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Showing 1–50 of 116 results

Advanced filters: Author: Richard E. Rothman Clear advanced filters

An AI-driven clinical care pathway to reduce 30-day readmission for chronic obstructive pulmonary disease (COPD) patients

Lin Wang
Guihua Li
Stephen T. C. Wong
ResearchOpen Access30 Nov 2022
Scientific Reports

Volume: 12, P: 1-9
A consensus immune dysregulation framework for sepsis and critical illnesses

In an integrated analysis of transcriptomic data from the SUBSPACE consortium and public datasets of patients with sepsis, acute respiratory distress syndrome, trauma and burns, dysregulation within four consensus molecular clusters related to myeloid and lymphoid cells is associated with mortality and illness severity.

Andrew R. Moore
Hong Zheng
Purvesh Khatri
ResearchOpen Access30 Sept 2025
Nature Medicine

P: 1-13
Clinical validation of an AI-based blood testing device for diagnosis and prognosis of acute infection and sepsis

In a prospective study enrolling 1,222 patients from 22 emergency departments, a device using a machine-learning-based signature of blood mRNAs demonstrated clinically acceptable performance to diagnose bacterial and viral infections and to predict the all-cause need for critical care interventions within 7 days, with benchmark to established biomarkers and risk scores.

Oliver Liesenfeld
Sanjay Arora
Nathan I. Shapiro
ResearchOpen Access30 Sept 2025
Nature Medicine

P: 1-11
Identification of two copies of the gene for the elongation factor EF–Tu in E. Coli

S. Richard Jaskunas
Lasse Lindahl
Richard R. Burgess
Research09 Oct 1975
Nature

Volume: 257, P: 458-462
Receptor and protein kinase C-mediated regulation of ARF binding to the Golgi complex

Maria Antonietta De Matteis
Giovanna Santini
Alberto Luini
Research26 Aug 1993
Nature

Volume: 364, P: 818-821
Brefeldin A inhibits Golgi membrane-catalysed exchange of guanine nucleotide onto ARF protein

Julie G. Donaldson
Dario Finazzi
Richard D. Klausner
Research26 Nov 1992
Nature

Volume: 360, P: 350-352
Requirement for the replication protein SSB in human DMA excision repair

Dawn Coverley
Mark K. Kenny
Richard D. Wood
Research07 Feb 1991
Nature

Volume: 349, P: 538-541
Solar luminosity variations in solar cycle 21

Richard C. Willson
H. S. Hudson
Research28 Apr 1988
Nature

Volume: 332, P: 810-812
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene

Kazuya Shimoda
Jan van Deursent
J. N. Ihle
Research18 Apr 1996
Nature

Volume: 380, P: 630-633
Hrs-2 is an ATPase implicated in calcium-regulated secretion

Andrew J. Bean
Roland Seifert
Richard H. Scheller
Research27 Feb 1997
Nature

Volume: 385, P: 826-829
Voltage-dependent translocation of the asialoglycoprotein receptor across lipid membranes

Robert Blumenthal
Richard D. Klausner
John N. Weinstein
Research27 Nov 1980
Nature

Volume: 288, P: 333-338
Accurate, noninvasive diagnosis of human brain tumors by using proton magnetic resonance spectroscopy

Mark C. Preul
Zografos Caramanos
Douglas L. Arnold
Research01 Mar 1996
Nature Medicine

Volume: 2, P: 323-325
In search of the molecular mechanism of intracellular membrane fusion and neurotransmitter release

Richard H Scheller
Comments & Opinion07 Oct 2013
Nature Medicine

Volume: 19, P: 1232-1235
Targeted disruption of the tyrosine hydroxylase gene reveals that catecholamines are required for mouse fetal development

Qun-Yong Zhou
Carol J. Quaife
Richard D. Palmiter
Research13 Apr 1995
Nature

Volume: 374, P: 640-643
Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP

Richard C. Yu
Phyllis I. Hanson
Axel T. Brünger
Research01 Sept 1998
Nature Structural Biology

Volume: 5, P: 803-811
CFTR and outward rectifying chloride channels are distinct proteins with a regulatory relationship

Sherif E. Gabriel
Lane L. Clarke
M. Jackson Stutts
Research20 May 1993
Nature

Volume: 363, P: 263-266
Noradrenaline is essential for mouse fetal development

Steven A. Thomas
Alvin M. Matsumoto
Richard D. Palmiter
Research13 Apr 1995
Nature

Volume: 374, P: 643-646
The feasibility of a primary care model for the management of COPD

Marianne A. Meulepas
Johanna E. Jacobs
Richard P.T.M. Grol
Research01 Dec 2006
Primary Care Respiratory Journal

Volume: 15, P: 337-341
The specifics of membrane fusion

Tiny, membrane-clad vesicles transport substances between intracellular compartments. But how does the cell ensure that the vesicle gets its cargo to the right place? SNARE proteins are involved in the recognition process, and new experiments tackle the question of this specificity.

Suzie J. Scales
Jason B. Bock
Richard H. Scheller
News & Views14 Sept 2000
Nature

Volume: 407, P: 144-146
A Drosophila NSF mutant

Leo Pallanck
Richard W. Ordway
Barry Ganetzky
Research06 Jul 1995
Nature

Volume: 376, P: 25
New data on excisions of Mu from E. coli MCS2 cast doubt on directed mutation hypothesis

John E. Mittler
Richard E. Lenski
Research08 Mar 1990
Nature

Volume: 344, P: 173-175
Apolipoprotein B intermediates

RICHARD PEASE
GEORGINA HARRISON
JAMES SCOTT
Research12 Mar 1992
Nature

Volume: 356, P: 115-116
Mitochondrial heat-shock protein hsp60 is essential for assembly of proteins imported into yeast mitochondria

Ming Y. Cheng
F.-Ulrich Hartl
Arthur L. Horwich
Research16 Feb 1989
Nature

Volume: 337, P: 620-625
Membrane protein association by potential intrarnembrane charge pairs

Pierre Cosson
Scott P. Lankford
Richard D. Klausner
Research30 May 1991
Nature

Volume: 351, P: 414-416
Temporal trends of a cellular host response test for sepsis and a comparison with selected biomarkers of inflammation and infection

Matthew S. Berlinger
Matt Sorrells
Richard Rothman
ResearchOpen Access20 Aug 2025
Scientific Reports

Volume: 15, P: 1-11
Evidence for a Role of Transporter-Mediated Currents in the Depletion of Brain Serotonin Induced by Serotonin Transporter Substrates

Michael H Baumann
Simon Bulling
Harald H Sitte
ResearchOpen Access28 Nov 2013
Neuropsychopharmacology

Volume: 39, P: 1355-1365
High-Curie-temperature ferromagnetism in self-organized Ge_1−xMn_x nanocolumns

Matthieu Jamet
André Barski
Serge Tatarenko
Research09 Jul 2006
Nature Materials

Volume: 5, P: 653-659
Snowball Earth prevention by dissolved organic carbon remineralization

A model study of the coupled evolution of the carbon cycle and the climate system during the Neoproterozoic is presented. This finds that more oxygen is taken up by a cooling ocean, which converts organic into inorganic carbon more efficiently, creating a negative feedback loop that stabilises low carbon dioxide levels and prevents total glaciation.

W. Richard Peltier
Yonggang Liu
John W. Crowley
Research06 Dec 2007
Nature

Volume: 450, P: 813-818
Molecular cloning of the microtubule-associated mechanochemical enzyme dynamin reveals homology with a new family of GTP-binding proteins

Robert A. Obar
Christine A. Collins
Richard B. Vallee
Research20 Sept 1990
Nature

Volume: 347, P: 256-261
Sex differences in the functional organization of the brain for language

Bennett A. Shaywitz
Sally E. Shaywltz
John C. Gore
Research16 Feb 1995
Nature

Volume: 373, P: 607-609
Dynamin is a GTPase stimulated to high levels of activity by microtubules

Howard S. Shpetner
Richard B. Vallee
Research20 Feb 1992
Nature

Volume: 355, P: 733-735
Arrest of spermatogenesis and defective breast development in mice lacking A-myb

Antonio Toscani
Richard V. Mettus
E. Premkumar Reddy
Research17 Apr 1997
Nature

Volume: 386, P: 713-717
Genome-wide association study of lung adenocarcinoma in East Asia and comparison with a European population

Genome-wide association studies (GWAS) have improved our understanding of the genetic basis of lung adenocarcinoma but known susceptibility variants explain only a small fraction of the familial risk. Here, the authors perform a two-stage GWAS and report 12 novel genetic loci associated with lung adenocarcinoma in East Asians.

Jianxin Shi
Kouya Shiraishi
Qing Lan
ResearchOpen Access26 May 2023
Nature Communications

Volume: 14, P: 1-17
Mutation of a type II keratin gene (K6a) in pachyonychia congenita

Paul E. Bowden
Joanne L. Haley
Richard J. Turner
Research01 Jul 1995
Nature Genetics

Volume: 10, P: 363-365
Quantitative assessment of blood flow, blood volume and blood oxygenation effects in functional magnetic resonance imaging

Peter C.M. van Zijl
Scott M. Eleff
Risto A. Kauppinen
Research01 Feb 1998
Nature Medicine

Volume: 4, P: 159-167
ATP-dependent inositide phosphorylation required for Ca²⁺-activated secretion

Jesse C. Hay
Phillip L Fisette
Thomas F. J. Martin
Research09 Mar 1995
Nature

Volume: 374, P: 173-177
Activation of specific RXR heterodimers by an antagonist of RXR homodimers

Deepak S. Lala
Ranjan Mukherjee
Richard A. Heyman
Research03 Oct 1996
Nature

Volume: 383, P: 450-453
Assessment of polygenic architecture and risk prediction based on common variants across fourteen cancers

In cancer many gene variants may contribute to disease etiology, but the impact of a given gene variant may have varied effect size. Here, the authors analyse summary statistics of genome-wide association studies from fourteen cancers, and show the utility of polygenic risk scores may vary depending on cancer type.

Yan Dora Zhang
Amber N. Hurson
Montserrat Garcia-Closas
ResearchOpen Access03 Jul 2020
Nature Communications

Volume: 11, P: 1-13
Regulation of NMDA receptor phosphorylation by alternative splicing of the C-terminal domain

Whittemore G. Tingley
Katherine W. Roche
Richard L. Huganir
Research01 Jul 1993
Nature

Volume: 364, P: 70-73
Genome-wide association study identifies multiple risk loci for renal cell carcinoma

Risk for renal cell carcinoma (RCC) is higher when there are first-degree family members with the disease. Here, Scelo and colleagues perform a genome-wide association meta-analysis and new genome-wide scan to identify seven new loci with significant RCC association.

Ghislaine Scelo
Mark P. Purdue
Stephen J. Chanock
ResearchOpen Access09 Jun 2017
Nature Communications

Volume: 8, P: 1-9
Integration of motion and stereopsis in middle temporal cortical area of macaques

David C. Bradley
Ning Qian
Richard A. Andersen
Research16 Feb 1995
Nature

Volume: 373, P: 609-611
Extremely strong carbon monoxide emission from the Cloverleaf quasar at a redshift of 2.5

Richard Barvainis
Linda Tacconi
Paul Coleman
Research13 Oct 1994
Nature

Volume: 371, P: 586-588
Multiple forms of dynamin are encoded by shibire, a Drosophila gene involved in endocytosis

Maio S. Chen
Robert A. Obar
Richard B. Vallee
Research13 Jun 1991
Nature

Volume: 351, P: 583-586
Crisscross regulation of cell-type-specific gene expression during development in B. subtilis

Richard Losick
Patrick Stragier
Reviews13 Feb 1992
Nature

Volume: 355, P: 601-604
Multi-ancestry genome-wide association study of kidney cancer identifies 63 susceptibility regions

A multi-ancestry genome-wide association meta-analysis of kidney cancer identifies 63 regions associated with disease susceptibility including one locus that was associated with increased risk in individuals with African ancestry.

Mark P. Purdue
Diptavo Dutta
Stephen J. Chanock
Research26 Apr 2024
Nature Genetics

Volume: 56, P: 809-818
Genome-wide association analysis implicates dysregulation of immunity genes in chronic lymphocytic leukaemia

Chronic lymphocytic leukaemia has a hereditary component, much of which remains to be identified. Here, the authors perform a genome-wide association study and find new risk loci for the disease, which are associated with genes involved in immune function.

Philip J. Law
Sonja I. Berndt
Susan Slager
ResearchOpen Access06 Feb 2017
Nature Communications

Volume: 8, P: 1-12
Powerful Cocaine-Like Actions of 3,4-Methylenedioxypyrovalerone (MDPV), a Principal Constituent of Psychoactive ‘Bath Salts’ Products

Michael H Baumann
John S Partilla
Charles W Schindler
Research17 Oct 2012
Neuropsychopharmacology

Volume: 38, P: 552-562
Effect of Acetylsalicylic Acid on Fatty Acid ω-Hydroxylation in Rat Liver

Richard Okita
Research01 Dec 1986
Pediatric Research

Volume: 20, P: 1221-1224
1592 NEURODEVELOPMENTAL FOLLOW-UP OF VLBW NEONATES: EFFECTS OF GMH/IVH

Laura R Ment
David T Scott
Joseph B Warshaw
Research01 Apr 1981
Pediatric Research

Volume: 15, P: 708
A fusion of new ideas

Jason B. Bock
Richard H. Scheller
News & Views08 May 1997
Nature

Volume: 387, P: 133-134

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