The role of prolactin in processes such as lactation and reproduction is well established. However, in the past few years, numerous novel functions for this hormone have been elucidated. In this Review, Bernard and colleagues discuss these newly described functions for prolactin, in particular, the mechanisms underlying infertility associated with hyperprolactinaemia, and the discovery of a mutation in the gene that encodes the prolactin receptor.
- Valérie Bernard
- Jacques Young
- Nadine Binart