Barrington's nucleus, the pontine micturition centre, is central to a circuit involved in the coordination of pelvic visceral activity with appropriate elimination behaviors. In this Review, the authors discuss the neuroanatomy of Barrington's nucleus and its projections, and the role of this nucleus in urological disorders. They also discuss a putative role for corticotropin-releasing factor as a potential mediator of these effects.
- Rita J. Valentino
- Susan K. Wood
- Stephen A. Zderic
