Cardiac resynchronization can be a useful therapy for patients with heart failure and abnormal ventricular contraction. However, up to half of patients do not respond to therapy. In this Review, Vernooy and colleagues discuss the selection of patients, positioning of pacing leads, timing of pacing, and management of patients after device implantation to improve the outcomes from cardiac resynchronization therapy.
- Kevin Vernooy
- Caroline J. M. van Deursen
- Frits W. Prinzen