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Reply to — Damon Biotech's Pre-Public Investment—semantics and Econometrics

James Murray
Correspondence01 Sept 1984
Bio/Technology

Volume: 2, P: 733
Natural atmospheric ¹⁴C variation and the Suess effect

P. P. TANS
A. F. M. DE JONG
W. G. MOOK
Research30 Aug 1979
Nature

Volume: 280, P: 826-828
Branched-chain amino acid specialization drove diversification within Calditenuaceae (Caldarchaeia) and enables their cultivation

Many thermophiles that are abundant in geothermal systems have never been cultivated and are poorly understood. Here, Lai et al. describe the cultivation of one such organism, a deeply branching member of the archaeal phylum Thermoproteota, and provide evidence that it has evolved to specialize in branched-chain amino acid metabolism.

Dengxun Lai
Damon Mosier
Brian P. Hedlund
ResearchOpen Access04 Feb 2026
Nature Communications

P: 1-16
Nuclear Fission in the Early History of the Earth

P. K. KURODA
Research02 Jul 1960
Nature

Volume: 187, P: 36-38
BACH2 regulates T cell lineage state to enhance CAR T cell function

One of three back-to-back papers to show that dosage of BACH2 can modulate T cell differentiation and function and how we might apply this to enhance CAR T cell therapies for cancer.

Tien-Ching Chang
Amanda Heard
Nathan Singh
Research16 Jan 2026
Nature Immunology

P: 1-12
Atlas-guided discovery of transcription factors for T cell programming

A comprehensive atlas platform integrating transcriptional and epigenetic data enables more precise engineering of T cell states, accelerating the rational design of more effective cellular immunotherapies.

H. Kay Chung
Cong Liu
Wei Wang
ResearchOpen Access04 Feb 2026
Nature

P: 1-11
Abemaciclib in meningiomas with somatic NF2 or CDK pathway alterations: the phase 2 Alliance A071401 trial

In an arm of an ongoing multicenter phase 2 trial testing different therapies in patients with genetically profiled grade 2 or 3 meningiomas, treatment with an oral CDK4/6 inhibitor met the primary endpoint for progression-free survival at 6 months in patients with CDK or NF2 alterations.

Priscilla K. Brastianos
Katharine Dooley
Evanthia Galanis
ResearchOpen Access16 Jan 2026
Nature Medicine

Volume: 32, P: 717-724
Radiocarbon dating of the Shroud of Turin

P. E. Damon
D. J. Donahue
M. S. Tite
Research16 Feb 1989
Nature

Volume: 337, P: 611-615
Microproteins Simba1 and Simba2 activate Wingless signaling during the reactivation of neural stem cells in Drosophila

Drosophila Microproteins Simba1/2 act in neural stem cells and blood-brain-barrier glia to promote reactivation of neural stem cells via activating WNT/Wingless signaling, while human ortholog ZNF706 is found to have a conserved role in activating WNT pathway.

Jiaen Lin
Qiannan Deng
Hongyan Wang
ResearchOpen Access26 Nov 2025
Nature Communications

Volume: 16, P: 1-17
Tuning CAR-T cells by targeting cancer-associated glycan in pancreatic cancer

Components of the glycocalyx have been shown to impair immune cell functions, including of CAR-T cells. Here the authors show that CAR-T cell mediated cytotoxicity in pancreatic cancer models can be enhanced by incorporating non-signalling binding domains that target the glycocalyx.

Sangwoo Park
Cassidy E. Ho
Marcela V. Maus
ResearchOpen Access10 Dec 2025
Nature Communications

Volume: 16, P: 1-15
Television Microscopy: A Flying-spot Interference Television Microscope

P. O'B. MONTGOMERY
L. L. HUNDLEY
Research16 Dec 1961
Nature

Volume: 192, P: 1059-1060
Dietary restriction reprograms CD8⁺ T cell fate to enhance anti-tumour immunity and immunotherapy responses

Dietary restriction promotes the expansion of effector T cells via ketone bodies, which enhances anti-tumour immunity and synergizes with immunotherapy in mice.

Brandon M. Oswald
Lisa M. DeCamp
Russell G. Jones
ResearchOpen Access09 Dec 2025
Nature Metabolism

Volume: 7, P: 2489-2509
Azaserine, A New Tumour-Inhibitory Substance: Isolation and Characterization of Azaserine

QUENTIN R. BARTZ
CAROLE C. ELDER
ALBERT RYDER
Research09 Jan 1954
Nature

Volume: 173, P: 72-73
Azaserine, A New Tumour-Inhibitory Substance: Antibiotic Studies of Azaserine

JOHN EHRLICH
LUCIA E. ANDERSON
JULIAN E. OYAAS
Research09 Jan 1954
Nature

Volume: 173, P: 72
Azaserine, A New Tumour-Inhibitory Substance: Studies with Crocker Mouse Sarcoma 180

C. CHESTER STOCK
H. CHRISTINE REILLY
C. P. RHODAS
Research09 Jan 1954
Nature

Volume: 173, P: 71-72
Identification of Ethanolamine in Fruit Buds of Australian Apple and Peach Trees

G. P. BRINER
V. O. GRASMANIS
Research25 Apr 1964
Nature

Volume: 202, P: 359-360
Structures Corresponding to Terminal Bars and Terminal Web in Many Types of Cells

C. P. LEBLOND
HOLDE PUCHTLER
Y. CLERMONT
Research04 Jun 1960
Nature

Volume: 186, P: 784-788
Cardiac adaptation to endurance exercise training requires suppression of GDF15 via PGC-1α

Khetarpal et al. show that the metabolic regulator PGC-1α is essential in heart muscle cells for exercise-driven cardiac growth, and that suppression of the stress-induced myokine GDF15 is required to enable cardiomyocyte adaptations to training.

Sumeet A. Khetarpal
Haobo Li
Anthony Rosenzweig
Research24 Sept 2025
Nature Cardiovascular Research

Volume: 4, P: 1277-1294
Enabling whole genome sequencing analysis from FFPE specimens in clinical oncology

Artifact mutations from FFPE are a major barrier blocking WGS adoption in clinical oncology. FFPErase, a machine learning framework, eliminates these with high accuracy in multiinstitutional datasets, delivering clinical-grade variant reports.

Dylan Domenico
Gunes Gundem
Elli Papaemmanuil
ResearchOpen Access27 Nov 2025
Nature Communications

Volume: 16, P: 1-16
Haemoglobin Hammersmith (β 42 (CD1) Phe→Ser)

J. V. DACIE
N. K. SHINTON
H. LEHMANN
Research18 Nov 1967
Nature

Volume: 216, P: 663-665
The Thymus and the Precursors of Antigen Reactive Cells

J. F. A. P. MILLER
G. F. MITCHELL
Research18 Nov 1967
Nature

Volume: 216, P: 659-663
Mammalian Cell Fusion : Induction of Premature Chromosome Condensation in Interphase Nuclei

R. T. JOHNSON
P. N. RAO
Research23 May 1970
Nature

Volume: 226, P: 717-722
Cellular Basis of the Immunological Defects in Thymectomized Mice

J. F. A. P. MILLER
G. F. MITCHELL
N. S. WEISS
Research01 Jun 1967
Nature

Volume: 214, P: 992-997
SMAD4 induces opposite effects on metastatic growth from pancreatic tumors depending on the organ of residence

Using mouse pancreatic cancer models, Tsanov et al. show that reactivation of SMAD4 at metastatic sites promotes tumor growth in the lung through RUNX1 but restrains metastatic growth through KLF4 in the liver, influenced by organ-specific epigenetic states.

Kaloyan M. Tsanov
Francisco M. Barriga
Scott W. Lowe
ResearchOpen Access25 Sept 2025
Nature Cancer

Volume: 6, P: 1839-1856
Tertiary Mammalian Faunas and Sediments in Karamoja and Kavirondo, East Africa

W. W. BISHOP
F. WHYTE
Research29 Dec 1962
Nature

Volume: 196, P: 1283-1287
Developmentally regulated genes drive phylogenomic splits in ovule evolution

Making use of phylogenomic and transcriptome analysis of 20 plant species, including 14 gymnosperms, Sondervan et al. uncover candidate ovule genes and find that orthologs with differential tissue expression patterns across species most influence major evolutionary splits of seed plants.

Veronica M. Sondervan
Gil Eshel
Gloria M. Coruzzi
ResearchOpen Access13 Nov 2025
Nature Communications

Volume: 16, P: 1-15
Influence of Cervical Sympathectomy and Pituitary Stalk Section upon Milk Secretion in Goats

G. B. TVERSKOY
Research04 Jun 1960
Nature

Volume: 186, P: 782-784
Molecular Orientation of Some Keratins

C. EARLAND
P. R. BLAKEY
J. G. P. STELL
Research29 Dec 1962
Nature

Volume: 196, P: 1287-1291
Parity and lactation induce T-cell-mediated breast cancer protection

Parity induces an accumulation of CD8⁺ T cells, including cells with a tissue-resident-memory-like phenotype within human normal breast tissue, offering long-term protection against triple-negative breast cancer.

Balaji Virassamy
Franco Caramia
Sherene Loi
ResearchOpen Access20 Oct 2025
Nature

Volume: 649, P: 449-459
Clonal vaccinia virus grown in cell culture as a new smallpox vaccine

Richard Weltzin
Jian Liu
Thomas P Monath
Research17 Aug 2003
Nature Medicine

Volume: 9, P: 1125-1130
Minimal Model for the Mechanism of Antibody Induction and Paralysis by Antigen

P. A. BRETSCHER
M. COHN
Research02 Nov 1968
Nature

Volume: 220, P: 444-448
Ultrastructure of the Node of Ranvier

D. N. LANDON
P. L. WILLIAMS
Research10 Aug 1963
Nature

Volume: 199, P: 575-577
Radiocarbon variations with the 11-year solar cycle during the last century

A. A. Burchuladze
S. V. Pagava
S. UsaČev
Research01 Sept 1980
Nature

Volume: 287, P: 320-322
Approaching soft X-ray wavelengths in nanomagnet-based microwave technology

Integrating spin waves with microwave circuits is promising for microwave nanoelectronics. Here, Yu et al. demonstrate a reconfigurable microwave-to-magnon transducer by covering yttrium iron garnet with small arrays of tailored magnetic nanodisks, which transmits microwave signals via sub-100-nanometer wavelength spin waves.

Haiming Yu
O. d’ Allivy Kelly
D. Grundler
ResearchOpen Access11 Apr 2016
Nature Communications

Volume: 7, P: 1-7
Microwave excitation of spin wave beams in thin ferromagnetic films

P. Gruszecki
M. Kasprzak
W. Śmigaj
ResearchOpen Access14 Mar 2016
Scientific Reports

Volume: 6, P: 1-8
Dispersion-tunable low-loss implanted spin-wave waveguides for large magnonic networks

Silicon-ion-implanted yttrium iron garnet technology enables low-loss and dispersion-tunable magnonic waveguides with spin-wave decay lengths of >100 µm, which pave the way for large-scale, energy-efficient magnonic integrated circuits.

Jannis Bensmann
Robert Schmidt
Rudolf Bratschitsch
ResearchOpen Access09 Jul 2025
Nature Materials

Volume: 24, P: 1920-1926
Genetic manipulation of the human gut bacterium Eggerthella lenta reveals a widespread family of transcriptional regulators

Eggerthella lenta is a prominent human gut bacterium implicated in several physiological processes, but its study has remained limited. Here, by developing a genetic toolbox for E. lenta, the authors provide insights into how the bacterium regulates drug and dietary compound metabolism.

Xueyang Dong
Ben G. H. Guthrie
Emily P. Balskus
ResearchOpen Access09 Dec 2022
Nature Communications

Volume: 13, P: 1-20
Room-temperature chiral magnetic skyrmions in ultrathin magnetic nanostructures

Stable, single magnetic skyrmions are demonstrated at room temperature in ultrathin cobalt nanostructures.

Olivier Boulle
Jan Vogel
Gilles Gaudin
Research25 Jan 2016
Nature Nanotechnology

Volume: 11, P: 449-454
A human in the loop approach to applying large language models for farm management insight

Spyridon Mourtzinis
Tatiane Severo Silva
Shawn P. Conley
ResearchOpen Access02 Dec 2025
Scientific Reports

Volume: 16, P: 1-8
Correlation of bristlecone pine ring widths with atmospheric ¹⁴C variations: a climate–Sun relation

C. P. Sonett
H. E. Suess
Research12 Jan 1984
Nature

Volume: 307, P: 141-143
Poziotinib for EGFR exon 20-insertion NSCLC: Clinical efficacy of the phase 2 ZENITH trial and differential impact of EGFR exon 20 insertion location on sensitivity

The location of EGFR exon 20 loop insertions (EGFRex20ins) has been shown to alter sensitivity to lung cancer therapy. Here, the authors report the results of the ZENITH20 clinical trial investigating poziotinib (EGFR TKI) in lung cancer patients and, combining with a similar trial, investigate how structural differences due to location of EGGFRex20ins alters sensitivity to EGFR TKI.

Xiuning Le
Jacqulyne P. Robichaux
John V. Heymach
ResearchOpen Access24 Sept 2025
Nature Communications

Volume: 16, P: 1-14
Targeting G1–S-checkpoint-compromised cancers with cyclin A/B RxL inhibitors

Dual cyclin A/B RxL inhibitors selectively kill small cell lung cancer cells and other cancer cells with high E2F activity.

Shilpa Singh
Catherine E. Gleason
Matthew G. Oser
ResearchOpen Access20 Aug 2025
Nature

Volume: 646, P: 734-745
Treatment of acute myeloid leukemia models by targeting a cell surface RNA-binding protein

An RNA-binding protein on leukemia cells provides an effective target in mouse models.

Benson M. George
Maria Eleftheriou
Konstantinos Tzelepis
ResearchOpen Access23 Apr 2025
Nature Biotechnology

P: 1-14
The role of APOBEC3B in lung tumor evolution and targeted cancer therapy resistance

Analyses of in vivo models, cell lines and patient-derived samples show that apolipoprotein B mRNA-editing catalytic subunit 3B (APOBEC3B) not only restrains lung tumor initiation but also that its upregulation is associated with resistance to targeted therapies. This study highlights the complex and context-dependent role of APOBEC3B in lung cancer.

Deborah R. Caswell
Philippe Gui
Charles Swanton
ResearchOpen Access04 Dec 2023
Nature Genetics

Volume: 56, P: 60-73
Genomic and transcriptomic analysis of checkpoint blockade response in advanced non-small cell lung cancer

Genomic and transcriptomic analysis of 393 non-small cell lung cancer patients treated with checkpoint inhibitors identifies molecular features associated with response.

Arvind Ravi
Matthew D. Hellmann
Justin F. Gainor
ResearchOpen Access06 Apr 2023
Nature Genetics

Volume: 55, P: 807-819
Complete nucleotide sequence and identification of membrane components of the histidine transport operon of S. typhimurium

C. F. Higgins
P. D. Haag
G. Ferro-Luzzi Ames
Research19 Aug 1982
Nature

Volume: 298, P: 723-727
Dynamic Electrical Resistivity of Iron: Evidence for a New High Pressure Phase

J. Y. WONG
R. K. LINDE
P. S. DE CARLI
Research17 Aug 1968
Nature

Volume: 219, P: 713-714
Energy Spectrum of Primary Cosmic Rays in the Range 10¹⁰–10¹⁵ eV

G. BROOKE
P. J. HAYMAN
A. W. WOLFENDALE
Research29 Jun 1963
Nature

Volume: 198, P: 1293-1294
Chromosome Changes in Human Cells induced by Herpes Simplex, Types 1 and 2

FRANK J. O'NEILL
CHARLES P. MILES
Research23 Aug 1969
Nature

Volume: 223, P: 851-852
Genomic, transcriptomic, and immunogenomic landscape of over 1300 sarcomas of diverse histology subtypes

Sarcoma is a highly heterogeneous disease, which can be caused by a large variety of mutations. Here, the authors utilise multi-omics to characterise a cohort of 1,340 sarcoma tissue specimens to identify key somatic mutations and identify immune subtypes.

Alex Soupir
Oscar E. Ospina
Andrew S. Brohl
ResearchOpen Access06 May 2025
Nature Communications

Volume: 16, P: 1-11

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