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Showing 1–20 of 20 results
Advanced filters: Author: Paul M. Chaikin Clear advanced filters

  • Natural complex systems are often constructed by sequential assembly but this is not readily available for synthetic systems. Here, the authors program the sequential self-assembly of DNA functionalized emulsions by altering the DNA grafted strands.

    • Yin Zhang
    • Angus McMullen
    • Paul M. Chaikin
    ResearchOpen Access
    Nature Communications
    Volume: 8, P: 1-7

  • In an iterative phase 2 trial, patients with metastatic, treatment-refractory, mismatch repair proficient gastrointestinal cancers had responses to neoantigen-reactive tumor-infiltrating lymphocytes but not bulk tumor-infiltrating lymphocytes, highlighting the potential for a refined immune cell therapy approach in this patient population.

    • Frank J. Lowery
    • Stephanie L. Goff
    • Steven A. Rosenberg
    Research
    Nature Medicine
    Volume: 31, P: 1994-2003

  • Understanding the consequences of the interplay of defects and local curvature in crystals is far from complete despite the considerable influence that a defect has on the crystal’s local properties. It is now found that interstitials inserted in curved crystals at oil/glycerol interfaces can fractionate into two dislocations, which glide through the lattice in opposite directions until they get absorbed into existing dislocations, scars or pleats.

    • William T. M. Irvine
    • Mark J. Bowick
    • Paul M. Chaikin
    Research
    Nature Materials
    Volume: 11, P: 948-951

  • Collections of rolling colloids are shown to pinch off into motile clusters resembling droplets sliding down a windshield. These stable dynamic structures are formed through a fingering instability that relies on hydrodynamic interactions alone.

    • Michelle Driscoll
    • Blaise Delmotte
    • Paul Chaikin
    Research
    Nature Physics
    Volume: 13, P: 375-379

  • Hexagons can easily tile a flat surface, but not a curved one. Defects with topological charge (such as heptagons and pentagons) make it easier to tile curved surfaces, such as soccer balls. Here, a new type of defect is reported that accommodates curvature in the same way as fabric pleats. The appearance of such defects on the negatively curved surfaces of stretched colloidal crystals are observed. The results will facilitate the exploration of general theories of defects in curved spaces, the engineering of curved structures and novel methods for soft lithography and directed self-assembly.

    • William T. M. Irvine
    • Vincenzo Vitelli
    • Paul M. Chaikin
    Research
    Nature
    Volume: 468, P: 947-951

  • Functionalizing colloidal particles with DNA is a powerful tool for guiding their assembly, using the complementary ‘sticky ends’ of the molecules. However, other attributes of DNA can be used to engineer interactions between particles more subtly. Temperature- or time-controlled formation of loops or hairpins in DNA provides switchable connections for novel materials from particle assemblies.

    • Mirjam E. Leunissen
    • Rémi Dreyfus
    • Paul M. Chaikin
    Research
    Nature Materials
    Volume: 8, P: 590-595

  • Freezing on a spherical surface is shown to proceed by the sequestration of defects into 12 icosahedrally coordinated ‘seas’ that enable the formation of a crystalline ‘continent’ with long-range orientational order.

    • Rodrigo E. Guerra
    • Colm P. Kelleher
    • Paul M. Chaikin
    Research
    Nature
    Volume: 554, P: 346-350

  • Hydrodynamically coupled rotors can be used to describe interactions ranging from molecular machines to atmospheric dynamics. Modin et al. show that optically-driven rotors in a non-tweezing beam can freely diffuse while spinning asynchronously and develop an analytical hydrodynamic model to explain.

    • Alvin Modin
    • Matan Yah Ben Zion
    • Paul M. Chaikin
    ResearchOpen Access
    Nature Communications
    Volume: 14, P: 1-9

  • The authors introduce a light powered artificial micro-swimmers performing biological-like dynamics relevant for swarm robotics. The experimental dense swarms are shown to form artificial active clusters with internal fluid-like and turbulent dynamics, similar to real swarming bacteria.

    • Matan Yah Ben Zion
    • Yaelin Caba
    • Paul M. Chaikin
    ResearchOpen Access
    Nature Communications
    Volume: 13, P: 1-8

  • A highly selective and efficient approach to covalently bond complementary DNA strands in solution and on surfaces on demand is shown. The approach involves the substitution of a pair of complementary bases by cinnamate-based crosslinks, which can be activated on exposure to ultraviolet light, and allows chemical patterning of flat and curved surfaces down to micrometre and potentially submicrometre resolutions.

    • Lang Feng
    • Joy Romulus
    • Paul Chaikin
    Research
    Nature Materials
    Volume: 12, P: 747-753

  • The volatile-ice-filled basin informally named Sputnik Planum is central to Pluto’s geological activity; this ice layer is organized into cells or polygons, and it is now shown that convective overturn in a several-kilometre-thick layer of solid nitrogen can explain both the presence of the cells and their great width.

    • William B. McKinnon
    • Francis Nimmo
    • K. E. Smith
    Research
    Nature
    Volume: 534, P: 82-85

  • A network of parallel ridges on the northwestern border of Sputnik Planitia on Pluto are the traces of debris material deposited by a glaciation of icy nitrogen that happened early in Pluto’s history, and left there once the N2 ice disappeared by sublimation.

    • Oliver L. White
    • Jeffrey M. Moore
    • Kimberly Ennico
    Research
    Nature Astronomy
    Volume: 3, P: 62-68