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Showing 1–5 of 5 results

Advanced filters: Author: Paul Balbo Clear advanced filters

A neuron type-specific microexon in Ank3/ankyrin-G modulates calcium activity and neuronal excitability

Here researchers reveal a microexon in the Ank3 gene encoding Ankyrin G allows cortical interneurons to fine-tune calcium signaling and firing, revealing the contribution of alternative splicing to the functional diversity among different types of neurons.

Shah Alam
Georgia Dermentzaki
Chaolin Zhang
ResearchOpen Access13 Feb 2026
Nature Communications

P: 1-19
Inhibiting peptidylarginine deiminases (PAD1-4) by targeting a Ca²⁺ dependent allosteric binding site

Protein citrullination regulates the physiological function of proteins and is linked to various autoimmune disorders. Here, the authors report on the allosteric targeting of PAD1-4 leading to broad inhibition of protein citrullination in neutrophils.

Leslie A. Dakin
Li Xing
Mark E. Schnute
ResearchOpen Access16 May 2025
Nature Communications

Volume: 16, P: 1-12
A PLAG1 mutation contributed to stature recovery in modern cattle

Yuri Tani Utsunomiya
Marco Milanesi
José Fernando Garcia
ResearchOpen Access07 Dec 2017
Scientific Reports

Volume: 7, P: 1-15
Binding site elucidation and structure guided design of macrocyclic IL-17A antagonists

Shenping Liu
Leslie A. Dakin
Atli Thorarensen
ResearchOpen Access16 Aug 2016
Scientific Reports

Volume: 6, P: 1-12
The effect of leave policies on increasing fertility: a systematic review

Jac Thomas
Francisco Rowe
Eric S. Lin
ReviewsOpen Access08 Aug 2022
Humanities and Social Sciences Communications

Volume: 9, P: 1-16