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Showing 51–100 of 232 results

Advanced filters: Author: S D Soni Clear advanced filters

The impact of exercise on gene regulation in association with complex trait genetics

It is known that exercise influences many human traits, but not which tissues and genes are most important. This study connects transcriptome data collected across 15 tissues during exercise training in rats as part of the Molecular Transducers of Physical Activity Consortium with human data to identify traits with similar tissue specific gene expression signatures to exercise.

Nikolai G. Vetr
Nicole R. Gay
Stephen B. Montgomery
ResearchOpen Access01 May 2024
Nature Communications

Volume: 15, P: 1-14
AI generated annotations for Breast, Brain, Liver, Lungs, and Prostate cancer collections in the National Cancer Institute Imaging Data Commons

Gowtham Krishnan Murugesan
Diana McCrumb
Jeff Van Oss
ResearchOpen Access29 Jul 2025
Scientific Data

Volume: 12, P: 1-8
Visualization of CO₂ electrolysis using optical coherence tomography

Electrolysers can upgrade CO₂ into high-value chemicals, but there are few tools capable of tracking the reactions that occur within these devices during operation. Now an electrolysis optical coherence tomography platform has been developed to visualize the electrochemical conversion of CO₂ to CO, plus the movement of components, within the device.

Xin Lu
Chris Zhou
Curtis P. Berlinguette
Research01 Mar 2024
Nature Chemistry

Volume: 16, P: 979-987
Predicting opioid consumption after surgical discharge: a multinational derivation and validation study using a foundation model

Chris Varghese
Luke Peters
Caroline Reinke
ResearchOpen Access26 Aug 2025
npj Digital Medicine

Volume: 8, P: 1-16
Measurement of the inelastic proton–proton cross-section at √s=7 TeV with the ATLAS detector

The measurement of the total cross-section of proton–proton collisions is of fundamental importance for particle physics. Here, the first measurement of the inelastic cross-section is presented for proton–proton collisions at an energy of 7 teraelectronvolts using the ATLAS detector at the Large Hadron Collider.

G. Aad
B. Abbott
L. Zwalinski
ResearchOpen Access06 Sept 2011
Nature Communications

Volume: 2, P: 1-14
Functional mechanisms underlying pleiotropic risk alleles at the 19p13.1 breast–ovarian cancer susceptibility locus

A region on chromosome 19p13 is associated with the risk of developing ovarian and breast cancer. Here, the authors genotyped SNPs in this region in thousands of breast and ovarian cancer patients and identified SNPs associated with three genes, which were analysed with functional studies.

Kate Lawrenson
Siddhartha Kar
Simon A. Gayther
ResearchOpen Access07 Sept 2016
Nature Communications

Volume: 7, P: 1-22
Therapeutic potential of KLF2-induced exosomal microRNAs in pulmonary hypertension

Pulmonary arterial hypertension is a severe lung disease characterised by progressive vascular remodelling. Here, the authors show that reduced signalling of flow-activated transcription factor KLF2 is a common feature of human PAH and that KLF2-regulated exosomal miRNAs have a therapeutic effect.

Hebah A. Sindi
Giusy Russomanno
Beata Wojciak-Stothard
ResearchOpen Access04 Mar 2020
Nature Communications

Volume: 11, P: 1-17
Single-cell analysis of peripheral blood from high-altitude pulmonary hypertension patients identifies a distinct monocyte phenotype

Single cell transcriptomic sequencing (scRNA) can identify genes that are differentially expressed in cell populations in specific diseases. Here the authors perform scRNA sequencing in a high-altitude pulmonary hypertension (HAPH) cohort and show transcriptional differences in monocyte populations.

Xin-Hua Wu
Yang-Yang He
Zhi-Cheng Jing
ResearchOpen Access31 Mar 2023
Nature Communications

Volume: 14, P: 1-14
The Effect of Hybridoma Antibody Administration upon Neutrophil Kinetics during Experimental Type III Group B Streptococcal Sepsis

Robert D Christensen
Gerald Rothstein
Seth H Pincus
Research01 Oct 1983
Pediatric Research

Volume: 17, P: 795-799
Enhanced performance in fusion plasmas through turbulence suppression by megaelectronvolt ions

Experiments at the Joint European Torus tokamak show improved thermal ion confinement in the presence of highly energetic ions and Alfvénic instabilities in the plasma.

S. Mazzi
J. Garcia
I. Zychor
Research30 Jun 2022
Nature Physics

Volume: 18, P: 776-782
Engineered helicase replaces thermocycler in DNA amplification while retaining desired PCR characteristics

PCR is an essential method for the amplification and manipulation of nucleic acids, but the requirement for a thermocycler limits access. Here, authors engineer a helicase to replace the heating step of PCR with enzymatic unwinding, allowing the isothermal amplification of fragments up to 6 kb.

Momčilo Gavrilov
Joshua Y. C. Yang
Taekjip Ha
ResearchOpen Access23 Oct 2022
Nature Communications

Volume: 13, P: 1-14
β-Galactosidase in Tissue Culture Derived from Human Skin and Bone Marrow: Enzyme defect in G_M1 Gangliosidosis

Howard R Sloan
B William Uhlendorf
Donald S Fredrickson
Research01 Nov 1969
Pediatric Research

Volume: 3, P: 532-537
Motile dislocations knead odd crystals into whorls

The addition of transverse forces to an ensemble of colloidal spinners induces the appearance of odd elastic crystals, featuring self-propelled defects that organize the system into a ‘self-kneading’ crystal whorl state.

Ephraim S. Bililign
Florencio Balboa Usabiaga
William T. M. Irvine
Research16 Dec 2021
Nature Physics

Volume: 18, P: 212-218
Noncoding mutations cause super-enhancer retargeting resulting in protein synthesis dysregulation during B cell lymphoma progression

Whole-genome analysis of paired follicular lymphoma and double-hit lymphoma shows that lymphoma progression is accompanied by enhanced somatic mutations targeting super-enhancer-embedded promoters.

Rebecca J. Leeman-Neill
Dong Song
Uttiya Basu
ResearchOpen Access04 Dec 2023
Nature Genetics

Volume: 55, P: 2160-2174
Long-Chain 3-Hydroxyacyl-CoA Dehydrogenase Deficiency

Sandra Jackson
Kim Bartlett
Douglass M Turnbull
Research01 Apr 1991
Pediatric Research

Volume: 29, P: 406-411
Tyrosine phosphorylation-dependent and -independent associations of protein kinase C-Δ with Src family kinases in the RBL-2H3 mast cell line: regulation of Src family kinase activity by protein kinase C-δ

James S Song
Patrick G Swann
Juan Rivera
Research14 Jul 1998
Oncogene

Volume: 16, P: 3357-3368
Mitochondrial respiration in microglia is essential for response to demyelinating injury but not proliferation

Microglia rely on mitochondrial respiration to respond to demyelinating injury. However, mitochondrial respiration is not required to support microglial proliferation.

Joshua S. Stoolman
Rogan A. Grant
Navdeep S. Chandel
Research24 Jul 2024
Nature Metabolism

Volume: 6, P: 1492-1504
Nanometer-scale mapping of irreversible electrochemical nucleation processes on solid Li-ion electrolytes

Amit Kumar
Thomas M. Arruda
Sergei V. Kalinin
ResearchOpen Access08 Apr 2013
Scientific Reports

Volume: 3, P: 1-8
Text mining of outpatient narrative notes to predict the risk of psychiatric hospitalization

Vedat Verter
Fan E
Angelos Georghiou
ResearchOpen Access20 Feb 2025
Translational Psychiatry

Volume: 15, P: 1-7
Inherited Lactic Acidosis: Correction of the Defect in Cultured Fibroblasts

Paul R Goodyer
Gerald A Lancaster
Research01 Nov 1984
Pediatric Research

Volume: 18, P: 1144-1148
A cross-disease resource of living human microglia identifies disease-enriched subsets and tool compounds recapitulating microglial states

Profiling >200,000 live human microglia from 74 donors across neurological diseases reveals 12 subtypes of microglia that were validated in situ. Camptothecin is also identified as a compound reducing disease-enriched microglial subsets.

John F. Tuddenham
Mariko Taga
Philip L. De Jager
Research15 Oct 2024
Nature Neuroscience

Volume: 27, P: 2521-2537
Quantum correlations between light and the kilogram-mass mirrors of LIGO

Quantum correlations between the laser beams and the positions of the 40-kg mirrors of LIGO are confirmed experimentally, enabling high-precision measurements of both gravitational waves and macroscopic quantum states.

Haocun Yu
L. McCuller
J. Zweizig
Research01 Jul 2020
Nature

Volume: 583, P: 43-47
Unrevealing tunable resonant excitons and correlated plasmons and their coupling in new amorphous carbon-like for highly efficient photovoltaic devices

D. Darminto
Retno Asih
Andrivo Rusydi
ResearchOpen Access04 May 2023
Scientific Reports

Volume: 13, P: 1-8
Acute hypotension associated with terbutaline nebuliser therapy in a traumatic tetraplegic patient during the spinal shock phase. Case report

B M Soni
S Vaidyanathan
K R Krishnan
Research01 May 1995
Spinal Cord

Volume: 33, P: 300-301
Cis-eQTL analysis and functional validation of candidate susceptibility genes for high-grade serous ovarian cancer

Genome-wide association studies have identified regions which confer risk of high-grade serous epithelial ovarian cancer. Here the authors use expression quantitative train locus analysis to identify candidate genes and functionally characterise them, identifying a role for HOXD9 in ovarian cancer.

Kate Lawrenson
Qiyuan Li
Matthew L. Freedman
ResearchOpen Access22 Sept 2015
Nature Communications

Volume: 6, P: 1-14
The SUV4-20 inhibitor A-196 verifies a role for epigenetics in genomic integrity

SUV4-20 members mediate the di- and trimethylation of lysine 20 on histone H4. A chemical screen led to the identification of A-196 as a potent and selective inhibitor of SUV4-20 that decreases H4K20 methylation and alters DNA damage response.

Kenneth D Bromberg
Taylor R H Mitchell
William N Pappano
Research23 Jan 2017
Nature Chemical Biology

Volume: 13, P: 317-324
Identification and molecular characterization of a new ovarian cancer susceptibility locus at 17q21.31

Most confirmed susceptibility variants for epithelial ovarian cancer lie in non-protein-coding sequences. Here Permuth-Wey and colleagues investigate variants in 3′ untranslated regions (UTRs) and uncover a new susceptibility locus.

Jennifer Permuth-Wey
Kate Lawrenson
Simon A. Gayther
ResearchOpen Access27 Mar 2013
Nature Communications

Volume: 4, P: 1-12
Discussion

L S Michaelis
Research01 Aug 1970
Spinal Cord

Volume: 8, P: 67-69
1609 POST-NEONATAL HYPERTENSION SCREENING IN NICU GRADUATES WHO HAVE HAD INDWELLING UMBILICAL ARTERY (UA) CATHETERS

V Karotorn
A Koons
R Rapkin
Research01 Apr 1985
Pediatric Research

Volume: 19, P: 379
CEP162 is an axoneme-recognition protein promoting ciliary transition zone assembly at the cilia base

Axonemal microtubules are crosslinked to the surrounding plasma membrane at the ciliary base, in the transition zone. Tsou and colleagues have identified a centriole distal-end protein, CEP162, which mediates the association of transition zone components to axonemal microtubules.

Won-Jing Wang
Hwee Goon Tay
Meng-Fu Bryan Tsou
Research05 May 2013
Nature Cell Biology

Volume: 15, P: 591-601
Structural, elastic, electronic, optical and anisotropy properties of newly quaternary Tl2HgGeSe4 via DFPT predictions associated to XPES and RS experiments

Mohamed Salah Halati
Oleg Yu Khyzhun
Sherif S. M. Ghoneim
ResearchOpen Access15 Jul 2024
Scientific Reports

Volume: 14, P: 1-23
Analysis of candidate imprinted genes in PWS subjects with atypical genetics: a possible inactivating mutation in the SNURF/SNRPN minimal promoter

Esther N. Maina
Tessa Webb
Anthony Holland
Research30 Jan 2007
Journal of Human Genetics

Volume: 52, P: 297-307
Genetic polymorphism of MUC7: Allele frequencies and association with asthma

Helen J Kirkbride
Jan G Bolscher
Dallas M Swallow
Research21 Jun 2001
European Journal of Human Genetics

Volume: 9, P: 347-354
Transposon-encoded CRISPR–Cas systems direct RNA-guided DNA integration

A programmable transposase integrates donor DNA at user-defined genomic target sites with high fidelity, revealing a new approach for genetic engineering that obviates the need for DNA double-strand breaks and homologous recombination.

Sanne E. Klompe
Phuc L. H. Vo
Samuel H. Sternberg
Research12 Jun 2019
Nature

Volume: 571, P: 219-225
Enhanced aerosol particle growth sustained by high continental chlorine emission in India

Half of the reduced visibility due to haze formation in cities in India is attributed to local emission of gas-phase hydrochloric acid from waste-burning and industry, according to measurements of particulate matter and thermodynamic modelling.

Sachin S. Gunthe
Pengfei Liu
Hugh Coe
Research25 Jan 2021
Nature Geoscience

Volume: 14, P: 77-84
Epigenetic analysis leads to identification of HNF1B as a subtype-specific susceptibility gene for ovarian cancer

HNF1B is overexpressed in the clear cell subtype and epigenetically silenced in the serous subtype of ovarian cancer. Pearce and colleagues now show that genetic variants in HNF1B are differentially associated with risks of developing these two cancer subtypes, possibly through an epigenetic mechanism.

Hui Shen
Brooke L. Fridley
Celeste Leigh Pearce
ResearchOpen Access27 Mar 2013
Nature Communications

Volume: 4, P: 1-10
van der Waals driven anharmonic melting of the 3D charge density wave in VSe₂

The nature of the charge density wave transition in VSe₂ is still debated. Here, the authors demonstrate that the transition is mainly driven by electron-phonon interactions, despite the presence of the Fermi-surface nesting, and that Wan-der-Waals forces are responsible for melting of the charge density wave order.

Josu Diego
A. H. Said
S. Blanco-Canosa
ResearchOpen Access26 Jan 2021
Nature Communications

Volume: 12, P: 1-7
Ensuring meiotic DNA break formation in the mouse pseudoautosomal region

In mice, the pseudoautosomal region of the sex chromosomes undergoes a dynamic structural rearrangement to promote a high rate of DNA double-strand breaks and to ensure X–Y recombination.

Laurent Acquaviva
Michiel Boekhout
Scott Keeney
Research27 May 2020
Nature

Volume: 582, P: 426-431
The morbidity due to lower urinary tract function in spinal cord injury patients

P E V Van Kerrebroeck
E L Koldewijn
F M J Debruyne
Research01 May 1993
Spinal Cord

Volume: 31, P: 320-329
Exaggerated neurological side-effects of oral and intravesical oxybutynin in a patient with multiple sclerosis

S Vaidyanathan
K R Krishnan
M H Fraser
Research01 Mar 1997
Spinal Cord

Volume: 35, P: 190
Omental Transposition in Chronic Spinal Cord Injury

H S Goldsmith
Research01 Mar 1997
Spinal Cord

Volume: 35, P: 189
Association study of major risk single nucleotide polymorphisms in the common regulatory region of PARK2 and PACRG genes with leprosy in an Indian population

Dheeraj Malhotra
Katayoon Darvishi
Ramesh N K Bamezai
Research14 Dec 2005
European Journal of Human Genetics

Volume: 14, P: 438-442
Antibiotic-driven boosting of oncolytic virotherapy

Oncolytic viruses expressing transgenes for immunomodulatory cytokines can be produced at high throughput by exploiting the preferential susceptibility of the viruses to certain antibiotics.

Himanshu Soni
E. Antonio Chiocca
Joshua D. Bernstock
News & Views28 Nov 2024
Nature Biomedical Engineering

Volume: 9, P: 793-794
The British Association at Bournemouth. Section D. Zoology: Opening Address

F. A. DIXEY
News09 Oct 1919
Nature

Volume: 104, P: 121-126
Harnessing optimization with deep learning approach on intelligent transportation system for anomaly detection in pedestrian walkways

Sultan Refa Alotaibi
Fatma S. Alrayes
Moneerah Alotaibi
ResearchOpen Access19 May 2025
Scientific Reports

Volume: 15, P: 1-28
Risk factors for intellectual and educational sequelae of cranial irradiation in childhood acute lymphoblastic leukaemia

E Smibert
V Anderson
H Ekert
Research01 Mar 1996
British Journal of Cancer

Volume: 73, P: 825-830
Vesical urothelium proliferation in spinal cord injured persons: an immunohistochemical study of PCNA and MIB.1 labelling

D van Velzen
K R Krishnan
S Vaidyanathan
Research01 Sept 1995
Spinal Cord

Volume: 33, P: 523-529
Comparative analysis of the diagnostic performance of five commercial COVID-19 qRT PCR kits used in India

J. Singh
A. K. Yadav
S. Singh
ResearchOpen Access10 Nov 2021
Scientific Reports

Volume: 11, P: 1-8
Publisher Correction: An Artificial Intelligence-guided signature reveals the shared host immune response in MIS-C and Kawasaki disease

Pradipta Ghosh
Gajanan D. Katkar
Debashis Sahoo
Amendments and CorrectionsOpen Access11 Aug 2022
Nature Communications

Volume: 13, P: 1
Transcriptional regulator-induced phenotype screen reveals drug potentiators in Mycobacterium tuberculosis

In this study, the authors use a transcriptional regulator-induced phenotype screen coupled with network analysis to characterize adaptations of Mycobacterium tuberculosis to the first-line anti-tuberculosis drug isoniazid. They identify the transcriptional factor mce3R and the CtpD effector to have a role in Mycobacterium susceptibility to isoniazid.

Shuyi Ma
Robert Morrison
David R. Sherman
Research16 Nov 2020
Nature Microbiology

Volume: 6, P: 44-50

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