Nature Search

A functional role of meningeal lymphatics in sex difference of stress susceptibility in mice

The mechanisms underlying sex differences in response to stress are unclear. Here, the authors show that meningeal lymphatics dysfunction modulates the sex difference in the stress susceptibility to depression- and anxiety-like behaviours in mice.

Weiping Dai
Mengqian Yang
Xiaojing Ye
ResearchOpen Access16 Aug 2022
Nature Communications

Volume: 13, P: 1-21
Pathogenesis of Placental Site Trophoblastic Tumor May Require the Presence of a Paternally Derived X Chromosome

Pei Hui
Vinita Parkash
Maria-Luisa Carcangiu
Research01 Jun 2000
Laboratory Investigation

Volume: 80, P: 965-972
Sustained elevation of MG53 in the bloodstream increases tissue regenerative capacity without compromising metabolic function

MG53 is a protein that regulates the cell membrane repair process, and it’s been suggested that it might play a role in diabetes. Here, the authors demonstrate that circulating MG53 functions as a myokine to facilitate tissue injury-repair and regeneration without impacting glucose handling.

Zehua Bian
Qiang Wang
Jianjie Ma
ResearchOpen Access11 Oct 2019
Nature Communications

Volume: 10, P: 1-16
MG53 suppresses interferon-β and inflammation via regulation of ryanodine receptor-mediated intracellular calcium signaling

TRIM proteins are known to play critical roles in the context of viral infection. Here the authors establish MG53 (TRIM72) suppresses IFN and inflammation by modulation of ryanodine receptor related intracellular calcium induction.

Matthew Sermersheim
Adam D. Kenney
Jianjie Ma
ResearchOpen Access17 Jul 2020
Nature Communications

Volume: 11, P: 1-12
Overexpression of Bax sensitizes prostate cancer cells to TGF-β induced apoptosis

Pei Hui LIN
Zui PAN
Jian Jie MA
Research01 Mar 2005
Cell Research

Volume: 15, P: 160-166
TRIC channels are essential for Ca²⁺ handling in intracellular stores

Cell signalling requires efficient Ca²⁺ mobilization from intracellular stores through Ca²⁺ release channels, and it has been hypothesized that counter movement of ions across the sarcoplasmic reticulum neutralizes the transient negative potential generated by Ca²⁺ release. This paper identifies two trimeric intracellular cation channel subtypes that that could serve a critical role in such charge compensation.

Masayuki Yazawa
Christopher Ferrante
Hiroshi Takeshima
Research05 Jul 2007
Nature

Volume: 448, P: 78-82
An Injectable Oxygen Release System to Augment Cell Survival and Promote Cardiac Repair Following Myocardial Infarction

Zhaobo Fan
Zhaobin Xu
Jianjun Guan
ResearchOpen Access22 Jan 2018
Scientific Reports

Volume: 8, P: 1-22
MG53 protects against contrast-induced acute kidney injury by reducing cell membrane damage and apoptosis

Chao Liu
Yun-hui Hu
Chun-yu Zeng
Research18 May 2020
Acta Pharmacologica Sinica

Volume: 41, P: 1457-1464

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