Nature Search

Effector T lymphocyte line cells migrate to the thymus and persist there

Yaakov Naparstek
Joseph Holoshitz
Irun R. Cohen
Research18 Nov 1982
Nature

Volume: 300, P: 262-264
Suppressive vaccination with DNA encoding a variable region gene of the T–cell receptor prevents autoimmune encephalomyelitis and activates Th2 immunity

Ari Waisman
Pedro J. Ruiz
Lawrence Steinman
Research01 Aug 1996
Nature Medicine

Volume: 2, P: 899-905
PSCA-targeted BPX-601 CAR T cells with pharmacological activation by rimiducid in metastatic pancreatic and prostate cancer: a phase 1 dose escalation trial

The success of CAR T cell therapies against solid tumors remains limited. Here the authors report the results of a phase 1 trial of PSCA-directed autologous CAR-T cells with pharmacological activation by rimiducid in patients with metastatic pancreatic or prostate cancer.

Mark N. Stein
Ecaterina E. Dumbrava
Carlos R. Becerra
ResearchOpen Access30 Dec 2024
Nature Communications

Volume: 15, P: 1-13
Function recovery following neural transplantation of embryonic septal nuclei in adult rats with septohippocampal lesions

Walter C. Low
Peter R. Lewis
Ulf Stenevi
Research18 Nov 1982
Nature

Volume: 300, P: 260-262
Reply to ‘Physical limitations on broadband invisibility based on fast-light media’

K. L. Tsakmakidis
O. Reshef
H. Altug
ResearchOpen Access24 May 2021
Nature Communications

Volume: 12, P: 1-3
Fatty Acids of Phospholipids in Human Neonatal Lung Surfactant

Christine E Parkinson
David R Harvey
J Pryse-Davies
Research01 Jun 1977
Pediatric Research

Volume: 11, P: 723-727
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis

Fibroblasts play critical roles in tissue homeostasis, but in pathologic states they can drive fibrosis, inflammation, and tissue destruction. Here, Faust et al. find that healthy human synovial fibroblasts under the influence of adjacent adipocytes have altered lipid metabolism driven by cortisol signaling. Both adipocytes and these characteristics are lost in inflammatory arthritis.

Heather J. Faust
Tan-Yun Cheng
Michael B. Brenner
ResearchOpen Access14 Nov 2024
Nature Communications

Volume: 15, P: 1-20
Granzyme K activates the entire complement cascade

A study finds that a protease called granzyme K can activate the entire complement cascade, explaining how it can drive destructive inflammation in inflammatory diseases such as rheumatoid arthritis.

Carlos A. Donado
Erin Theisen
Michael B. Brenner
Research06 Feb 2025
Nature

Volume: 641, P: 211-221
Ultrabroadband 3D invisibility with fast-light cloaks

Three-dimensional invisibility cloaks are either limited in bandwidth or disregard the phase of the impinging wave or work only in specific directions. Here, the authors report that these restrictions can be lifted by using cloaks made of fast-light media where the wave group velocity is larger than the speed of light in vacuum.

K. L. Tsakmakidis
O. Reshef
H. Altug
ResearchOpen Access24 Oct 2019
Nature Communications

Volume: 10, P: 1-7
Interferon subverts an AHR–JUN axis to promote CXCL13⁺ T cells in lupus

Insufficient AHR activation has been suggested in SLE, and augmenting AHR activation therapeutically may prevent CXCL13⁺ T_PH/T_FH differentiation and the subsequent recruitment of B cells and formation of lymphoid aggregates in inflamed tissues.

Calvin Law
Vanessa Sue Wacleche
Deepak A. Rao
Research10 Jul 2024
Nature

Volume: 631, P: 857-866
Pyruvate Carboxylase Deficiency: A Benign Variant with Normal Development

R N Van Coster
P M Fernhoff
D C De Vivo
Research01 Jul 1991
Pediatric Research

Volume: 30, P: 1-4
Antibodies to Human HSP60 in Patients with Juvenile Chronic Arthritis, Diabetes Mellitus, and Cystic Fibrosis

E R de Graeff-Meeder
G T Rijkers
B J M Zegers
Research01 Oct 1993
Pediatric Research

Volume: 34, P: 424-428
Induction of Cytosolic Phosphoenolpyruvate Carboxykinase in the Ovine Fetal Liver by Chronic Fetal Hypoglycemia and Hypoinsulinemia

Michael R Narkewicz
Thomas D Carver
William W Hay Jr
Research01 May 1993
Pediatric Research

Volume: 33, P: 493-496
How to organize an online conference

The first online-only meeting in photonics, held on January 13th 2020, was a resounding success, with 1100 researchers participating remotely to discuss the latest advances in photonics. Here, the organizers share their tips and advice on how to organize an online conference.

Orad Reshef
Igor Aharonovich
Riccardo Sapienza
Comments & Opinion18 Mar 2020
Nature Reviews Materials

Volume: 5, P: 253-256
Detecting genome-wide directional effects of transcription factor binding on polygenic disease risk

Signed linkage disequilibrium profile regression is a new method for detecting directional effects of genomic annotations on disease risk. The results implicate new causal disease genes and can suggest mechanisms underlying the effects of causal genes on disease.

Yakir A. Reshef
Hilary K. Finucane
Alkes L Price
Research03 Sept 2018
Nature Genetics

Volume: 50, P: 1483-1493
Bacterial profiling of White Plague Disease in a comparative coral species framework

Cornelia Roder
Chatchanit Arif
Christian R Voolstra
ResearchOpen Access08 Aug 2013
The ISME Journal

Volume: 8, P: 31-39
Leveraging supervised learning for functionally informed fine-mapping of cis-eQTLs identifies an additional 20,913 putative causal eQTLs

Finding causal variants and genes from GWAS loci results remains a challenge. Here, the authors train a model to predict if a variant affects nearby gene expression, and apply the method to identify new possible causal eQTLs and mechanisms of GWAS loci.

Qingbo S. Wang
David R. Kelley
Hilary K. Finucane
ResearchOpen Access07 Jun 2021
Nature Communications

Volume: 12, P: 1-11
Pyruvate Carboxylase Deficiency and Lactic Acidosis in a Retarded Child without Leigh's Disease

Beth M Atkin
Neil R M Buist
Betty Q Banker
Research01 Feb 1979
Pediatric Research

Volume: 13, P: 109-116
Mapping the dynamic genetic regulatory architecture of HLA genes at single-cell resolution

scHLApers is an analysis pipeline that quantifies single-cell expression of HLA genes using a personalized genomic reference. Mapping of HLA expression quantitative trait loci at single-cell resolution identifies dynamic effects across cell states.

Joyce B. Kang
Amber Z. Shen
Soumya Raychaudhuri
Research30 Nov 2023
Nature Genetics

Volume: 55, P: 2255-2268
A framework for EO-based National Agricultural Monitoring (EO-NAM) for the African Context

Effective agriculture monitoring is vital for food security and achieving UN Sustainable Development Goal 2: Zero Hunger. Earth-observations (EO) offer unparalleled potential for scalable data, yet many developing nations, particularly in Africa, face challenges due to limited investments in human capacity and technology. We present a phased framework for EO-based agriculture monitoring systems, emphasizing national commitment and leveraging existing structures for long-term sustainability and adopting and adapting future advancements.

Catherine Nakalembe
Hannah R. Kerner
Inbal Becker-Reshef
Comments & OpinionOpen Access04 Aug 2025
npj Sustainable Agriculture

Volume: 3, P: 1-8
Publisher Correction: Interferon subverts an AHR–JUN axis to promote CXCL13⁺ T cells in lupus

Calvin Law
Vanessa Sue Wacleche
Deepak A. Rao
Amendments and Corrections26 Jul 2024
Nature

Volume: 632, P: E6
Evidence for phosphonate usage in the coral holobiont

S Thomas
H Burdett
J A Gilbert
Research03 Dec 2009
The ISME Journal

Volume: 4, P: 459-461
Shifts in bacterial communities of two caribbean reef-building coral species affected by white plague disease

Anny Cárdenas
Luis M Rodriguez-R
Catalina Arévalo-Ferro
Research29 Sept 2011
The ISME Journal

Volume: 6, P: 502-512
Near- to long-term measures to stabilize global wheat supplies and food security

The Ukraine–Russia war will impact global food security over months if not years. In the wake of COVID-19 and in the face of increasing climate change, we propose responses to a multi-layered global food crisis that mitigate near-term food security risks, stabilize wheat supplies and transition towards long-term agri-food system resilience.

Alison R. Bentley
Jason Donovan
Bram Govaerts
Comments & Opinion19 Jul 2022
Nature Food

Volume: 3, P: 483-486
Heritability enrichment of specifically expressed genes identifies disease-relevant tissues and cell types

A new method tests whether disease heritability is enriched near genes with high tissue-specific expression. The authors use gene expression data together with GWAS summary statistics for 48 diseases and traits to identify disease-relevant tissues.

Hilary K. Finucane
Yakir A. Reshef
Alkes L. Price
Research09 Apr 2018
Nature Genetics

Volume: 50, P: 621-629
The gold ticket to achiral WS₂ nanotubes

Multiwalled WS₂ and WSe₂ nanotubes with predominantly a single chiral angle are produced in a chemical vapour deposition reactor using gold nanoparticles as a catalyst. This strategy paves the way for the growth of transition metal dichalcogenide nanotubes with controllable structures for further exploring their physical properties and potential applications.

M. Bar-Saden
R. Tenne
News & Views13 Jul 2023
Nature Materials

Volume: 23, P: 310-311
Immune-centric network of cytokines and cells in disease context identified by computational mining of PubMed

Interactions between hundreds of immune cells and cytokines in disease are mined from PubMed.

Ksenya Kveler
Elina Starosvetsky
Shai S Shen-Orr
Research18 Jun 2018
Nature Biotechnology

Volume: 36, P: 651-659
Reference-based phasing using the Haplotype Reference Consortium panel

Po-Ru Loh, Alkes Price and colleagues present Eagle2, a reference-based phasing algorithm that allows for highly accurate and efficient phasing of genotypes across a broad range of cohort sizes. They demonstrate an approximately 10% improvement in accuracy and 20% improvement in speed compared to a competing method, SHAPEIT2.

Po-Ru Loh
Petr Danecek
Alkes L Price
Research03 Oct 2016
Nature Genetics

Volume: 48, P: 1443-1448
Partitioning heritability by functional annotation using genome-wide association summary statistics

Hilary Finucane, Brendan Bulik-Sullivan, Benjamin Neale, Alkes Price and colleagues introduce a new method, called stratified LD score regression, for partitioning heritability by functional category using genome-wide association study summary statistics. They observe a substantial enrichment of heritability in conserved regions and illustrate how this approach can provide insights into the biological basis of disease and direction for functional follow-up.

Hilary K Finucane
Brendan Bulik-Sullivan
Alkes L Price
Research28 Sept 2015
Nature Genetics

Volume: 47, P: 1228-1235
Galectin-3 predicts acute GvHD and overall mortality post reduced intensity allo-HCT: a BMT-CTN biorepository study

Philip L. McCarthy
Kristopher M. Attwood
Hemn Mohammadpour
Research18 Dec 2023
Bone Marrow Transplantation

Volume: 59, P: 334-343
Differential specificity between closely related corals and abundant Endozoicomonas endosymbionts across global scales

Matthew J Neave
Rita Rachmawati
Christian R Voolstra
ResearchOpen Access08 Jul 2016
The ISME Journal

Volume: 11, P: 186-200
Single-cell analysis of experience-dependent transcriptomic states in the mouse visual cortex

Using single-cell RNA-sequencing, the authors record snapshots of the dynamic sensory-experience-dependent transcriptome across all cell types of the visual cortex in mice exposed to a light stimulus. The authors note diverse cell-type-specific programs in pyramidal neuron subtypes and robust non-neuronal responses that may regulate experience-dependent neurovascular coupling and myelination.

Sinisa Hrvatin
Daniel R. Hochbaum
Michael E. Greenberg
Research11 Dec 2017
Nature Neuroscience

Volume: 21, P: 120-129
The microbiome of coral surface mucus has a key role in mediating holobiont health and survival upon disturbance

Bettina Glasl
Gerhard J Herndl
Pedro R Frade
ResearchOpen Access08 Mar 2016
The ISME Journal

Volume: 10, P: 2280-2292
High levels of heterogeneity in diazotroph diversity and activity within a putative hotspot for marine nitrogen fixation

Lauren F Messer
Claire Mahaffey
Justin R Seymour
Research27 Nov 2015
The ISME Journal

Volume: 10, P: 1499-1513
Inorganic nanotubes and fullerene-like nanoparticles

R. Tenne
Reviews01 Nov 2006
Nature Nanotechnology

Volume: 1, P: 103-111
Higher tacrolimus concentrations early after transplant reduce the risk of acute GvHD in reduced-intensity allogeneic stem cell transplantation

A Ganetsky
A Shah
R Reshef
Research21 Dec 2015
Bone Marrow Transplantation

Volume: 51, P: 568-572
Inflammatory cytokine inhibition with combination daclizumab and infliximab for steroid-refractory acute GVHD

A Rager
N Frey
D L Porter
Research24 May 2010
Bone Marrow Transplantation

Volume: 46, P: 430-435
Imatinib mesylate (Gleevec) downregulates telomerase activity and inhibits proliferation in telomerase-expressing cell lines

O Uziel
E Fenig
M Lahav
ResearchOpen Access03 May 2005
British Journal of Cancer

Volume: 92, P: 1881-1891
Dynamic microglial alterations underlie stress-induced depressive-like behavior and suppressed neurogenesis

T Kreisel
M G Frank
R Yirmiya
Research17 Dec 2013
Molecular Psychiatry

Volume: 19, P: 699-709
GvHD after umbilical cord blood transplantation for acute leukemia: an analysis of risk factors and effect on outcomes

Y-B Chen
T Wang
C S Cutler
Research12 Dec 2016
Bone Marrow Transplantation

Volume: 52, P: 400-408
Allogeneic hematopoietic cell transplant for AML: no impact of pre-transplant extramedullary disease on outcome

S D Goyal
M-J Zhang
G L Uy
Research27 Apr 2015
Bone Marrow Transplantation

Volume: 50, P: 1057-1062
Reduced-intensity conditioned allogeneic SCT in adults with AML

R Reshef
D L Porter
Reviews02 Mar 2015
Bone Marrow Transplantation

Volume: 50, P: 759-769
Donor body mass index does not predict graft versus host disease following hematopoietic cell transplantation

Lucie M. Turcotte
Tao Wang
Michael R. Verneris
Correspondence30 Jan 2018
Bone Marrow Transplantation

Volume: 53, P: 932-937
High-dose corticosteroids with or without etanercept for the treatment of idiopathic pneumonia syndrome after allo-SCT

R Tizon
N Frey
D L Porter
Research06 Feb 2012
Bone Marrow Transplantation

Volume: 47, P: 1332-1337

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