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Pediatric Research (1)
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Advanced filters: Author: Ricardo Seminario Clear advanced filters

Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design

Here the authors demonstrate that the SARS-CoV-2 main protease (Mpro) is subject to redox regulation in vitro, reversibly switching between the enzymatically active dimer and the functionally dormant monomer through redox modifications of cysteine residues.

Lisa-Marie Funk
Gereon Poschmann
Kai Tittmann
ResearchOpen Access09 Jan 2024
Nature Communications

Volume: 15, P: 1-18
High incidence of stroke and mortality in pediatric critical care patients with COVID-19 in Peru

Alvaro Coronado Munoz
Jaime Tasayco
Jesús Domínguez
Research03 May 2021
Pediatric Research

Volume: 91, P: 1730-1734

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Multiple redox switches of the SARS-CoV-2 main protease in vitro provide opportunities for drug design

High incidence of stroke and mortality in pediatric critical care patients with COVID-19 in Peru

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