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Showing 1–50 of 170 results

Advanced filters: Author: R Lama Clear advanced filters

Arginine-Vasopressin (AVP) Plays a Role in the Maintenance of the Vascular Tone in Normoxia in the Llama Fetus (Lama glama)

R Riquelme
E Sanhueza
A Llanos
Research01 Nov 1998
Pediatric Research

Volume: 44, P: 816
Seasonal changes in energy expenditure, body temperature and activity patterns in llamas (Lama glama)

Alexander Riek
Lea Brinkmann
Martina Gerken
ResearchOpen Access08 Aug 2017
Scientific Reports

Volume: 7, P: 1-12
Naturally occurring antibodies devoid of light chains

C. Hamers-Casterman
T. Atarhouch
R. Hammers
Research03 Jun 1993
Nature

Volume: 363, P: 446-448
Liquid application method for time-resolved analyses by serial synchrotron crystallography

A rapid sample mixing approach enables time-resolved structural studies of enzymatic reactions using serial synchrotron crystallography.

Pedram Mehrabi
Eike C. Schulz
R. J. Dwayne Miller
Research16 Sept 2019
Nature Methods

Volume: 16, P: 979-982
Differential regulation of the apoptotic machinery during megakaryocyte differentiation and platelet production by inhibitor of apoptosis protein Livin

I Abd-Elrahman
V Deutsch
D Ben-Yehuda
ResearchOpen Access28 Nov 2013
Cell Death & Disease

Volume: 4, P: e937
Biologically inspired neuromorphic-XAI synergy for transparent and low-carbon healthcare intelligence

Akey Sungheetha
Rajesh Sharma R.
Sumendra Yogarayan
ResearchOpen Access20 Feb 2026
Scientific Reports

P: 1-36
Breath-based stratification of asthma severity using the MISTRAL platform with integrated H₂S sensor and clinical validation

R. Germinario
E. Andriani
G. Scioscia
ResearchOpen Access24 Dec 2025
Scientific Reports

Volume: 16, P: 1-10
Rab35 governs apicobasal polarity through regulation of actin dynamics during sprouting angiogenesis

The promiscuous GTPase Rab35 has been shown to be involved in many important cellular functions. In this article, Francis et al. illustrate how Rab35 acts as a critical brake to actin remodeling during sprouting angiogenesis and how it is necessary for proper blood vessel development.

Caitlin R. Francis
Hayle Kincross
Erich J. Kushner
ResearchOpen Access08 Sept 2022
Nature Communications

Volume: 13, P: 1-17
Use of concomitant inhaled corticosteroids: pooled data from two phase III studies of aclidinium plus formoterol in COPD

Anthony D’Urzo
Dave Singh
Esther Garcia Gil
ResearchOpen Access24 Feb 2017
npj Primary Care Respiratory Medicine

Volume: 27, P: 1-5
A service evaluation following the implementation of computer guided consultation software to support primary care reviews for chronic obstructive pulmonary disease

B. Chakrabarti
E. McKnight
R. M. Angus
ResearchOpen Access11 Mar 2025
npj Primary Care Respiratory Medicine

Volume: 35, P: 1-9
Localized transmission of an aquatic pathogen drives hidden epidemics and population collapse in a terrestrial host

Fine-scale field analysis and modelling of the spatial dynamics of infection of Darwin’s frogs with Batrachochytrium dendrobatidis fungus identifies highly localized transmission dynamics that generate clustered epidemics and can drive collapse of local subpopulations.

Andrés Valenzuela-Sánchez
Soledad Delgado-Oyarzún
Leonardo D. Bacigalupe
ResearchOpen Access02 Jan 2026
Nature Ecology & Evolution

Volume: 10, P: 308-317
Impact of umeclidinium/vilanterol dual bronchodilator therapy on pulmonary function and inflammatory responses in stable COPD patients

Rongbin Jiang
Weijie Zhan
Jiachun Li
ResearchOpen Access13 Nov 2025
Scientific Reports

Volume: 15, P: 1-16
Impact of simple interventions on neonatal mortality in a low-resource teaching hospital in India

R Agarwal
K Agarwal
S Seetaraman
Research14 Dec 2006
Journal of Perinatology

Volume: 27, P: 44-49
Larix species range dynamics in Siberia since the Last Glacial captured from sedimentary ancient DNA

Using ancient sedimentary DNA from up to 50 kya, dramatic distributional shifts are documented in two dominant boreal larch species, likely guided by environmental changes suggesting climate as a strong determinant of species distribution.

Luise Schulte
Stefano Meucci
Ulrike Herzschuh
ResearchOpen Access09 Jun 2022
Communications Biology

Volume: 5, P: 1-11
Quantum jumps of conductance during formation of membrane channels at cell–cell junction

W. R. Loewenstein
Y. Kanno
S. J. Socolar
Research13 Jul 1978
Nature

Volume: 274, P: 133-136
Author Correction: Forced oscillation technique in progressive pulmonary fibrosis in a single-center retrospective study

A. Denis
M. Henket
J. Guiot
Amendments and CorrectionsOpen Access29 Jan 2026
Scientific Reports

Volume: 16, P: 1-4
Forced oscillation technique in progressive pulmonary fibrosis in a single-center retrospective study

A. Denis
M. Henket
J. Guiot
ResearchOpen Access02 May 2025
Scientific Reports

Volume: 15, P: 1-10
Burden of illness among patients with asthma prescribed inhaled corticosteroids/long-acting β₂-agonists

Shiyuan Zhang
Alexandrosz Czira
Mark Small
ResearchOpen Access26 Feb 2025
npj Primary Care Respiratory Medicine

Volume: 35, P: 1-10
Chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is characterized by damage to the lungs and consequent obstruction of the airways, and is strongly associated with smoking. This Primer discusses the causes and mechanisms of COPD and approaches to its diagnosis and management.

Peter J. Barnes
Peter G. J. Burney
Emiel F. M. Wouters
Reviews03 Dec 2015
Nature Reviews Disease Primers

Volume: 1, P: 1-21
Neotropical Africanized honey bees have African mitochondrial DNA

Deborah Roan Smith
Orley R Taylor
Wesley M. Brown
Research18 May 1989
Nature

Volume: 339, P: 213-215
A New Natural History ¹

R. L.
News16 Apr 1903
Nature

Volume: 67, P: 562-563
Structural signatures in EPR3 define a unique class of plant carbohydrate receptors

Exopolysaccharides (EPS) are perceived by legumes and regulate symbiosis with rhizobia. Here the authors describe the structure of the Lotus EPS receptor, EPR3 and show that it has atypical βαββ and βαβ folds that represent a structural signature for a unique class of EPS receptors in the plant kingdom.

Jaslyn E. M. M. Wong
Kira Gysel
Kasper R. Andersen
ResearchOpen Access30 Jul 2020
Nature Communications

Volume: 11, P: 1-8
Structural insights into Frizzled3 through nanobody modulators

The Wnt receptor Frizzled (FZD) family is crucial for both canonical (β-catenin dependent) and non-canonical (β-catenin independent) Wnt signalling. Here, the authors present the structures of FZD3 in complex with extracellular and intracellular binding nanobodies (Nbs), elucidating extracellular and intracellular interaction surfaces of functional and potentially therapeutic significance.

James Hillier
Yuguang Zhao
E. Yvonne Jones
ResearchOpen Access22 Aug 2024
Nature Communications

Volume: 15, P: 1-13
mTOR dysregulation induces IL-6 and paracrine AT2 cell senescence impeding lung repair in lymphangioleiomyomatosis

Lymphangioleiomyomatosis (LAM) is a rare disease in women where TSC2 deficient mTOR signalling aberrant LAM cells and fibroblasts form nodules causing lung cysts and respiratory failure. Here the authors examine how mTOR dependent IL-6 causes senescence in alveolar type 2 cells which may result in impaired lung repair.

Roya Babaei-Jadidi
Debbie Clements
Simon R. Johnson
ResearchOpen Access09 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Gold 2023: Highlights for primary care

Alvar Agustí
Antoni Sisó-Almirall
Jadwiga A. Wedzicha
Comments & OpinionOpen Access31 Jul 2023
npj Primary Care Respiratory Medicine

Volume: 33, P: 1-10
Medicarpin, a legume phytoalexin sensitizes myeloid leukemia cells to TRAIL-induced apoptosis through the induction of DR5 and activation of the ROS-JNK-CHOP pathway

R Trivedi
R Maurya
D P Mishra
ResearchOpen Access16 Oct 2014
Cell Death & Disease

Volume: 5, P: e1465
Neuro-ophthalmic findings in botulism type B

P R Simcock
S Kelleher
J A Dunne
Research01 Nov 1994
Eye

Volume: 8, P: 646-648
Pyrexia in hospitalised spinal cord injury patients

P S S Beraldo
E G C Neves
M R B Alencar
Research01 Mar 1993
Spinal Cord

Volume: 31, P: 186-191
Pulmonary embolism manifesting as acute disturbances of behavior in patients with spinal cord injury

J H Frisbie
G V R K Sharma
Research01 Aug 1994
Spinal Cord

Volume: 32, P: 570-572
Uncovering patterns of inhaler technique and reliever use: the value of objective, personalized data from a digital inhaler

Mark L. Levy
Janwillem W. H. Kocks
Henry Chrystyn
ResearchOpen Access20 Aug 2024
npj Primary Care Respiratory Medicine

Volume: 34, P: 1-11
Cryo-EM structures of type IV pili complexed with nanobodies reveal immune escape mechanisms

Bacterial type IV pili are filamentous cell surface structures and candidate targets for vaccine development. Here, authors determine how antibodies interact with pili at the structural level providing insight into immune escape mechanisms and potential countermeasures.

David Fernandez-Martinez
Youxin Kong
Guillaume Duménil
ResearchOpen Access18 Mar 2024
Nature Communications

Volume: 15, P: 1-15
Energy expenditure and body temperature variations in llamas living in the High Andes of Peru

Alexander Riek
Anna Stölzl
Martina Gerken
ResearchOpen Access11 Mar 2019
Scientific Reports

Volume: 9, P: 1-11
RNA methyltransferase SPOUT1/CENP-32 links mitotic spindle organization with the neurodevelopmental disorder SpADMiSS

The RNA methyltransferase activity of SPOUT1/CENP-32 is crucial for accurate mitotic spindle organization. Here, the authors describe a neurodevelopmental disorder caused by bi-allelic pathogenic SPOUT1 variants with reduced activity and compromised function in spindle organization.

Avinash V. Dharmadhikari
Maria Alba Abad
Jun Liao
ResearchOpen Access17 Feb 2025
Nature Communications

Volume: 16, P: 1-24
MR-1 blocks the megakaryocytic differentiation and transition of CML from chronic phase to blast crisis through MEK dephosphorylation

W Zhao
H He
R-g Shao
ResearchOpen Access29 Mar 2013
Blood Cancer Journal

Volume: 3, P: e107
A single-domain bispecific antibody targeting CD1d and the NKT T-cell receptor induces a potent antitumor response

Rossjohn, van der Vliet and colleagues develop single-domain antibodies binding composite CD1d and NKT T-cell receptor antigens, inducing specific antitumor immune subsets.

Roeland Lameris
Adam Shahine
Hans J. van der Vliet
Research14 Sept 2020
Nature Cancer

Volume: 1, P: 1054-1065
Structure of the G protein chaperone and guanine nucleotide exchange factor Ric-8A bound to Gαi1

Ric-8A is guanine nucleotide exchange factor (GEF) that also acts as a folding chaperone for its Gα subunit. Here, the authors present the structure of Ric-8A bound to nucleotide-free Gαi1, revealing the mechanism by which Ric-8A exerts both GEF and chaperone activity.

Levi J. McClelland
Kaiming Zhang
Stephen R. Sprang
ResearchOpen Access26 Feb 2020
Nature Communications

Volume: 11, P: 1-10
Human level information extraction from clinical reports with finetuned language models

Longchao Liu
Long Lian
Adam Yala
ResearchOpen Access24 Nov 2025
Scientific Reports

Volume: 15, P: 1-12
Fusion with political leaders predicts willingness to persecute immigrants and political opponents

From the 2016 US presidential election and into 2019, Kunst and colleagues show that a visceral feeling of oneness (that is, psychological fusion) with a political leader can fuel partisans’ willingness to actively participate in political violence.

Jonas R. Kunst
John F. Dovidio
Lotte Thomsen
Research02 Sept 2019
Nature Human Behaviour

Volume: 3, P: 1180-1189
Magnetic resonance mapping demonstrates benefits of VEGF–induced myocardial angiogenesis

Justin D. Pearlman
Mark G. Hibberd
Michael Simons
Research01 Oct 1995
Nature Medicine

Volume: 1, P: 1085-1089
Synergistic H&E and IHC image analysis by AI predicts cancer biomarkers and survival outcomes in colorectal and breast cancer

Cheng and Lama et al. developed a synergistic dual-modality AI framework for prediction of MMRd/MSI-High status in colorectal cancer and PD-L1 status in breast cancer. Their model, which analyzes H&E and IHC images, achieves clinical grade performance and identifies patients with improved outcomes on pembrolizumab immunotherapy.

Yating Cheng
Norsang Lama
George W. Sledge
ResearchOpen Access01 Aug 2025
Communications Medicine

Volume: 5, P: 1-15
A call to action for the evolving field of cardio-oncology

Heart failure and cancer share risk factors and biological pathways, yet their interplay remains underexplored. This Comment calls for coordinated research, precision medicine approaches and policy changes to advance the emerging field of cardio-oncology.

Reza Parvan
Joseph Pierre AbouMsallem
Rudolf A. de Boer
Comments & Opinion12 Nov 2025
Nature Cardiovascular Research

Volume: 4, P: 1441-1446
The effect of umeclidinium added to inhaled corticosteroid/long-acting β₂-agonist in patients with symptomatic COPD: a randomised, double-blind, parallel-group study

Ana R Sousa
John H Riley
William A Fahy
ResearchOpen Access23 Jun 2016
npj Primary Care Respiratory Medicine

Volume: 26, P: 1-7
An upper limit on the EUV flux from HD192273

Don C. Barry
Bill R. Sandel
A. Lyle Broadfoot
Research22 May 1980
Nature

Volume: 285, P: 210-211
Properly formed but improperly localized synaptic specializations in the absence of laminin α4

Bruce L. Patton
Jeanette M. Cunningham
Joshua R. Sanes
Research01 Jun 2001
Nature Neuroscience

Volume: 4, P: 597-604
A test of the lateral semicircular canal correlation to head posture, diet and other biological traits in “ungulate” mammals

J. Benoit
L. J. Legendre
P. R. Manger
ResearchOpen Access11 Nov 2020
Scientific Reports

Volume: 10, P: 1-22
The contribution of an asthma diagnostic consultation service in obtaining an accurate asthma diagnosis for primary care patients: results of a real-life study

R. M. E. Gillis
W. van Litsenburg
F. W. Smeenk
ResearchOpen Access19 May 2017
npj Primary Care Respiratory Medicine

Volume: 27, P: 1-5
A conserved immunogenic and vulnerable site on the coronavirus spike protein delineated by cross-reactive monoclonal antibodies

Here, the authors report the isolation and characterization of two human monoclonal antibodies (mAbs) from immunized mice with trimeric spike ectodomains of three human betacoronaviruses HCoV-OC43, SARS-CoV and MERSCoV, and show that while exhibiting cross-reactivity, the mAbs only neutralize MERS-CoV but not SARS-CoV nor SARS-CoV-2, likely due to the subtle epitope differences in the spike S2 fusion subunit.

Chunyan Wang
Rien van Haperen
Berend-Jan Bosch
ResearchOpen Access17 Mar 2021
Nature Communications

Volume: 12, P: 1-15
Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation

Deubiquitinase OTULIN targets linear (M1-linked) ubiquitin chain patches on cytosolic Salmonella Typhimurium to modulate NEMO, IKKα/IKKβ and NF-ĸB signalling and regulate secretion of pro-inflammatory cytokines and bacterial proliferation.

Sjoerd J. L. van Wijk
Franziska Fricke
Ivan Dikic
Research08 May 2017
Nature Microbiology

Volume: 2, P: 1-10
Evidence for lateral gene transfer between Archaea and Bacteria from genome sequence of Thermotoga maritima

Karen E. Nelson
Rebecca A. Clayton
Claire M. Fraser
Research27 May 1999
Nature

Volume: 399, P: 323-329
Missense mutation in flavin-containing mono-oxygenase 3 gene, FMO3, underlies fish-odour syndrome

Colin T. Dolphin
Azara Janmohamed
lan R. Phillips
Research01 Dec 1997
Nature Genetics

Volume: 17, P: 491-494

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