Nature Search

The AMBRA1 E3 ligase adaptor regulates the stability of cyclin D

AMBRA1 is the main regulator of the degradation of D-type cyclins, and loss of AMBRA1 promotes cell proliferation and tumour growth, and reduces the sensitivity of cancer cells to inhibition of CDK4 and CDK6.

Andrea C. Chaikovsky
Chuan Li
Julien Sage
Research14 Apr 2021
Nature

Volume: 592, P: 794-798
Corrigendum: Genome-wide association study of esophageal squamous cell carcinoma in Chinese subjects identifies susceptibility loci at PLCE1 and C20orf54

Li-Dong Wang
Fu-You Zhou
Xue-Jun Zhang
Amendments and Corrections01 Sept 2014
Nature Genetics

Volume: 46, P: 1041
Mouse strain differences in SSRI sensitivity correlate with serotonin transporter binding and function

Zeng-liang Jin
Xiao-Fei Chen
Yun-Feng Li
ResearchOpen Access17 Aug 2017
Scientific Reports

Volume: 7, P: 1-10
PKCα induces differentiation through ERK1/2 phosphorylation in mouse keratinocytes

Haeng Ran Seo
Yoo-Wook Kwan
Yun-Sil Lee
ResearchOpen Access01 Aug 2004
Experimental & Molecular Medicine

Volume: 36, P: 292-299
Author Correction: Mapping global lake dynamics reveals the emerging roles of small lakes

Xuehui Pi
Qiuqi Luo
Brett A. Bryan
Amendments and CorrectionsOpen Access25 Oct 2022
Nature Communications

Volume: 13, P: 1
An IgM-like inhalable ACE2 fusion protein broadly neutralizes SARS-CoV-2 variants

In this study, the authors report the development of an inhalable IgM-like ACE2 and show that it broadly neutralizes SARS-CoV-2 variants, lowers viral loads and lung pathology in hamsters when administered early, and has good safety profiles in rats and monkeys.

Juan Liu
Fengfeng Mao
Wenhui Li
ResearchOpen Access25 Aug 2023
Nature Communications

Volume: 14, P: 1-18
The engineering of TBBPA-degrading synthetic microbiomes with integrated strategies

Tong Wu
Sheng-Zhi Guo
Shuang-Jiang Liu
ResearchOpen Access19 Jul 2025
npj Biofilms and Microbiomes

Volume: 11, P: 1-12
Host-mediated ubiquitination of a mycobacterial protein suppresses immunity

Mycobacterium tuberculosis suppresses the production of inflammatory cytokines by host cells through the host-mediated ubiquitination of a mycobacterial protein, enhancing the interaction of a host signalling inhibitor with another signalling molecule.

Lin Wang
Juehui Wu
Baoxue Ge
Research15 Jan 2020
Nature

Volume: 577, P: 682-688
TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism

The PI3K/AKT signalling pathway regulates cancer metabolism. Here, the authors show a reciprocal positive feedback crosstalk between the PI3K/AKT and pentose phosphate pathway which promotes tumourigenesis.

Jie Cheng
Yan Huang
Hong Wu
ResearchOpen Access20 Apr 2020
Nature Communications

Volume: 11, P: 1-16
A Bayesian framework that integrates multi-omics data and gene networks predicts risk genes from schizophrenia GWAS data

Wang et al. present a computational framework integrating multi-omics data to infer key schizophrenia risk genes from GWAS data. These genes are predominantly expressed in the developing brain and are enriched for targets of approved drugs.

Quan Wang
Rui Chen
Bingshan Li
Research15 Apr 2019
Nature Neuroscience

Volume: 22, P: 691-699
Precise control of SCRaMbLE in synthetic haploid and diploid yeast

The SCRaMbLE system integrated into Sc2.0’s synthetic yeast chromosome project allows rapid strain evolution. Here the authors use a genetic logic gate to control induction of recombination in a haploid and diploid yeast carrying synthetic chromosomes.

Bin Jia
Yi Wu
Ying-Jin Yuan
ResearchOpen Access22 May 2018
Nature Communications

Volume: 9, P: 1-13
Naringin mitigates experimental autoimmune prostatitis by modulating oxidative stress and the NLRP3 inflammasome via the PPAR-γ/NF-κB pathway

Wang Zhou
Xi-Ran Zhang
Chao-Xue Zhang
ResearchOpen Access01 Jul 2025
Scientific Reports

Volume: 15, P: 1-16
Dosimetric and radiobiological evaluation of stereotactic radiosurgery using volumetric modulated arc therapy and dynamic conformal arc therapy for multiple brain metastases

Chen-Jun Jiang
Yick-Wing Ho
Harry Chi-Yuen Cheng
ResearchOpen Access17 Mar 2025
Scientific Reports

Volume: 15, P: 1-14
Observation of electroweak production of two jets and a Z-boson pair

The ATLAS Collaboration reports the observation of the electroweak production of two jets and a Z-boson pair. This process is related to vector-boson scattering and allows the nature of electroweak symmetry breaking to be probed.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access09 Feb 2023
Nature Physics

Volume: 19, P: 237-253
Microbiota-derived tryptophan catabolites mediate the chemopreventive effects of statins on colorectal cancer

Statins have anti-cancer effects that are modulated by the gut commensal Lactobacillus reuteri and the tryptophan metabolite, indole-3-lactic acid, in mice and humans.

Ji-Xuan Han
Zhi-Hang Tao
Jing-Yuan Fang
Research17 Apr 2023
Nature Microbiology

Volume: 8, P: 919-933
Accelerated pyro-catalytic hydrogen production enabled by plasmonic local heating of Au on pyroelectric BaTiO₃ nanoparticles

While pyrocatalysis offers a means to store energy in chemical bonds from temperature changes, most materials show low conversion efficiencies. Here, authors examine Au nanoparticles on BaTiO3 and demonstrate localized plasmonic heat sources to enhance pyrocatalytic H₂ evolution.

Huilin You
Siqi Li
Haitao Huang
ResearchOpen Access17 Oct 2022
Nature Communications

Volume: 13, P: 1-9
Physiological clearance of amyloid-beta by the kidney and its therapeutic potential for Alzheimer’s disease

Ding-Yuan Tian
Yuan Cheng
Yan-Jiang Wang
Research08 Apr 2021
Molecular Psychiatry

Volume: 26, P: 6074-6082
Impact of carbon monoxide poisoning on the risk of breast cancer

Chien-Cheng Huang
Chung-Han Ho
How-Ran Guo
ResearchOpen Access24 Nov 2020
Scientific Reports

Volume: 10, P: 1-8
Systematic identification of genes with a cancer-testis expression pattern in 19 cancer types

Genes normally expressed in the testis but aberrantly expressed in cancer are termed cancer testis antigens. In this study, the authors catalogue the expression of these genes in 19 different cancer types and correlate expression with some somatically mutated oncogenes.

Cheng Wang
Yayun Gu
Zhibin Hu
ResearchOpen Access27 Jan 2016
Nature Communications

Volume: 7, P: 1-12
The growth of the central region by acquisition of counterrotating gas in star-forming galaxies

Counter-rotating gases demonstrate external gas acquisition in galaxies, but their presence in blue, star-forming galaxies has not been studied systematically. Here, the authors analyse the MaNGA survey data to find a fraction of counter-rotators among blue galaxies whose central regions show ongoing growth.

Yan-Mei Chen
Yong Shi
Ren-Bin Yan
ResearchOpen Access19 Oct 2016
Nature Communications

Volume: 7, P: 1-9
Birefringence-like spin transport via linearly polarized antiferromagnetic magnons

Easy-plane antiferromagnet materials promise low-energy control of ultrafast magnetic dynamics in future spintronics applications, but host magnons with vanishing angular momentum, which makes spin transport via magnons unlikely. Through interference of two linearly polarized propagating magnons, spin transport over micrometre distances is yet possible.

Jiahao Han
Pengxiang Zhang
Luqiao Liu
Research01 Jun 2020
Nature Nanotechnology

Volume: 15, P: 563-568
Current-induced Néel order switching facilitated by magnetic phase transition

Electrical manipulation of antiferromagnetic order is crucial for future memory devices, but existing switching schemes require a large current density. Here, the authors achieve record low current density switching in FeRh by taking advantage of its antiferromagnetic to ferromagnetic phase transition.

Hao Wu
Hantao Zhang
Kang L. Wang
ResearchOpen Access28 Mar 2022
Nature Communications

Volume: 13, P: 1-7
LKB1 drives stasis and C/EBP-mediated reprogramming to an alveolar type II fate in lung cancer

LKB1 tumour suppressor gene is frequently mutated in lung adenocarcinoma. Here the authors show that in genetically engineered mouse models of lung cancer Lkb1 restoration induces growth arrest and drives neoplastic cells toward a more differentiated and less proliferative alveolar type II cell-like state via C/EBP-mediated reprogramming.

Christopher W. Murray
Jennifer J. Brady
Monte M. Winslow
ResearchOpen Access28 Feb 2022
Nature Communications

Volume: 13, P: 1-19
Deterministic switching of a perpendicularly polarized magnet using unconventional spin–orbit torques in WTe₂

The authors show that an out-of-plane antidamping spin–orbit torque can produce a sizeable change in the switching dynamics of a magnetic layer with perpendicular anisotropy.

I-Hsuan Kao
Ryan Muzzio
Simranjeet Singh
Research16 Jun 2022
Nature Materials

Volume: 21, P: 1029-1034
Coupling aqueous zinc batteries and perovskite solar cells for simultaneous energy harvest, conversion and storage

Accumulation of intermittent solar energy using secondary batteries is an appealing solution for future power sources. Here, the authors propose a device comprising of perovskite solar cells and aqueous zinc metal batteries connected via the sandwich joint electrode method.

Peng Chen
Tian-Tian Li
Xue-Ping Gao
ResearchOpen Access10 Jan 2022
Nature Communications

Volume: 13, P: 1-9
Mapping global lake dynamics reveals the emerging roles of small lakes

Lakes are essential components of the hydrological and biogeochemical cycles. Here, Pi et al develop a global lake dataset called GLAKES via high-resolution satellite images and deep learning to examine global lake changes over four decades.

Xuehui Pi
Qiuqi Luo
Brett A. Bryan
ResearchOpen Access01 Oct 2022
Nature Communications

Volume: 13, P: 1-12
Stability-limiting heterointerfaces of perovskite photovoltaics

Surface treatments for the passivation of defects in perovskite solar cells have a detrimental side effect that limits the maximum stability improvement.

Shaun Tan
Tianyi Huang
Yang Yang
Research15 Mar 2022
Nature

Volume: 605, P: 268-273
Test of the universality of τ and μ lepton couplings in W-boson decays with the ATLAS detector

The ATLAS Collaboration reports a measurement of the ratio of the decay rates of W bosons to τ leptons and muons, in agreement with universal lepton couplings as postulated in the standard model of particle physics.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access05 Jul 2021
Nature Physics

Volume: 17, P: 813-818
Search for charged-lepton-flavour violation in Z-boson decays with the ATLAS detector

The ATLAS experiment at the Large Hadron Collider reports a search for charged-lepton-flavour violation in decays of Z bosons into a τ lepton and an electron or muon of opposite charge.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access01 Jul 2021
Nature Physics

Volume: 17, P: 819-825
Antiferromagnetic Spin Wave Field-Effect Transistor

Ran Cheng
Matthew W. Daniels
Di Xiao
ResearchOpen Access06 Apr 2016
Scientific Reports

Volume: 6, P: 1-6
Causal effects of gut microbiota on the risk of erectile dysfunction: a Mendelian randomization study

Ran Xu
Shuo Liu
Xin-Jun Wang
Research25 Jan 2024
International Journal of Impotence Research

Volume: 36, P: 858-863
Few-shot concealed object detection in sub-THz security images using improved pseudo-annotations

Ran Cheng
Stepan Lucyszyn
ResearchOpen Access07 Feb 2024
Scientific Reports

Volume: 14, P: 1-9
Alcohol consumption and risks of more than 200 diseases in Chinese men

Observational analyses from the China Kadoorie Biobank found that alcohol consumption was associated with higher risks of 61 diseases in Chinese men, with most of these associations confirmed by genetic analyses.

Pek Kei Im
Neil Wright
Xiaoyi Zhang
ResearchOpen Access08 Jun 2023
Nature Medicine

Volume: 29, P: 1476-1486
Multi-dimensional intelligent reorganization and utilization of knowledge in ‘Biographies of Chinese Thinkers’

Jiangfeng Liu
Zhiyuan Liu
Lei Pei
ResearchOpen Access05 May 2025
npj Heritage Science

Volume: 13, P: 1-20
Pumped storage hydropower operation for supporting clean energy systems

Pumped storage hydropower stores energy and provides services for the electrical grid. This Review discusses the types, applications and broader effects of this form of grid-scale energy storage.

Weijia Yang
Zhigao Zhao
Yongguang Cheng
Reviews27 May 2025
Nature Reviews Clean Technology

Volume: 1, P: 454-473
The activity and immune dynamics of PD-1 inhibition on high-risk pulmonary ground glass opacity lesions: insights from a single-arm, phase II trial

Bo Cheng
Caichen Li
Wenhua Liang
ResearchOpen Access19 Apr 2024
Signal Transduction and Targeted Therapy

Volume: 9, P: 1-13
CD300E⁺ macrophages facilitate liver regeneration after splenectomy in decompensated cirrhotic patients

Tao Yang
Yuan Zhang
Jikai Yin
ResearchOpen Access01 Jan 2025
Experimental & Molecular Medicine

Volume: 57, P: 72-85
Observation of reflectionless absorption due to spatial Kramers–Kronig profile

Reflectionless absorption independent of the angle of incidence usually requires the introduction of gain media into the system. Here, Ye et al. implement a recent theoretical proposal to achieve this with a spatially varying permittivity, showing that this approach is experimentally feasible.

Dexin Ye
Cheng Cao
Lixin Ran
ResearchOpen Access03 Jul 2017
Nature Communications

Volume: 8, P: 1-10
Genetic landscape of esophageal squamous cell carcinoma

Jie He and colleagues report exome sequencing of 113 tumor-normal pairs of esophageal squamous cell carcinoma. They highlight mutations in genes involved in cell cycle and apoptosis regulation, histone modifier genes and genes encoding members of the Hippo and Notch pathways.

Yi-Bo Gao
Zhao-Li Chen
Jie He
Research24 Aug 2014
Nature Genetics

Volume: 46, P: 1097-1102
Daidzein alleviates skin fibrosis by suppressing TGF-β1 signaling pathway via targeting PKM2

Xiaowei Guo
Wenqi Li
Cheng Yang
ResearchOpen Access13 Mar 2025
Scientific Reports

Volume: 15, P: 1-16
A detailed map of Higgs boson interactions by the ATLAS experiment ten years after the discovery

Ten years after the discovery of the Higgs boson, the ATLAS experiment at CERN probes its kinematic properties with a significantly larger dataset from 2015–2018 and provides further insights on its interaction with other known particles.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access04 Jul 2022
Nature

Volume: 607, P: 52-59
Late Miocene Tarim desert wetting linked with eccentricity minimum and East Asian monsoon weakening

The late Miocene Tarim desert experienced periodic wetting and greening in eccentricity minimum and East Asian summer monsoon weakening

Junsheng Nie
Weihang Wang
Wenjiao Xiao
ResearchOpen Access08 Jul 2022
Nature Communications

Volume: 13, P: 1-8
Predictive value of system immune-inflammation index for the severity of coronary stenosis in patients with coronary heart disease and diabetes mellitus

Haiming Wang
Zhihang Huang
Yiming Mu
ResearchOpen Access28 Dec 2024
Scientific Reports

Volume: 14, P: 1-13
Intravoxel incoherent motion diffusion-weighted imaging to differentiate hepatocellular carcinoma from intrahepatic cholangiocarcinoma

Juan Peng
Jing Zheng
Lin Yang
ResearchOpen Access07 May 2020
Scientific Reports

Volume: 10, P: 1-7
Plasma phenylalanine and glutamine concentrations correlate with subsequent hepatocellular carcinoma occurrence in liver cirrhosis patients: an exploratory study

Kung-Hao Liang
Mei-Ling Cheng
Chau-Ting Yeh
ResearchOpen Access02 Jul 2020
Scientific Reports

Volume: 10, P: 1-7
Gastrin releasing peptide receptor targeted nano-graphene oxide for near-infrared fluorescence imaging of oral squamous cell carcinoma

Ran Li
Ruifang Gao
Lixin Ma
ResearchOpen Access10 Jul 2020
Scientific Reports

Volume: 10, P: 1-12
One-Pot Radiosynthesis and Biological Evaluation of a Caspase-3 Selective 5-[^123,125I]iodo-1,2,3-triazole derived Isatin SPECT Tracer

Matthias Glaser
Vineeth Rajkumar
Erik Årstad
ResearchOpen Access17 Dec 2019
Scientific Reports

Volume: 9, P: 1-8
Geriatric influenza death (GID) score: a new tool for predicting mortality in older people with influenza in the emergency department

Jui-Yuan Chung
Chien-Chin Hsu
Chien-Cheng Huang
ResearchOpen Access18 Jun 2018
Scientific Reports

Volume: 8, P: 1-8
Icy heart could be key to Pluto’s strange geology

NASA’s New Horizons mission plumbs complex interplay between the dwarf planet's surface and its sky.

Alexandra Witze
News21 Oct 2016
Nature

Volume: 538, P: 439
Effects of ferulic acid on diabetic nephropathy in a rat model of type 2 diabetes

Ran Choi
Bo Hwan Kim
Choon Hee Chung
ResearchOpen Access06 Oct 2011
Experimental & Molecular Medicine

Volume: 43, P: 676-683

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