Piraino, Chen, Mereness et al use a salivary gland tissue chip for high-content radioprotective drug discovery. Three drugs are identified that exhibit higher potency and equivalent radioprotection to Amifostine, the only FDA approved drug that is rarely used clinically due to severe side effects and lack of efficacy.
- Lindsay R. Piraino
- Chiao Yun Chen
- Lisa A. DeLouise