Nature Search

Thyroid Hormones in Human Milk and their Influence on Thyroid Function of Breast-Fed Babies

Hitoshi Mizuta
Nobuyuki Amino
Kiyoshi Miyai
Research01 Jun 1983
Pediatric Research

Volume: 17, P: 468-471
Isolation and localization of an IDDMK1,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locus

Shiga Hasuike
Kiyonori Miura
Mutuo Ishikawa
Research01 Aug 1999
Journal of Human Genetics

Volume: 44, P: 343-347
N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation

The interferon-inducible RNA-binding protein N4BP1 binds to and degrades HIV-1 mRNAs, thus inhibiting viral degradation and promoting viral latency. However, metacaspase-mediated degradation of N4BP1 following activation of CD4⁺ T cells facilitates HIV-1 latency reversal.

Daichi Yamasoba
Kei Sato
Osamu Takeuchi
Research27 May 2019
Nature Microbiology

Volume: 4, P: 1532-1544
Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

In patients with ulcerative colitis, chronic inflammation can lead to remodelling of the colorectal epithelium through positive selection of clones with mutations in genes related to IL-17 signalling, which, however, might be negatively selected during colitis-associated carcinogenesis.

Nobuyuki Kakiuchi
Kenichi Yoshida
Seishi Ogawa
Research18 Dec 2019
Nature

Volume: 577, P: 260-265
Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta

Kiyonori Miura
Osamu Miyoshi
Tadayuki Ishimaru
Research01 Jan 1999
Journal of Human Genetics

Volume: 44, P: 1-9
A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs

Necroptotic cells activate MLKL and release inflammatory DAMPs, although the underlying regulatory mechanisms of this process are poorly understood. Here, Murai et al. develop a necroptosis-specific FRET sensor (SMART) that monitors MLKL membrane translocation to identify two modes of DAMP release.

Shin Murai
Yoshifumi Yamaguchi
Hiroyasu Nakano
ResearchOpen Access26 Oct 2018
Nature Communications

Volume: 9, P: 1-17
Molecular Characterization of Undifferentiated-Type Gastric Carcinoma

Gen Tamura
Kiyoshi Sato
Teiichi Motoyama
Research01 Apr 2001
Laboratory Investigation

Volume: 81, P: 593-598
Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia

Takashi Tsuchiya
Gen Tamura
Stephen J Meltzer
Research28 Jul 2000
Oncogene

Volume: 19, P: 3642-3646
Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Ai Kurogi
Daisuke Onozuka
Masayuki Yokota
ResearchOpen Access28 Feb 2022
Scientific Reports

Volume: 12, P: 1-17
Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment

Yuu Nishinarita
Jun Miyoshi
Tadakazu Hisamatsu
ResearchOpen Access26 May 2025
Scientific Reports

Volume: 15, P: 1-15
Autonomous trisomic rescue of Down syndrome cells

Continuously cultivated iPSCs with chromosome 21 trisomy spontaneously reverted to normal diploids. This trisomy rescue occurred without genetic manipulation, chemical treatment, or exposure to irradiation. The revertant cells can serve as a reference for drug screening and as raw materials for regenerative medicine and cell-based therapy.

Momoko Inoue
Kazuhiro Kajiwara
Akihiro Umezawa
ResearchOpen Access13 Feb 2019
Laboratory Investigation

Volume: 99, P: 885-897
Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide

Hiroki Omura
Daisuke Oikawa
Osamu Nureki
ResearchOpen Access10 Oct 2016
Scientific Reports

Volume: 6, P: 1-11
β-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion

Noriyasu Usami
Yoshitaka Sekido
Kaoru Shimokata
Research11 Sept 2003
Oncogene

Volume: 22, P: 7922-7930
A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis

Gen Sobue, Masao Nagasaki and colleagues report a genome-wide association study for amyotrophic lateral sclerosis (ALS) in a large, multi-ethnic cohort comprising Japanese, Chinese, and European ancestry populations. They find a significant association to variants within the ACSL5 gene and identify novel associations with 4 additional genes using a gene-based approach.

Ryoichi Nakamura
Kazuharu Misawa
Gen Sobue
ResearchOpen Access23 Sept 2020
Communications Biology

Volume: 3, P: 1-9
Correction: Corrigendum: Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Osamu Hashizume
Sakiko Ohnishi
Jun-Ichi Hayashi
Amendments and CorrectionsOpen Access05 Oct 2015
Scientific Reports

Volume: 5, P: 1
Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Osamu Hashizume
Sakiko Ohnishi
Jun-Ichi Hayashi
ResearchOpen Access22 May 2015
Scientific Reports

Volume: 5, P: 1-11
5-Aminosalicylic acid alters the gut microbiota and altered microbiota transmitted vertically to offspring have protective effects against colitis

Haruka Wada
Jun Miyoshi
Tadakazu Hisamatsu
ResearchOpen Access28 Jul 2023
Scientific Reports

Volume: 13, P: 1-16

Search

Thyroid Hormones in Human Milk and their Influence on Thyroid Function of Breast-Fed Babies

Isolation and localization of an IDDMK1,2-22-related human endogenous retroviral gene, and identification of a CA repeat marker at its locus

N4BP1 restricts HIV-1 and its inactivation by MALT1 promotes viral reactivation

Frequent mutations that converge on the NFKBIZ pathway in ulcerative colitis

Repeat-directed isolation of a novel gene preferentially expressed from the maternal allele in human placenta

A FRET biosensor for necroptosis uncovers two different modes of the release of DAMPs

Molecular Characterization of Undifferentiated-Type Gastric Carcinoma

Distinct methylation patterns of two APC gene promoters in normal and cancerous gastric epithelia

Influence of hospital capabilities and prehospital time on outcomes of thrombectomy for stroke in Japan from 2013 to 2016

Characteristic gene expression profile of intestinal mucosa early in life promotes bacterial colonization leading to healthy development of the intestinal environment

Autonomous trisomic rescue of Down syndrome cells

Structural and Functional Analysis of DDX41: a bispecific immune receptor for DNA and cyclic dinucleotide

β-catenin inhibits cell growth of a malignant mesothelioma cell line, NCI-H28, with a 3p21.3 homozygous deletion

A multi-ethnic meta-analysis identifies novel genes, including ACSL5, associated with amyotrophic lateral sclerosis

Correction: Corrigendum: Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

Epigenetic regulation of the nuclear-coded GCAT and SHMT2 genes confers human age-associated mitochondrial respiration defects

5-Aminosalicylic acid alters the gut microbiota and altered microbiota transmitted vertically to offspring have protective effects against colitis

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