Nature Search

Association of Sos Ras exchange protein with Grb2 is implicated in tyrosine kinase signal transduction and transformation

Sean E. Egan
Barton W. Giddings
Robert A. Weinberg
Research06 May 1993
Nature

Volume: 363, P: 45-51
The Grb2 binding domain of mSos1 is not required for downstream signal transduction

Wei Wang
Elizabeth M.C. Fisher
Sean E. Egan
Research01 Jul 1995
Nature Genetics

Volume: 10, P: 294-300
A mutation that impairs the ability of lipoprotein receptors to localise in coated pits on the cell surface of human fibroblasts

Richard G. W. Anderson
Joseph L. Goldstein
Michael S. Brown
Research01 Dec 1977
Nature

Volume: 270, P: 695-699
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression

Whole-genome analysis of paired follicular lymphoma and double-hit lymphoma shows that lymphoma progression is accompanied by enhanced somatic mutations targeting super-enhancer-embedded promoters.

Rebecca J. Leeman-Neill
Dong Song
Uttiya Basu
ResearchOpen Access04 Dec 2023
Nature Genetics

Volume: 55, P: 2160-2174
Origin of diamonds in old enriched mantle

S. H. Richardson
J. J. Gurney
J. W. Harris
Research19 Jul 1984
Nature

Volume: 310, P: 198-202
Acid-dependent ligand dissociation and recycling of LDL receptor mediated by growth factor homology region

C. Geoffrey Davis
Joseph L. Goldstein
Michael S. Brown
Research01 Apr 1987
Nature

Volume: 326, P: 760-765
Loss of NF1 results in activation of the Ras signaling pathway and leads to aberrant growth in haematopoietic cells

Gideon Bollag
D. Wade Clapp
Kevin Shannon
Research01 Feb 1996
Nature Genetics

Volume: 12, P: 144-148
A systematic review and meta-analysis of heat exposure impacts on maternal, fetal and neonatal health

A systematic review and meta-analysis of studies covering 66 countries reported wide-ranging maternal, fetal and neonatal health harms associated with heat exposure, including increased risks of preterm birth, stillbirths, obstetric complications, congenital anomalies and gestational diabetes.

Darshnika P. Lakhoo
Nicholas Brink
Nicholas Brink
ResearchOpen Access05 Nov 2024
Nature Medicine

Volume: 31, P: 684-694
Mapping local patterns of childhood overweight and wasting in low- and middle-income countries between 2000 and 2017

Fine-scale geospatial mapping of overweight and wasting (two components of the double burden of malnutrition) in 105 LMICs shows that overweight has increased from 5.2% in 2000 to 6.0% in children under 5 in 2017. Although overall wasting decreased over the same period, most countries are not on track to meet the World Health Organization’s Global Nutrition Target of <5% in over half of LMICs by 2025.

Damaris K. Kinyoki
Jennifer M. Ross
Simon I. Hay
ResearchOpen Access20 Apr 2020
Nature Medicine

Volume: 26, P: 750-759
Discovery and physical properties of Dactyl, a satellite of asteroid 243 Ida

C. R. Chapman
J. Veverka
T. Denk
Research27 Apr 1995
Nature

Volume: 374, P: 783-785
WNK1-dependent water influx is required for CD4⁺ T cell activation and T cell-dependent antibody responses

T cell antigen receptor stimulation by the ligand antigen triggers multiple downstream pathways that affect CD4 + T cell function. Here authors show that activation of the downstream WNK1 kinase causes water entry into the cells, which is essential for CD4⁺ T cell proliferation.

Joshua Biggs O’May
Lesley Vanes
Victor L. J. Tybulewicz
ResearchOpen Access21 Feb 2025
Nature Communications

Volume: 16, P: 1-17
Experience-dependent dopamine modulation of male aggression

Dopaminergic neurons in the ventral tegmental area have a role in modulating aggression in adult male mice, and this effect of dopamine depends strongly on fighting experience.

Bing Dai
Bingqin Zheng
Dayu Lin
Research22 Jan 2025
Nature

Volume: 639, P: 430-437
Google Scholar pioneer on search engine’s future

As the search engine approaches its 10th birthday, Nature speaks to the co-creator of Google Scholar.

Richard Van Noorden
News07 Nov 2014
Nature
Association between chronic fatigue syndrome/myalgic encephalomyelitis and cardiovascular disease

Mawulorm K. I. Denu
Ritika Revoori
Maame Araba E. Buadu
ResearchOpen Access17 Jan 2025
Scientific Reports

Volume: 15, P: 1-7
Shifts in receptors during submergence of an encephalitic arbovirus

Knockout studies using CRISPR–Cas9 identify PCDH10 as a selective host cellular receptor for western equine encephalitis virus.

Wanyu Li
Jessica A. Plante
Jonathan Abraham
ResearchOpen Access24 Jul 2024
Nature

Volume: 632, P: 614-621
The GenomeAsia 100K Project enables genetic discoveries across Asia

Using whole-genome sequencing data from 1,739 individuals, the GenomeAsia 100K Project catalogues genetic variation, population structure and disease associations to facilitate genetic studies in Asian populations and increase representation in genetics studies worldwide.

Jeffrey D. Wall
Eric W. Stawiski
Andrew S. Peterson
ResearchOpen Access04 Dec 2019
Nature

Volume: 576, P: 106-111
IL-21 induces IL-22 production in CD4+ T cells

The cytokine interleukin-22 maintains the integrity of the colonic epithelium during inflammation. Here, the authors show that IL-21 regulates the production of IL-22 in T cells and this mechanism plays a protective role in a mouse model of colitis.

Ada Yeste
Ivan D. Mascanfroni
Francisco J Quintana
Research06 May 2014
Nature Communications

Volume: 5, P: 1-13
Structural basis for VLDLR recognition by eastern equine encephalitis virus

Alphaviruses include several important human pathogens with outbreak potential. Here, the authors found that eastern equine encephalitis virus and Semliki Forest virus use distinct surfaces on their spike proteins to bind their shared receptor, VLDLR.

Pan Yang
Wanyu Li
Jonathan Abraham
ResearchOpen Access02 Aug 2024
Nature Communications

Volume: 15, P: 1-14
The dynamic landscape of transcription initiation in yeast mitochondria

Conformational dynamics during the early stage of transcription is crucial to understanding the regulation of transcription efficiency and fidelity. Here the authors, by single-molecule fluorescence resonance energy transfer approaches, examine the conformational dynamics of the two-component transcription system of yeast mitochondria with single-base resolution.

Byeong-Kwon Sohn
Urmimala Basu
Hajin Kim
ResearchOpen Access27 Aug 2020
Nature Communications

Volume: 11, P: 1-12
Selection Effects and the Nature of QSO Redshifts

K. G. KARLSSON
Correspondence01 Oct 1973
Nature Physical Science

Volume: 245, P: 68-70
Can Kimberlites be generated from an ordinary mantle?

J. D. Kramers
C. B. Smith
F. R. Boyd
Research07 May 1981
Nature

Volume: 291, P: 53-56
Precision targeting of autoantigen-specific B cells in muscle-specific tyrosine kinase myasthenia gravis with chimeric autoantibody receptor T cells

A muscle autoimmune disease is treated in mice with CAAR T cells.

Sangwook Oh
Xuming Mao
Aimee S. Payne
ResearchOpen Access19 Jan 2023
Nature Biotechnology

Volume: 41, P: 1229-1238
The cerebellum modulates thirst

Chopra and colleagues show that the hormone asprosin, independent of its effects on hypothalamic AgRP neurons, activates its cell surface receptor Ptprd on cerebellar Purkinje neurons to enhance thirst for maintenance of fluid homeostasis.

Ila Mishra
Bing Feng
Atul R. Chopra
Research10 Jul 2024
Nature Neuroscience

Volume: 27, P: 1745-1757
Chandrayaan-3 APXS elemental abundance measurements at lunar high latitude

In situ measurements of the elemental abundances in the lunar southern high-latitude regions show that the local terrain is fairly uniform and mostly composed of ferroan anorthosite, a product of lunar magma ocean crystallization.

Santosh V. Vadawale
N. P. S. Mithun
Amitabh
Research21 Aug 2024
Nature

Volume: 633, P: 327-331
Decreased serum retinol levels in women with cervical dysplasia

H Shimizu
C Nagata
S Hisamichi
Research01 Jun 1996
British Journal of Cancer

Volume: 73, P: 1600-1604
SARS-CoV-2-specific immune responses and clinical outcomes after COVID-19 vaccination in patients with immune-suppressive disease

Serological analysis and infection outcomes of participants in the multi-center, prospectively enrolled OCTAVE cohort, comprising 2,686 participants with immune-suppressive diseases who recieved two COVID-19 vaccines, reveals specific clinical phenotypes that might benefit from specific COVID-19 therapeutic strategies.

Eleanor Barnes
Carl S. Goodyear
Deborah Richardson
ResearchOpen Access06 Jul 2023
Nature Medicine

Volume: 29, P: 1760-1774
Coated pits, coated vesicles, and receptor-mediated endocytosis

Joseph L. Goldstein
Richard G. W. Anderson
Michael S. Brown
Reviews21 Jun 1979
Nature

Volume: 279, P: 679-685
Structures illustrate step-by-step mitochondrial transcription initiation

A cryogenic electron microscopy study presents structures characterizing the initiation of RNA synthesis by yeast mitochondrial RNA polymerase at single-nucleotide addition steps.

Quinten Goovaerts
Jiayu Shen
Kalyan Das
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 872-879
RIF1 integrates DNA repair and transcriptional requirements during the establishment of humoral immune responses

Here the authors reveal that in addition to promoting class switch recombination via inhibition of DNA end processing, RIF1 fine-tunes the kinetics of plasma cell differentiation, thus providing an additional layer of control in the establishment of humoral immunity.

Eleni Kabrani
Ali Rahjouei
Michela Di Virgilio
ResearchOpen Access17 Jan 2025
Nature Communications

Volume: 16, P: 1-17
A systematic review of digital and imaging technologies for measuring fatigue in immune mediated inflammatory diseases

Haley Mozier
Philip S. Murphy
Hung Nguyen
ResearchOpen Access07 Mar 2025
npj Digital Medicine

Volume: 8, P: 1-8
Elranatamab in relapsed or refractory multiple myeloma: the MagnetisMM-1 phase 1 trial

In the first-in-human trial of elranatamab, patients with refractory or relapsed multiple myeloma who received the bispecific antibody against BCMA and CD3 experienced no dose-limiting toxicities during dose escalation, and the agent showed promising clinical efficacy.

Nizar J. Bahlis
Caitlin L. Costello
Alexander M. Lesokhin
ResearchOpen Access02 Oct 2023
Nature Medicine

Volume: 29, P: 2570-2576
US threat to end science agreement with India over patent law

new delhi
The United States is threatening not to renew its science and technology agreement with India if the Indian government fails to amend its patent law to provide additional protection for intellectual property rights.

K. S. Jayaraman
News05 Jun 1997
Nature

Volume: 387, P: 540
Safety and anti-tumour activity of the IgE antibody MOv18 in patients with advanced solid tumours expressing folate receptor-alpha: a phase I trial

IgE antibodies have shown anti-tumor activity, even superior to IgG, in preclinical models. However, all monoclonal antibodies in clinical use for cancer therapy are members of the IgG class. Here the authors report the results of a phase I clinical trial of a chimeric monoclonal IgE antibody, specific for the folate receptor-alpha, in patients with advanced solid cancer.

James Spicer
Bristi Basu
Sophia N. Karagiannis
ResearchOpen Access25 Jul 2023
Nature Communications

Volume: 14, P: 1-11
A sex-specific reconstitution bias in the competitive CD45.1/CD45.2 congenic bone marrow transplant model

Salema Jafri
Stephen D. Moore
Mark L. Ormiston
ResearchOpen Access14 Jun 2017
Scientific Reports

Volume: 7, P: 1-8
Biomimetic assemblage of nucleobase 5-fluorouracil into nano-size three-dimensional particles

Arun Chauhan
Swaleha Zubair
Mohammad Owais
ResearchOpen Access04 Aug 2011
Nature Precedings

P: 1
Evaluation of highly conserved Burkholderia pseudomallei outer membrane proteins as protective antigens against respiratory melioidosis

Alexander J. Badten
Susana Oaxaca-Torres
Alfredo G. Torres
ResearchOpen Access06 Aug 2025
npj Vaccines

Volume: 10, P: 1-16
Bulk density of asteroid 243 Ida from the orbit of its satellite Dactyl

M. J. S. Belton
C. R. Chapman
B. Zellner
Research27 Apr 1995
Nature

Volume: 374, P: 785-788
Disrupted alternative splicing for genes implicated in splicing and ciliogenesis causes PRPF31 retinitis pigmentosa

Mutations in pre-mRNA processing factors cause autosomal dominant retinitis pigmentosa. Here the authors provide insights into the pathophysiological mechanisms underlying non-syndromic retinal disease caused by heterozygous mutations in genes encoding ubiquitously expressed splicing factors.

Adriana Buskin
Lili Zhu
Majlinda Lako
ResearchOpen Access12 Oct 2018
Nature Communications

Volume: 9, P: 1-19
Traceless cysteine-linchpin enables precision engineering of lysine in native proteins

Controlling the selectivity of the chemical modification of a genetic-manipulation-free protein is currently problematic. Here the authors report a method using cysteine-based chemoselective Linchpin Directed site-selective Modification of the lysine residue in a protein.

Neelesh C. Reddy
Rajib Molla
Vishal Rai
ResearchOpen Access13 Oct 2022
Nature Communications

Volume: 13, P: 1-15
Bacterial communities varied in different Coccinella transversoguttata populations located in Tibetan plateau

Huanhuan Zhang
Kun Yang
ResearchOpen Access26 Jun 2024
Scientific Reports

Volume: 14, P: 1-9
Synaptotagmin 17 controls neurite outgrowth and synaptic physiology via distinct cellular pathways

The functional role of synaptotagmin-17 (syt-17) has remained unanswered. In this study, authors demonstrate that syt-17 exists in two distinct pools in hippocampal neurons (Golgi complex and early endosomes), where it served two completely independent functions: controlling neurite outgrowth and synaptic physiology

David A. Ruhl
Ewa Bomba-Warczak
Edwin R. Chapman
ResearchOpen Access06 Aug 2019
Nature Communications

Volume: 10, P: 1-14
Giant synaptosomes

J. A. Umbach
C. B. Gundersen
P. F. Baker
Research04 Oct 1984
Nature

Volume: 311, P: 474-477
Direct interaction of Ras and the amino-terminal region of Raf-1 in vitro

Patricia H. Warne
Pablo Rodrigueza Vician
Julian Downward
Research22 Jul 1993
Nature

Volume: 364, P: 352-355
Probing the phagolysosomal environment of human macrophages with a Ca²⁺-responsive operon fusion in Yersinia pestis

Charles Pollack
Susan C. Straley
Mark S. Klempner
Research28 Aug 1986
Nature

Volume: 322, P: 834-836
Antibiotic resistance genes in the gut microbiota of mothers and linked neonates with or without sepsis from low- and middle-income countries

Analysis of gut microbiota of mothers and its neonates—as part of the BARNARDS study—reveals associations between β-lactamase gene carriage and neonatal sepsis risk in low-income settings.

M. J. Carvalho
K. Sands
T. R. Walsh
ResearchOpen Access04 Aug 2022
Nature Microbiology

Volume: 7, P: 1337-1347
The role of turns in the structure of an α-helical protein

Adam P. Brunet
Enoch S. Huang
Michael H. Hecht
Research22 Jul 1993
Nature

Volume: 364, P: 355-358
Geochemistry of Holocene volcanic rocks associated with ridge subduction in Baja California, Mexico

G. Rogers
A. D. Saunders
G. F. Marriner
Research30 May 1985
Nature

Volume: 315, P: 389-392
Permeabilities of Precambrian Onverwacht Cherts and Other Low Permeability Rocks

S. K. SANYAL
K. A. KVENVOLDEN
S. S. MARSDEN JUN.
Research30 Jul 1971
Nature

Volume: 232, P: 325-327
Direct spectroscopic observation of quantum jumps of a single molecule

Th. Basché
S. Kummer
C. Bräuchle
Research12 Jan 1995
Nature

Volume: 373, P: 132-134
Adduct-based p-doping of organic semiconductors

Adducts of dimethyl sulfoxide and hydrobromic acid demonstrate efficient p-doping of various organic semiconductors and compatibility with other counterions used to improve stability and other performance parameters of organic-based optoelectronic devices.

Nobuya Sakai
Ross Warren
Henry J. Snaith
Research22 Apr 2021
Nature Materials

Volume: 20, P: 1248-1254

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