Nature Search

Biosynthesis of the antibiotic nonribosomal peptide penicillin in baker’s yeast

Filamentous fungi are a valuable source of natural therapeutic products such as antibiotics. Here the authors engineer monocellularS. cerevisiaeto perform complex secondary metabolism typical of multicellular fungi in order to demonstrate biosynthesis and secretion of bioactive penicillin.

Ali R. Awan
Benjamin A. Blount
Tom Ellis
ResearchOpen Access04 May 2017
Nature Communications

Volume: 8, P: 1-8
Natural selection on body size and proportions in house sparrows

Robert C. Fleischer
Richard F. Johnston
Research19 Aug 1982
Nature

Volume: 298, P: 747-749
Trans-eQTL mapping prioritises USP18 as a negative regulator of interferon response at a lupus risk locus

Here the authors perform a trans expression quantitative trait locus meta-analysis study of over 3,700 people and link a USP18 variant to expression of 50 inflammation genes and lupus risk, highlighting how genetic regulation of immune responses drives autoimmune disease and informs new therapies.

Krista Freimann
Anneke Brümmer
Kaur Alasoo
ResearchOpen Access02 Oct 2025
Nature Communications

Volume: 16, P: 1-15
Native diversity buffers against severity of non-native tree invasions

Analysis combining multiple global tree databases reveals that whether a location is invaded by non-native tree species depends on anthropogenic factors, but the severity of the invasion depends on the native species diversity.

Camille S. Delavaux
Thomas W. Crowther
Daniel S. Maynard
ResearchOpen Access23 Aug 2023
Nature

Volume: 621, P: 773-781
Characterising acute and chronic care needs: insights from the Global Burden of Disease Study 2019

Chronic care manages long-term, progressive conditions, while acute care handles short-term ones. Here, authors show chronic conditions account for most of the global health burden, with 68% of DALYs and 93% of YLDs attributed to chronic care needs.

Cecilia Anza-Ramirez
J. Jaime Miranda
Yves Miel H. Zuniga
ResearchOpen Access07 May 2025
Nature Communications

Volume: 16, P: 1-36
Degradation of Tryptophan Messenger: Direction of in vivo Degradation of Tryptophan Messenger RNA–A Correction

DANIEL E. MORSE
RAYMOND MOSTELLER
CHARLES YANOFSKY
Research05 Jul 1969
Nature

Volume: 223, P: 40-43
Polygenic and developmental profiles of autism differ by age at diagnosis

A study of several longitudinal birth cohorts and cross-sectional cohorts finds only moderate overlap in genetic variants between autism that is diagnosed earlier and that diagnosed later, so they may represent aetiologically different conditions.

Xinhe Zhang
Jakob Grove
Varun Warrier
ResearchOpen Access01 Oct 2025
Nature

P: 1-12
Size Fractionation of Exponentially Growing Escherichia coli

HAIM MANOR
ROBERT HASELKORN
Research01 Jun 1967
Nature

Volume: 214, P: 983-986
A three-dimensional seismic image of the crust and upper mantle beneath the Kenya rift

W.Verney Green
Ulrich Achauer
Robert P. Meyer
Research21 Nov 1991
Nature

Volume: 354, P: 199-203
Computational design of sequence-specific DNA-binding proteins

The authors develop a computational method to design small DNA-binding proteins (DBPs) that target specific sequences. Designed DBPs show structural accuracy and function in both bacterial and mammalian cells for transcriptional regulation.

Cameron J. Glasscock
Robert J. Pecoraro
David Baker
ResearchOpen Access12 Sept 2025
Nature Structural & Molecular Biology

P: 1-10
PULMONARY May 17, 1973, 2:00 P.M. Continental Ballroom 6

Robert B Mellins
Research01 Apr 1973
Pediatric Research

Volume: 7, P: 59-168
A Cytological Study of the Neurones of Patella Vulgata by Light and Electron Microscopy

DENNIS LACY
ROBERT HORNE
Research03 Nov 1956
Nature

Volume: 178, P: 976-978
Direction of in vivo Degradation of a Messenger RNA

ROBERT F. BAKER
CHARLES YANOFSKY
Research06 Jul 1968
Nature

Volume: 219, P: 26-29
Calcium activation of the cortical reaction in sea urchin eggs

ROBERT S. ZUCKER
RICHARD A. STEINHARDT
Research28 Jun 1979
Nature

Volume: 279, P: 820
Measuring the semantic priming effect across many languages

In this Stage 2 Registered Report, Buchanan et al. show evidence confirming the phenomenon of semantic priming across speakers of 19 diverse languages.

Erin M. Buchanan
Kelly Cuccolo
Savannah C. Lewis
Research24 Sept 2025
Nature Human Behaviour

P: 1-20
Multispectral live-cell imaging with uncompromised spatiotemporal resolution

A tree-like arrangement of dichroic mirrors and multiple cameras coupled with an iterative spectral unmixing algorithm enables multispectral imaging of live cells in up to eight spectral channels with diffraction-limited spatial resolution and temporal resolution of 0.3 s for imaging a full cell volume.

Akaash Kumar
Kerrie E. McNally
James D. Manton
ResearchOpen Access08 Sept 2025
Nature Photonics

Volume: 19, P: 1146-1156
Application of Ablation Analysis to Stony Meteorites and the Tektite Problem

ERNST W. ADAMS
ROBERT M. HUFFAKER
Research31 Mar 1962
Nature

Volume: 193, P: 1249-1251
Earliest Homo debate

Andrew Hill
Steven Ward
Robert Drake
Research23 Jul 1992
Nature

Volume: 358, P: 290
Cell Metabolism During Melanophore Activity

MANFRED E. A. FUCHS
ROBERT G. A. LOTZ
Research01 Oct 1966
Nature

Volume: 212, P: 39-40
Population genomics of domestic and wild yeasts

David Carter
Gianni Liti
Edward Louis
ResearchOpen Access20 Jun 2008
Nature Precedings

P: 1
Effect of climate on traits of dominant and rare tree species in the world’s forests

Species’ traits and environmental conditions determine the abundance of tree species across the globe. Here, the authors find that dominant tree species are taller and have softer wood compared to rare species and that these trait differences are more strongly associated with temperature than water availability.

Iris Hordijk
Lourens Poorter
Thomas W. Crowther
ResearchOpen Access22 May 2025
Nature Communications

Volume: 16, P: 1-15
Inhibition of Interferon Action by p-Fluorophenylalanine

ROBERT M. FRIEDMAN
JOSEPH A. SONNABEND
Research25 Jul 1964
Nature

Volume: 203, P: 366-367
Cooperativity of folding of the apomyoglobin pH 4 intermediate studied by glycine and proline mutations

Yongzhang Luo
Michael S. Kay
Robert L. Baldwin
Research01 Nov 1997
Nature Structural Biology

Volume: 4, P: 925-930
Fur Seals from the Bering Sea breeding in California

RICHARD S. PETERSON
BURNEY J. LE BOEUF
ROBERT L. DELONG
Research31 Aug 1968
Nature

Volume: 219, P: 899-901
Colorimetric Detection of Penicillins and Cephalosporins on Paper

ROBERT THOMAS
Research16 Sept 1961
Nature

Volume: 191, P: 1161-1163
Leakage Current Rectification in the Squid Giant Axon

WILLIAM J. ADELMAN
ROBERT E. TAYLOR
Research03 Jun 1961
Nature

Volume: 190, P: 883-885
An analysis and evaluation of the WeFold collaborative for protein structure prediction and its pipelines in CASP11 and CASP12

Chen Keasar
Liam J. McGuffin
Silvia N. Crivelli
ResearchOpen Access02 Jul 2018
Scientific Reports

Volume: 8, P: 1-18
The BRIF (Bioresource Research Impact Factor) as a tool for improving bioresource sharing in biomedical research

Elena Bravo
Anne Cambon-Thomsen
Jane Carpenter
ResearchOpen Access04 Nov 2011
Nature Precedings

P: 1
Regulation of lipid saturation without sensing membrane fluidity

Cells maintain membrane fluidity by regulating lipid saturation, but the molecular mechanisms of this homeoviscous adaptation remain poorly understood. Here authors reconstituted the core machinery for regulating lipid saturation in baker’s yeast to directly characterize its response to defined membrane environments and uncover its mode-of-action.

Stephanie Ballweg
Erdinc Sezgin
Robert Ernst
ResearchOpen Access06 Feb 2020
Nature Communications

Volume: 11, P: 1-13
Physiological [Ca²⁺]_i level and pump-leak turnover in intact red cells measured using an incorporated Ca chelator

Virgilio L. Lew
Roger Y. Tsien
Robert M. Bookchin
Research01 Jul 1982
Nature

Volume: 298, P: 478-481
Biochemical Specification versus Specific Regrowth in the Innervation of Skin Grafts in Anurans

ROBERT E. BAKER
Research31 Mar 1972
Nature

Volume: 236, P: 235-237
Stable isotopes in a branching coral monitor seasonal temperature variation

Robert B. Dunbar
Gerard M. Wellington
Research08 Oct 1981
Nature

Volume: 293, P: 453-455
MR-link-2: pleiotropy robust cis Mendelian randomization validated in three independent reference datasets of causality

Mendelian randomization (MR) identifies causal relationships from observational data but has increased error rates when the genetic variants used as instruments come from a single region, a typical scenario when assessing molecular traits like protein or metabolite levels as risk factors. Here the authors introduce a single-region pleiotropy-robust MR method, validating the method on three ground truth sources, showing its capability to identify disease-causing molecular traits.

Adriaan van der Graaf
Robert Warmerdam
Zoltán Kutalik
ResearchOpen Access03 Jul 2025
Nature Communications

Volume: 16, P: 1-19
Parent Body Hypothesis for Origin of Tektites

ERNST W. ADAMS
ROBERT M. HUFFAKER
Research18 Aug 1962
Nature

Volume: 195, P: 681-684
Co-ordination Chemistry and Membrane Function with Particular Reference to the Synapse and Catecholamine Transport

JAMES W. MAAS
ROBERT W. COLBURN
Research01 Oct 1965
Nature

Volume: 208, P: 41-46
Reaction Kinetic Studies of The Antigen–Antibody Reaction

ROBERT P. TENGERDY
WILLIAM H. SMALL
Research14 May 1966
Nature

Volume: 210, P: 708-710
Ocean ridges in hot water

Robert J. Poreda
News & Views09 Aug 1990
Nature

Volume: 346, P: 516
Adenosine Triphosphate—Metal—Norepinephrine Ternary Complexes and Catecholamine Binding

ROBERT W. COLBURN
JAMES W. MAAS
Research01 Oct 1965
Nature

Volume: 208, P: 37-41
Endothelium-dependent relaxation in rat aorta may be mediated through cyclic GMP-dependent protein phosphorylation

Robert M. Rapoport
Martin B. Draznin
Ferid Murad
Research10 Nov 1983
Nature

Volume: 306, P: 174-176
Evidence for volcanic eruption on the southern Juan de Fuca ridge between 1981 and 1987

William W. Chadwick Jr
Robert W. Embley
Christopher G. Fox
Research04 Apr 1991
Nature

Volume: 350, P: 416-418
Position of regularly spaced single-stranded regions relative to 5-bromodeoxyuridine-sensitive sites in sea urchin morula DNA

STEVEN T. CASE
ROBERT F. BAKER
Research03 Jan 1975
Nature

Volume: 253, P: 64-66
Effect of 5-bromodeoxyuridine on the size distribution of DNAs isolated from sea urchin embryos

ROBERT F. BAKER
STEVEN T. CASE
Research24 May 1974
Nature

Volume: 249, P: 350-352
Chromosome 4q DNA rearrangements associated with facioscapulohumeral muscular dystrophy

Cisca Wijmenga
Jane E. Hewitt
Rune R. Frants
Research01 Sept 1992
Nature Genetics

Volume: 2, P: 26-30
Diminishing benefits of urban living for children and adolescents’ growth and development

The advantage of living in cities compared with rural areas with respect to height and BMI in children and adolescents has generally become smaller globally from 1990 to 2020, except in sub-Saharan Africa.

Anu Mishra
Bin Zhou
Majid Ezzati
ResearchOpen Access29 Mar 2023
Nature

Volume: 615, P: 874-883
Thrombin and epidermal growth factor become linked to cell surface receptors during mitogenic stimulation

JOFFRE B. BAKER
ROBERT L. SIMMER
DENNIS D. CUNNINGHAM
Research01 Apr 1979
Nature

Volume: 278, P: 743-745
Identification of functional non-coding variants associated with orofacial cleft

Non-syndromic orofacial cleft is a relatively common congenital anomaly. Many non-coding genetic variants are associated with this disorder but only a subset is functional. Here the authors use reporter assays and stem cells to reveal members of this subset.

Priyanka Kumari
Ryan Z. Friedman
Robert A. Cornell
ResearchOpen Access16 Jul 2025
Nature Communications

Volume: 16, P: 1-17
Human cryptochrome exhibits light-dependent magnetosensitivity

In animals, cryptochrome proteins are thought to be the detectors of the Earth's magnetic field, but humans have not been shown to posess mangetosensing capabilities. Foleyet al. demonstrate that the human cryptochrome protein, CRY2, when expressed in Drosophila melanogastercan mediate magnetoreception in a light-dependent manner.

Lauren E. Foley
Robert J. Gegear
Steven M. Reppert
ResearchOpen Access21 Jun 2011
Nature Communications

Volume: 2, P: 1-3
Versatile modes of peptide recognition by the AAA+ adaptor protein SspB

Igor Levchenko
Robert A Grant
Tania A Baker
Research08 May 2005
Nature Structural & Molecular Biology

Volume: 12, P: 520-525
Ultrastructure of Isolated Heavy Beef Heart Mitochondria revealed by the Freeze-etching Technique

WILLIAM J. VAIL
ROBERT K. RILEY
Research25 Jun 1971
Nature

Volume: 231, P: 525-527
Towards hybrid superlattices in graphene

The controllable modification of graphene by chemical functionalization can modulate its optical and electronic properties. Sunet al. devise a functionalisation-based method to pattern graphane/graphene superlattices within a single sheet of graphene.

Zhengzong Sun
Cary L. Pint
James M. Tour
Research29 Nov 2011
Nature Communications

Volume: 2, P: 1-5

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