and cognition. Using human-derived isogenic neurons, this study reveals altered network activity, synaptic dysfunction, and ion channel defects underlying DS neural impairment.

Saad B. Hannan
Ivan Alić
Trevor G. Smart
ResearchOpen Access22 Jan 2026
Nature Communications

Volume: 17, P: 1-14
Geomagnetically Trapped Radiation Produced by a High-Altitude Nuclear Explosion on July 9, 1962

B. J. O'BRIEN
C. D. LAUGHLIN
J. A. VAN ALLEN
Research08 Sept 1962
Nature

Volume: 195, P: 939-943
Action of Schradan in the Cockroach

R. D. O'BRIEN
E. Y. SPENCER
Research05 Jan 1957
Nature

Volume: 179, P: 52-53
Mapping of an endogenous retroviral sequence to human chromosome 18

Stephen J. O'Brien
Tom I. Bonner
William G. Nash
Research05 May 1983
Nature

Volume: 303, P: 74-77
Activation of Thionophosphates by Liver Microsomes

R. D. O'BRIEN
Research10 Jan 1959
Nature

Volume: 183, P: 121-122
Changes in Platelet Membranes possibly associated with Platelet Stickiness

J. R. O'BRIEN
Research03 Dec 1966
Nature

Volume: 212, P: 1057-1058
Free Convection in Micro-electrolysis Cells

R. N. O'BRIEN
Research04 Jan 1964
Nature

Volume: 201, P: 74-75
Palaeontological and molecular views of panda phylogeny

STEPHEN J. O'BRIEN
WILLIAM G. NASH
MITCH E. BUSH
Research01 Jan 1986
Nature

Volume: 319, P: 428
Ultrafast acousto-plasmonic control and sensing in complex nanostructures

The nanometre length scale of plasmonic structures leads to vibrational dynamics at high frequencies, which could be exploited for sensitive optical detectors. O'Brien et al. show that they can detect spatial properties of phonon modes in multimodal plasmonic structures, revealing complex nanomechanical dynamics.

Kevin O’Brien
N. D. Lanzillotti-Kimura
Xiang Zhang
Research04 Jun 2014
Nature Communications

Volume: 5, P: 1-6
Are the Lsh and Ity disease resistance genes at one locus on mouse chromosome 1?

Janet E. Plant
Jenefer M. Blackwell
A. A. Glynn
Research10 Jun 1982
Nature

Volume: 297, P: 510-511
Changes in Intracellular Hydrogen Ion Activity in Acute Experimental Salicylate Intoxication

J B Moon
D O'Brien
Research01 Jul 1967
Pediatric Research

Volume: 1, P: 277-286
An Abnormal Human Fœtal Hæmoglobin with an Abnormal Alpha-Polypeptide Chain

HELEN M. RANNEY
CATHLEEN O'BRIEN
ALAN S. JACOBS
Research26 May 1962
Nature

Volume: 194, P: 743-745
Atmospheric radioactivity and variations in the solar neutrino flux

A. de la Zerda Lerner
K. O'Brien
Research26 Nov 1987
Nature

Volume: 330, P: 353-354
Anti-inflammatory therapy with low-dose IL-2 in acute coronary syndromes: a randomized phase 2 trial

In a randomized phase 2 trial in patients with acute coronary syndrome and high levels of the inflammation biomarker C-reactive protein, treatment with low-dose interleukin-2 increased the numbers of regulatory T cells and reduced arterial inflammation, compared to placebo.

Rouchelle S. Sriranjan-Rothwell
Tian X. Zhao
Leanne Masters
ResearchOpen Access08 Jan 2026
Nature Medicine

Volume: 32, P: 624-632
New Light on How Aspirin Works

H. O. J. COLLIER
Research05 Jul 1969
Nature

Volume: 223, P: 35-37
An updated modeling framework and sensitivity analysis of methodology for the climate health vulnerability index

This study develops a climate health vulnerability index for New York State, presenting an updated modeling framework and showing through sensitivity analyses that design choices affect the identification of vulnerable populations.

Pin Wang
Fiona O’Brien
Kai Chen
ResearchOpen Access08 Jan 2026
Nature Communications

Volume: 17, P: 1-11
Validation of chemoresistance phenotypes in pleural mesothelioma across 2D, 3D, and in vivo models

Huaikai Shi
Sakthi Priya Selvamani
Yuen Yee Cheng
ResearchOpen Access11 Feb 2026
Scientific Reports

P: 1-14
Reproductive and genetic consequences of founding isolated lion populations

D. E. Wildt
M. Bush
S. J. O'Brien
Research24 Sept 1987
Nature

Volume: 329, P: 328-331
Effect of Excess Phenylalanine and of Other Amino Acids on Brain Developmen in the Infant Rat

H Peter Chase
Donough O'Brien
Research01 Jan 1970
Pediatric Research

Volume: 4, P: 96-102
A widespread protein misfolding mechanism is differentially rescued in vitro by chaperones based on gene essentiality

Non-covalent lasso entanglements are pervasive structural features of increasing importance. Here, the authors show that these entanglements are associated with in vitro misfolding across the E. coli proteome and that chaperones preferentially rescue such misfolding in essential proteins.

Ian Sitarik
Quyen V. Vu
Edward P. O’Brien
ResearchOpen Access12 Dec 2025
Nature Communications

Volume: 16, P: 1-14
Correlative genetic variation in natural populations of cats, mice and men

Stephen J. O'Brien
Mitchell H. Gail
David L. Levin
Research11 Dec 1980
Nature

Volume: 288, P: 580-583
Abnormal mRNA for argininosuccinate synthetase in citrullinaemia

Tsung-Sheng Su
Arthur L. Beaudet
William E. O'Brien
Research10 Feb 1983
Nature

Volume: 301, P: 533-534
Archæology in South and East Africa

T. F. DREYER
Research01 Nov 1935
Nature

Volume: 136, P: 872
Somatic deficiency of the human E3 ubiquitin ligase CBL in leukocytes impairs B cell but not T cell development and function

Bohlen and colleagues report that the E3 ubiquitin ligase CBL is necessary for the development, tolerance and activation of B cells in humans, unlike in mice where CBL deficiency results in loss of T cells.

Taja Vatovec
Anna-Lena Neehus
Jonathan Bohlen
ResearchOpen Access15 Jan 2026
Nature Immunology

Volume: 27, P: 308-322
Action of D-1-Alkyl-2-(α-Hydroxybenzyl)-Benzimidazoles on Tissue-Culture Cells Infected with Poliovirus

D. G. O'SULLIVAN
DANICA PANTIC
A. K. WALLIS
Research25 Jan 1964
Nature

Volume: 201, P: 378-379
Oligosaccharide ligands for NKR-P1 protein activate NK cells and cytotoxicity

Karel Bezouška
Chun-Ting Yuen
Ten Feizi
Research10 Nov 1994
Nature

Volume: 372, P: 150-157
Phospholipids, Proteins and Platelet-Lipoid

J. R. O'BRIEN
Research08 Feb 1958
Nature

Volume: 181, P: 420
Anchored reference loci for comparative genome mapping in mammals

Stephen J. O'Brien
James E. Womack
Neal G. Copeland
Reviews01 Feb 1993
Nature Genetics

Volume: 3, P: 103-112
The impact of an oral purified microbiome therapeutic on the gastrointestinal microbiome

An exploratory analysis of the phase 3 ECOSPOR III trial shows that a higher dosage of the oral microbiome therapeutic VOWST led to enhanced pharmacokinetics, increased species engraftment and altered microbiome and metabolite profiles, providing mechanistic insights into how it may prevent Clostridioides difficile infection recurrence.

Jessica A. Bryant
Marin Vulić
Matthew R. Henn
ResearchOpen Access05 Jan 2026
Nature Medicine

Volume: 32, P: 186-196
A molecular solution to the riddle of the giant panda's phylogeny

Stephen J. O'Brien
William G. Nash
Raoul E. Benveniste
Research12 Sept 1985
Nature

Volume: 317, P: 140-144
Comparative anchor tagged sequences (CATS) for integrative mapping of mammalian genomes

Leslie A. Lyons
Thomas F. Laughlin
Stephen J. O'Brien
Research01 Jan 1997
Nature Genetics

Volume: 15, P: 47-56
Polymerized Supramolecular Assemblies

David F O’Brien
Thauming Kuo
Henry Lamparski
Research01 May 1991
Polymer Journal

Volume: 23, P: 619-628
Mechanobiologically-optimized non-resorbable artificial bone for patient-matched scaffold-guided bone regeneration

Scaffold-guided bone regeneration is a promising treatment strategy for segmental defects, but clinical translation has been hindered, partially by mechanical function limitations. Here, Clark et al. describes a permanent printed polymer with a resorbable stem cell laden ceramic core for reconstructing segmental mandibular defects, which is tested in an ovine model.

Jonathan R. Clark
D. S. Abdullah Al Maruf
Jeremy M. Crook
ResearchOpen Access24 Oct 2025
Nature Communications

Volume: 16, P: 1-20
Possible Discovery of Ion-Pairs by Interferometry

R. N. O'BRIEN
C. ROSENFIELD
Research10 Sept 1960
Nature

Volume: 187, P: 935-936
Molecular mechanisms of tirapazamine (SR 4233, Win 59075)-induced hepatocyte toxicity under low oxygen concentrations

S Khan
PJ O'Brien
Research01 Apr 1995
British Journal of Cancer

Volume: 71, P: 780-785

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