Nature Search

Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads

A new mouse model of Spegβ deficiency shows that Spegα prevents the development of dilated cardiomyopathy and decreases atrophy and loss force generation in skeletal muscle. Speg-β interacts with Esd, Fsd2, and Cmya5 and stabilizes interactions among excitation-contraction coupling proteins in triads and dyads.

Chang Seok Lee
Sung Yun Jung
Susan L. Hamilton
ResearchOpen Access14 Sept 2023
Communications Biology

Volume: 6, P: 1-19
This ‘minor’ bird flu strain has potential to spark human pandemic

Experiments suggests H9N2 has adapted to human cells, but cases of person-to-person transmission haven’t been reported yet.

Rachel Fieldhouse
News27 Oct 2025
Nature
Biosafety of Non-Return Valves for Infusion Systems in Radiology

Marcela Padilha Facetto Azevedo
Rachel Maciel Monteiro
Evandro Watanabe
ResearchOpen Access12 Jun 2020
Scientific Reports

Volume: 10, P: 1-7
The unprecedented Pacific Northwest heatwave of June 2021

The 2021 unprecedented Pacific Northwest heatwave broke temperature records by extraordinary amounts. Impacts included hundreds of deaths, mass-mortalities of marine life, increased wildfires, reduced crop and fruit yields, and river flooding.

Rachel H. White
Sam Anderson
Greg West
ResearchOpen Access09 Feb 2023
Nature Communications

Volume: 14, P: 1-20
A unified metric of human immune health

A multimodal analysis of patients with 22 different immune-mediated monogenic diseases versus matched healthy controls leads to the development of the immune health metric, which could be implemented broadly to predict responses to aging, vaccination and other immune perturbations.

Rachel Sparks
Nicholas Rachmaninoff
John S. Tsang
Research03 Jul 2024
Nature Medicine

Volume: 30, P: 2461-2472
DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge

Accurate segmentation of ischemic stroke lesions from brain MRI is crucial for timely diagnosis and treatment planning. Here, the authors present DeepISLES, an AI ensemble for stroke MRI analysis that outperforms previous methods and matches expert radiologist performance in identifying stroke lesions.

Ezequiel de la Rosa
Mauricio Reyes
Benedikt Wiestler
ResearchOpen Access09 Aug 2025
Nature Communications

Volume: 16, P: 1-16
The impacts of expertise, conflict, and scientific literacy on trust and belief in scientific disagreements

Natasha van Antwerpen
Estelle B. Green
Rachel A. Searston
ResearchOpen Access07 Apr 2025
Scientific Reports

Volume: 15, P: 1-16
Control of Early Flame Kernel Growth by Multi-Wavelength Laser Pulses for Enhanced Ignition

Ciprian Dumitrache
Rachel VanOsdol
Azer P. Yalin
ResearchOpen Access31 Aug 2017
Scientific Reports

Volume: 7, P: 1-8
Quantitative Measurement of “Natural” and Immunization-induced Haemophilus influenzas type b Capsular Polysaccharide Antibodies

John B Robbins
J C Parke Jr.
John K Whisnant
Research01 Mar 1973
Pediatric Research

Volume: 7, P: 103-110
Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19

Immune responses to influenza vaccination are affected by previous mild COVID-19 in a sex-dimorphic manner.

Rachel Sparks
William W. Lau
John S. Tsang
Research04 Jan 2023
Nature

Volume: 614, P: 752-761
Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP)

ABP profiling identifies uncharacterized S. aureus serine hydrolases, including the surface-localized FphB, which processes lipid ester substrates and is required for infection in vivo. An FphB inhibitor reduces in vivo bacterial load.

Christian S. Lentz
Jessica R. Sheldon
Matthew Bogyo
Research16 May 2018
Nature Chemical Biology

Volume: 14, P: 609-617
Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus

Simultaneous single-cell protein and transcriptome analysis identifies a baseline immune circuit associated with antibody responses to vaccination in healthy individuals and the severity of disease flares in patients with a subtype of systemic lupus erythematosus.

Yuri Kotliarov
Rachel Sparks
John S. Tsang
Research24 Feb 2020
Nature Medicine

Volume: 26, P: 618-629
The first billion years according to JWST

The infrared view of JWST has opened up the early Universe to study. This Perspective summarizes the key developments in our understanding of the high-redshift Universe from the first 18 months of JWST observations.

Angela Adamo
Hakim Atek
Antonella Nota
Reviews08 Aug 2025
Nature Astronomy

Volume: 9, P: 1134-1147
Lasers for engine ignition

The pollutant emissions and high-energy consumption of combustion engines using conventional spark plugs have long been serious environmental problems. Now, it has been demonstrated that lasers can provide a feasible green alternative. Duncan Graham-Rowe reports.

Duncan Graham-Rowe
Rachel Won
Comments & Opinion01 Sept 2008
Nature Photonics

Volume: 2, P: 515-517
Cells of the human intestinal tract mapped across space and time

Cells from embryonic, fetal, paediatric and adult human intestinal tissue are analysed at different locations along the intestinal tract to construct a single-cell atlas of the developing and adult human intestinal tract, encompassing all cell lineages.

Rasa Elmentaite
Natsuhiko Kumasaka
Sarah A. Teichmann
ResearchOpen Access08 Sept 2021
Nature

Volume: 597, P: 250-255
Out-of-Sample Extrapolation utilizing Semi-Supervised Manifold Learning (OSE-SSL): Content Based Image Retrieval for Histopathology Images

Rachel Sparks
Anant Madabhushi
ResearchOpen Access06 Jun 2016
Scientific Reports

Volume: 6, P: 1-15
Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

Coupling ultrasound-triggered microbubble destruction with antibiotics in diluted synovial fluid leads to the effective clearance of S. aureus in models of septic arthritis

Neil Zhao
Dylan Curry
Thomas P. Schaer
ResearchOpen Access17 Apr 2023
Communications Biology

Volume: 6, P: 1-11
Solid-phase asymmetric synthesis using a polymer-supported chiral Evans'-type oxazolidin-2-one

Rachel Green
Jennifer Peed
Steven D Bull
Protocols12 Sept 2013
Nature Protocols

Volume: 8, P: 1890-1906
Scoring disease in an animal model of multiple sclerosis using a novel infrared-based automated activity-monitoring system

Shailesh K. Shahi
Samantha N. Freedman
Ashutosh K. Mangalam
ResearchOpen Access16 Dec 2019
Scientific Reports

Volume: 9, P: 1-11
Publisher under fire for fake article webpages

'Trap’ URLs can help publishers to catch automated downloading, but critics say that the approach is clumsy.

Rachel Becker
Research Highlights29 Jun 2016
Nature

Volume: 535, P: 11
A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy

Carolina Mantilla-Rojas
Ming Yu
David W. Threadgill
Research25 Mar 2021
Oncogene

Volume: 40, P: 3047-3059
Additional α-glucosidase inhibitors from Malbranchea flavorosea (Leotiomycetes, Ascomycota)

Daniela Rebollar-Ramos
Martha L. Macías-Ruvalcaba
Rachel Mata
Research17 Jul 2018
The Journal of Antibiotics

Volume: 71, P: 862-871
A crowdsourcing approach for reusing and meta-analyzing gene expression data

Naisha Shah
Yongjian Guo
John S Tsang
CorrespondenceOpen Access20 Jun 2016
Nature Biotechnology

Volume: 34, P: 803-806
Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of Haemophilus influenzae

Alistair Harrison
Rachael L. Hardison
Kevin M. Mason
ResearchOpen Access05 Nov 2019
npj Biofilms and Microbiomes

Volume: 5, P: 1-14
Elucidation of glutamine lipid biosynthesis in marine bacteria reveals its importance under phosphorus deplete growth in Rhodobacteraceae

Alastair F. Smith
Branko Rihtman
Yin Chen
ResearchOpen Access14 Aug 2018
The ISME Journal

Volume: 13, P: 39-49
Diagnostic yield of pediatric and prenatal exome sequencing in a diverse population

Anne Slavotinek
Shannon Rego
Mary E. Norton
ResearchOpen Access26 May 2023
npj Genomic Medicine

Volume: 8, P: 1-10
Comparison of robotic and manual implantation of intracerebral electrodes: a single-centre, single-blinded, randomised controlled trial

Vejay N. Vakharia
Roman Rodionov
John S. Duncan
ResearchOpen Access24 Aug 2021
Scientific Reports

Volume: 11, P: 1-10
Effects of ophidiomycosis on movement, survival, and reproduction of eastern foxsnakes (Pantherophis vulpinus)

Rachel M. Dillon
James E. Paterson
Christina M. Davy
ResearchOpen Access28 Feb 2024
Scientific Reports

Volume: 14, P: 1-10
Human mid-trimester amniotic fluid (stem) cells lack expression of the pluripotency marker OCT4A

Filipa Vlahova
Kate E. Hawkins
Pascale V. Guillot
ResearchOpen Access31 May 2019
Scientific Reports

Volume: 9, P: 1-15
Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

Mustafa M. Munye
Aristides D. Tagalakis
Stephen L. Hart
ResearchOpen Access15 Mar 2016
Scientific Reports

Volume: 6, P: 1-11
Author Correction: Diagnostic yield of pediatric and prenatal exome sequencing in a diverse population

Anne Slavotinek
Shannon Rego
Mary E. Norton
Amendments and CorrectionsOpen Access23 Oct 2023
npj Genomic Medicine

Volume: 8, P: 1

Search

Speg interactions that regulate the stability of excitation-contraction coupling protein complexes in triads and dyads

This ‘minor’ bird flu strain has potential to spark human pandemic

Biosafety of Non-Return Valves for Infusion Systems in Radiology

The unprecedented Pacific Northwest heatwave of June 2021

A unified metric of human immune health

DeepISLES: a clinically validated ischemic stroke segmentation model from the ISLES'22 challenge

The impacts of expertise, conflict, and scientific literacy on trust and belief in scientific disagreements

Control of Early Flame Kernel Growth by Multi-Wavelength Laser Pulses for Enhanced Ignition

Quantitative Measurement of “Natural” and Immunization-induced Haemophilus influenzas type b Capsular Polysaccharide Antibodies

Influenza vaccination reveals sex dimorphic imprints of prior mild COVID-19

Identification of a S. aureus virulence factor by activity-based protein profiling (ABPP)

Broad immune activation underlies shared set point signatures for vaccine responsiveness in healthy individuals and disease activity in patients with lupus

The first billion years according to JWST

Lasers for engine ignition

Cells of the human intestinal tract mapped across space and time

Out-of-Sample Extrapolation utilizing Semi-Supervised Manifold Learning (OSE-SSL): Content Based Image Retrieval for Histopathology Images

Microbubble cavitation restores Staphylococcus aureus antibiotic susceptibility in vitro and in a septic arthritis model

Solid-phase asymmetric synthesis using a polymer-supported chiral Evans'-type oxazolidin-2-one

Scoring disease in an animal model of multiple sclerosis using a novel infrared-based automated activity-monitoring system

Publisher under fire for fake article webpages

A molecular subtype of colorectal cancers initiates independently of epidermal growth factor receptor and has an accelerated growth rate mediated by IL10-dependent anergy

Additional α-glucosidase inhibitors from Malbranchea flavorosea (Leotiomycetes, Ascomycota)

A crowdsourcing approach for reusing and meta-analyzing gene expression data

Reprioritization of biofilm metabolism is associated with nutrient adaptation and long-term survival of Haemophilus influenzae

Elucidation of glutamine lipid biosynthesis in marine bacteria reveals its importance under phosphorus deplete growth in Rhodobacteraceae

Diagnostic yield of pediatric and prenatal exome sequencing in a diverse population

Comparison of robotic and manual implantation of intracerebral electrodes: a single-centre, single-blinded, randomised controlled trial

Effects of ophidiomycosis on movement, survival, and reproduction of eastern foxsnakes (Pantherophis vulpinus)

Human mid-trimester amniotic fluid (stem) cells lack expression of the pluripotency marker OCT4A

Minicircle DNA Provides Enhanced and Prolonged Transgene Expression Following Airway Gene Transfer

Author Correction: Diagnostic yield of pediatric and prenatal exome sequencing in a diverse population

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