Nature Search

Upregulated hepatic lipogenesis from dietary sugars in response to low palmitate feeding supplies brain palmitate

The origin of brain palmitic acid (PAM) has been debated. Here, by using natural abundance carbon isotope ratios and RNA sequencing the authors show that the majority of brain PAM is maintained by hepatic PAM synthesis from dietary sugars during development and is upregulated in mice fed low PAM.

Mackenzie E. Smith
Chuck T. Chen
Richard P. Bazinet
ResearchOpen Access17 Jan 2024
Nature Communications

Volume: 15, P: 1-15
Membrane protein association by potential intrarnembrane charge pairs

Pierre Cosson
Scott P. Lankford
Richard D. Klausner
Research30 May 1991
Nature

Volume: 351, P: 414-416
Polyunsaturated fatty acids and their metabolites in brain function and disease

Polyunsaturated fatty acids (PUFAs) and their biologically active derivatives regulate many processes in the brain, including neurotransmission, cell survival and inflammation. Bazinet and Layé review PUFA metabolism and functions in the brain and discuss the potential for PUFA supplementation in psychiatric and neurodegenerative disorders.

Richard P. Bazinet
Sophie Layé
Reviews12 Nov 2014
Nature Reviews Neuroscience

Volume: 15, P: 771-785
A simulated annealing algorithm for randomizing weighted networks

This study proposes an algorithm for generating randomized networks that preserve the weighted degree sequence. The procedure outperforms standard rewiring algorithms and extends to multiple network types, including directed and signed networks.

Filip Milisav
Vincent Bazinet
Bratislav Misic
ResearchOpen Access10 Dec 2024
Nature Computational Science

Volume: 5, P: 48-64
Differentiating the pathologies of cerebral malaria by postmortem parasite counts

Terrie E Taylor
Wenjiang J Fu
Malcolm E Molyneux
Research25 Jan 2004
Nature Medicine

Volume: 10, P: 143-145
Contributions of network structure, chemoarchitecture and diagnostic categories to transitions between cognitive topographies

An analysis of neuroimaging data across mental health, neurodegenerative, psychiatric and neurodevelopmental diagnostic categories highlights how brain network organization and chemoarchitecture interact to shape cognitive topographies.

Andrea I. Luppi
S. Parker Singleton
Bratislav Misic
ResearchOpen Access05 Aug 2024
Nature Biomedical Engineering

Volume: 8, P: 1142-1161
Pharmaceutical Capsules as a Coating System for Artificial Seeds

Jean-Marc Dupuis
Catherine Roffat
Francis Molle
Research01 Apr 1994
Bio/Technology

Volume: 12, P: 385-389
Metabolomic profiling of a cholesterol lowering plant-based diet from two randomized controlled feeding trials

Andrea J. Glenn
Anne-Julie Tessier
John L. Sievenpiper
Research22 Apr 2025
European Journal of Clinical Nutrition

Volume: 79, P: 863-875
Fatty acid dysregulation in the anterior cingulate cortex of depressed suicides with a history of child abuse

Kelly Perlman
Raphaël Chouinard-Watkins
Naguib Mechawar
ResearchOpen Access18 Oct 2021
Translational Psychiatry

Volume: 11, P: 1-8
Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB

Laura M. Best
Belinda Williams
Isabelle Boileau
Research07 Jan 2020
Neuropsychopharmacology

Volume: 45, P: 1289-1296
Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain

Chuck T. Chen
Alex P. Kitson
Richard P. Bazinet
ResearchOpen Access29 Oct 2015
Scientific Reports

Volume: 5, P: 1-12
Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

Hansen et al. compile and share an atlas of neurotransmitter receptor/transporter densities in the human cortex and show that receptor achitecture reflects brain structure, function, dynamics, cognitive specialization and disease vulnerability.

Justine Y. Hansen
Golia Shafiei
Bratislav Misic
ResearchOpen Access27 Oct 2022
Nature Neuroscience

Volume: 25, P: 1569-1581
Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction

Rehnuma Islam
Marc-Olivier Trépanier
Amy J. Ramsey
ResearchOpen Access22 Mar 2017
npj Schizophrenia

Volume: 3, P: 1-8
Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission

Marie Hennebelle
Zhichao Zhang
Ameer Y. Taha
ResearchOpen Access28 Jun 2017
Scientific Reports

Volume: 7, P: 1-14
Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

Harsh R. Desai
Tharini Sivasubramaniyam
Minna Woo
ResearchOpen Access09 Aug 2017
Scientific Reports

Volume: 7, P: 1-15
Time-resolved structure-function coupling in brain networks

Temporal unwrapping analysis of diffusion weighted MRI connectivity and functional MRI scans reveals that the coupling between structure and function in the human brain is regionally heterogeneous and provides a framework to evaluate these relationships from a dynamic perspective.

Zhen-Qi Liu
Bertha Vázquez-Rodríguez
Bratislav Misic
ResearchOpen Access02 Jun 2022
Communications Biology

Volume: 5, P: 1-10
Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review

M O Trépanier
K E Hopperton
R P Bazinet
ReviewsOpen Access07 Jun 2016
Molecular Psychiatry

Volume: 21, P: 1009-1026
Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review

K E Hopperton
D Mohammad
R P Bazinet
ReviewsOpen Access12 Dec 2017
Molecular Psychiatry

Volume: 23, P: 177-198
Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?

J S Rao
H-J Lee
R P Bazinet
Reviews18 Mar 2008
Molecular Psychiatry

Volume: 13, P: 585-596

Search

Upregulated hepatic lipogenesis from dietary sugars in response to low palmitate feeding supplies brain palmitate

Membrane protein association by potential intrarnembrane charge pairs

Polyunsaturated fatty acids and their metabolites in brain function and disease

A simulated annealing algorithm for randomizing weighted networks

Differentiating the pathologies of cerebral malaria by postmortem parasite counts

Contributions of network structure, chemoarchitecture and diagnostic categories to transitions between cognitive topographies

Pharmaceutical Capsules as a Coating System for Artificial Seeds

Metabolomic profiling of a cholesterol lowering plant-based diet from two randomized controlled feeding trials

Fatty acid dysregulation in the anterior cingulate cortex of depressed suicides with a history of child abuse

Lower brain fatty acid amide hydrolase in treatment-seeking patients with alcohol use disorder: a positron emission tomography study with [C-11]CURB

Plasma non-esterified docosahexaenoic acid is the major pool supplying the brain

Mapping neurotransmitter systems to the structural and functional organization of the human neocortex

Vulnerability to omega-3 deprivation in a mouse model of NMDA receptor hypofunction

Linoleic acid participates in the response to ischemic brain injury through oxidized metabolites that regulate neurotransmission

Macrophage JAK2 deficiency protects against high-fat diet-induced inflammation

Time-resolved structure-function coupling in brain networks

Postmortem evidence of cerebral inflammation in schizophrenia: a systematic review

Markers of microglia in post-mortem brain samples from patients with Alzheimer’s disease: a systematic review

Mode of action of mood stabilizers: is the arachidonic acid cascade a common target?

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