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Showing 351–400 of 1686 results

Advanced filters: Author: R J Perry Clear advanced filters

Physical and neurobehavioral determinants of reproductive onset and success

John Perry, Ken Ong and colleagues perform a genome-wide association study for reproductive ability, behavior and success to determine underlying genetic factors. They find 38 variants associated with age of first sexual intercourse and show that both physical and neurobehavioral traits influence the onset of reproductive activity.

Felix R Day
Hannes Helgason
John R B Perry
Research18 Apr 2016
Nature Genetics

Volume: 48, P: 617-623
New insights into the genetic etiology of Alzheimer’s disease and related dementias

Meta-analysis of genome-wide association studies on Alzheimer’s disease and related dementias identifies new loci and enables generation of a new genetic risk score associated with the risk of future Alzheimer’s disease and dementia.

Céline Bellenguez
Fahri Küçükali
Jean-Charles Lambert
ResearchOpen Access04 Apr 2022
Nature Genetics

Volume: 54, P: 412-436
Genomic analysis of male puberty timing highlights shared genetic basis with hair colour and lifespan

Age at voice-breaking is used to determine puberty timing in men, recall of which is considered less accurate than age at first menarche in women. Here, the authors perform multi-trait GWAS for male puberty timing by including both age at voice breaking and age of first facial hair for improved phenotype definition and power.

Ben Hollis
Felix R. Day
John R. B. Perry
ResearchOpen Access24 Mar 2020
Nature Communications

Volume: 11, P: 1-10
Penetrance of pathogenic genetic variants associated with premature ovarian insufficiency

Using exome sequencing data from 104,733 postmenopausal women in the UK Biobank, an analysis of 105 gene variants previously reported as associated with premature ovarian insufficiency reveals that most cases are not monogenic.

Saleh Shekari
Stasa Stankovic
Anna Murray
Research22 Jun 2023
Nature Medicine

Volume: 29, P: 1692-1699
Rare coding variants and X-linked loci associated with age at menarche

Previous studies have linked over 100 genomic loci to age-at-menarche but that work was restricted to common autosomal variation. Here, Lunetta et al. identify associations with rare protein-coding and X-linked variants, implicating new mechanisms that regulate puberty timing.

Kathryn L. Lunetta
Felix R. Day
John R. B. Perry
ResearchOpen Access04 Aug 2015
Nature Communications

Volume: 6, P: 1-8
Induction of abnormal development and differentiation in cultured mammary glands by cyclic adenine nucleotide and prostaglandins

Frederick V. Schaefer
R. Philip Custer
Sam Sorof
Research01 Aug 1980
Nature

Volume: 286, P: 807-810
Use of Pigs in Biomedical Research

L. K. BUSTAD
R. O. McCLELLAN
Research06 Nov 1965
Nature

Volume: 208, P: 531-535
Suppressive vaccination with DNA encoding a variable region gene of the T–cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity

Ari Waisman
Pedro J. Ruiz
Lawrence Steinman
Research01 Aug 1996
Nature Medicine

Volume: 2, P: 899-905
Vertical distribution of dimethylsulphide in the marine atmosphere

R. J. Ferek
R. B. Chatfield
M. O. Andreae
Research10 Apr 1986
Nature

Volume: 320, P: 514-516
Did the Dalradian slides originate as extensional faults?

N. J. Soper
R. Anderton
Research26 Jan 1984
Nature

Volume: 307, P: 357-360
Antigen–specific human monoclonal antibodies from mice engineered with human Ig heavy and light chain YACs

L.L. Green
M.C. Hardy
A. Jakobovits
Research01 May 1994
Nature Genetics

Volume: 7, P: 13-21
Binding of an SV40 T antigen-related protein to the DNA of SV40 regulatory mutants

R. McKay
D. DiMaio
Research26 Feb 1981
Nature

Volume: 289, P: 810-813
Haemopoietic colony stimulating factors promote cell survival by suppressing apoptosis

Gwyn T. Williams
Christopher A. Smith
Dale R. Taylor
Research04 Jan 1990
Nature

Volume: 343, P: 76-79
Observation of Desert Locust Swarms by Radar

R. C. RAINEY
Research08 Jan 1955
Nature

Volume: 175, P: 77
‘Endogenous Factor’ in Sporogenesis in Bacteria

V. R. SRINIVASAN
H. ORIN HALVORSON
Research05 Jan 1963
Nature

Volume: 197, P: 100-101
Occurrence of Configurational Inversion during Tritiation by the Wilzbach Method

S. J. ANGYAL
J. L. GARNETT
R. M. HOSKINSON
Research02 Feb 1963
Nature

Volume: 197, P: 485-486
Avoidance of ‘Secondary Disease’ in Radiation Chimæras

D. W. H. BARNES
P. L. T. ILBERY
J. F. LOUTIT
Research15 Feb 1958
Nature

Volume: 181, P: 488
Biogenic Amines and Active Polypeptides in the Skin of Australian Amphibians

V. ERSPAMER
M. ROSEGHINI
A. ANASTASI
Research08 Oct 1966
Nature

Volume: 212, P: 204
The quasi-crystalline phase in the Mg—Al—Zn system

T. Rajasekharan
D. Akhtar
K. Muraleedharan
Research07 Aug 1986
Nature

Volume: 322, P: 528-530
Effect of a Sewage Effluent Discharge on the Deposition of Calcium Carbonate on Shells of the Snail Potamopyrgus jenkinsi (Smith)

R. W. EDWARDS
J. HEYWOOD
Research07 May 1960
Nature

Volume: 186, P: 492-493
Blank et al. reply

L. W. BLANK
R. A. SKEFFINGTON
T. M. ROBERTS
Research25 May 1989
Nature

Volume: 339, P: 265-266
Maturation of p-Aminohippuric Acid Transport in the Developing Rabbit Kidney: Interrelationships of the Individual Components

Barbara R Cole
J Trevor Brocklebank
Alan M Robson
Research01 Oct 1978
Pediatric Research

Volume: 12, P: 992-997
Automated real-world data integration improves cancer outcome prediction

A study generates a clinicogenomics dataset resource, MSK-CHORD, that combines natural language processing-derived clinical annotations with patient medical data from various sources to improve models of cancer outcome.

Justin Jee
Christopher Fong
Xinran Bi
ResearchOpen Access06 Nov 2024
Nature

Volume: 636, P: 728-736
Two point mutations in protocadherin-1 disrupt hantavirus recognition and afford protection against lethal infection

Protocadherin-1 (PCDH1) is a critical host factor for hantaviruses that can cause severe cardiopulmonary syndrome. Here, the authors map the binding site of the viral glycoprotein complex within PCDH1 and show that mutations engineered at this site can protect Syrian hamsters from viral challenge.

Megan M. Slough
Rong Li
Kartik Chandran
ResearchOpen Access24 Jul 2023
Nature Communications

Volume: 14, P: 1-17
Colour contrast sensitivity changes caused by peripheral retinal laser photocoagulation

Chris R Canning
Nick Strong
Geoffrey B Arden
Research01 May 1991
Eye

Volume: 5, P: 348-351
Clinicogenomic landscape of pancreatic adenocarcinoma identifies KRAS mutant dosage as prognostic of overall survival

Analyses of clinical and genomic data from a cohort of 2,336 patients with pancreatic adenocarcinoma find that KRAS dosage gains are a hallmark of disease progression and are predictive of poor outcomes across different disease stages.

Anna M. Varghese
Maria A. Perry
Eileen M. O’Reilly
ResearchOpen Access03 Jan 2025
Nature Medicine

Volume: 31, P: 466-477
Genes for immunoglobulin heavy chain and serum prealbumin protein are linked in mouse

B. A. TAYLOR
D. W. BAILEY
M. WEIGERT
Research21 Aug 1975
Nature

Volume: 256, P: 644-646
Damaging mutations in liver X receptor-α are hepatotoxic and implicate cholesterol sensing in liver health

LXRα is highly expressed in hepatocytes, where it regulates cholesterol abundance and stimulates lipogenesis. The authors provide evidence in humans and mice that impaired LXRα signalling is hepatotoxic, despite its potent lipogenic actions.

Sam M. Lockhart
Milan Muso
Stephen O’Rahilly
ResearchOpen Access25 Sept 2024
Nature Metabolism

Volume: 6, P: 1922-1938
Phosphorylation-regulated CI⁻ channel in CHO cells stably expressing the cystic fibrosis gene

Joseph A. Tabcharani
Xiu-Bao Chang
John W. Hanrahan
Research15 Aug 1991
Nature

Volume: 352, P: 628-631
Polymer crystallization by chemical nucleation

R. Legras
J. P. Mercier
E. Nield
Research04 Aug 1983
Nature

Volume: 304, P: 432-434
Tectonic emplacement of ophiolitic rocks in the Precambrian Mona Complex of Anglesey

R. S. THORPE
Research02 Nov 1978
Nature

Volume: 276, P: 57-58
A Mammalian Activity Rhythm independent of Temperature

G. EDGAR FOLK JUN.
MONA R. MELTZER
RICHARD E. GRINDELAND
Research07 Jun 1958
Nature

Volume: 181, P: 1598
Use of the Kinematograph for Scientific Purposes

R. F. M.
Research04 Feb 1904
Nature

Volume: 69, P: 318
Nomenclature of Living Parasite Material

W. H. R. LUMSDEN
GILLIAN J. C. HARDY
Research01 Mar 1965
Nature

Volume: 205, P: 1032
Diagnostic Significance of Heterogeneous Lactic Dehydrogenases in Malignant Effusions

R. RICHTERICH
K. ZUPPINGER
E. ROSSI
Research01 Jul 1961
Nature

Volume: 191, P: 507-508
A Well-preserved Grizzly Bear Skull recovered from a Late Glacial Deposit near Lake Simcoe, Ontario

R. L. PETERSON
Research18 Dec 1965
Nature

Volume: 208, P: 1233-1234
Use of Adsorption Columns in the Analysis of Emulsions stabilized with Non-ionic Detergents

T. GREEN
R. P. HARKER
F. O. HOWITT
Research02 Oct 1954
Nature

Volume: 174, P: 659
Mapping class I gene sequences in the major histocompatibility complex

Larry R. Pease
Stanley G. Nathenson
Leslie A. Leinwand
Research22 Jul 1982
Nature

Volume: 298, P: 382-385
Cadmium and cobalt substitution for zinc in a marine diatom

N. M. Price
F. M. M. Morel
Research12 Apr 1990
Nature

Volume: 344, P: 658-660
CO₂, CH₄ and N₂O flux through a Wyoming snowpack and implications for global budgets

R. A. Sommerfeld
A. R. Mosier
R. C. Musselman
Research14 Jan 1993
Nature

Volume: 361, P: 140-142
Kinetics, stoichiometry and role of the Na–Ca exchange mechanism in isolated cardiac myocytes

Lynn M. Crespo
Christopher J. Grantham
Mark B. Cannell
Research14 Jun 1990
Nature

Volume: 345, P: 618-621
Possible role of massive black holes in the generation of galactic magnetic fields

Sandip K. Chakrabarti
R. Rosner
S. I. Vainshtein
Research31 Mar 1994
Nature

Volume: 368, P: 434-436
PD-L1–PD-1 interactions limit effector regulatory T cell populations at homeostasis and during infection

Perry et al. demonstrate that regulatory T (T_reg) cell function is restrained by the cell-autonomous action of the checkpoint inhibitor molecule PD-1. This PD-1-dependent mechanism tunes T_reg cell function during homeostasis and infection.

Joseph A. Perry
Lindsey Shallberg
Christopher A. Hunter
Research18 Apr 2022
Nature Immunology

Volume: 23, P: 743-756
Ribosomal RNA sequence suggests microsporidia are extremely ancient eukaryotes

C. R. Vossbrinck
J. V. Maddox
C. R. Woese
Research26 Mar 1987
Nature

Volume: 326, P: 411-414
Chemical structure of the morphogen differentiation inducing factor from Dictyostelium discoideum

Howard R. Morris
Graham W. Taylor
Robert R. Kay
Research27 Aug 1987
Nature

Volume: 328, P: 811-814
Pregnancy in the hyrax and erythrocyte metabolism of progesterone

R. B. HEAP
S. GOMBE
J. B. SALE
Research30 Oct 1975
Nature

Volume: 257, P: 809-811
Translocation of c-abl oncogene correlates with the presence of a Philadelphia chromosome in chronic myelocytic leukaemia

Claus R. Bartram
Annelies de Klein
John Groffen
Research17 Nov 1983
Nature

Volume: 306, P: 277-280
Restoration of Norwegian lakes by reduction in sulphur deposition

R. F. Wright
A. Henriksen
Research29 Sept 1983
Nature

Volume: 305, P: 422-424
Regulation of a wheat promoter by abscisic acid in rice protoplasts

William R. Marcotte Jr
Christopher C. Bayley
Ralph S. Quatrano
Research29 Sept 1988
Nature

Volume: 335, P: 454-457
Primary structure of dystrophin-related protein

J. M. Tinsley
D. J. Blake
K. E. Davies
Research10 Dec 1992
Nature

Volume: 360, P: 591-593

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