Nature Search

Microglia-specific regulation of lipid metabolism in Alzheimer’s disease revealed by microglial depletion in 5xFAD Mice

Alzheimer’s disease disrupts brain lipid metabolism; while microglia are likely implicated, the relationship is unclear. Here, the authors show that microglia selectively regulate lysosomal and myelin lipids, but other lipid changes occur independently of microglia.

Ziying Xu
Sepideh Kiani Shabestari
Xianlin Han
ResearchOpen Access15 Oct 2025
Nature Communications

Volume: 16, P: 1-16
Nature of Reticulin

D. S. JACKSON
G. WILLIAMS
Research27 Oct 1956
Nature

Volume: 178, P: 915-916
The Origin of the Cultivated Cineraria

W. BATESON
Research09 May 1895
Nature

Volume: 52, P: 29
The Origin of the Cultivated Cineraria

W. BATESON
Research30 May 1895
Nature

Volume: 52, P: 103-104
Aboveground Net Primary Productivity in Grazed and Ungrazed pastures: Grazing Optimisation Hypothesis or Local Extinction of Vegetation Species

Silvanus Otieno
Jesse Njoka
Robinson Ngugi
ResearchOpen Access23 Jul 2009
Nature Precedings

P: 1
Adipocyte associated glucocorticoid signaling regulates normal fibroblast function which is lost in inflammatory arthritis

Fibroblasts play critical roles in tissue homeostasis, but in pathologic states they can drive fibrosis, inflammation, and tissue destruction. Here, Faust et al. find that healthy human synovial fibroblasts under the influence of adjacent adipocytes have altered lipid metabolism driven by cortisol signaling. Both adipocytes and these characteristics are lost in inflammatory arthritis.

Heather J. Faust
Tan-Yun Cheng
Michael B. Brenner
ResearchOpen Access14 Nov 2024
Nature Communications

Volume: 15, P: 1-20
Stratospheric Transport of Volcanic Dust Inferred from Solar Radiation Measurements

A. J. DYER
B. B. HICKS
Research09 Oct 1965
Nature

Volume: 208, P: 131-133
The Origin of the Cultivated Cineraria

W. BATESON
Research25 Apr 1895
Nature

Volume: 51, P: 605-607
Basalt magma sources during the opening of the North Atlantic

S. R. Carter
N. M. Evensen
R. K. O'Nions
Research01 Sept 1979
Nature

Volume: 281, P: 28-30
Mycoplasma bovis pneumonia in marsh deer (Blastocerus dichotomus) from a natural reserve of Argentina

D. Balbuena
C. Margineda
JA García
ResearchOpen Access30 Sept 2025
Scientific Reports

Volume: 15, P: 1-6
Apomixis may be widespread among trees of the climax rain forest

A. KAUR
C. O. HA
P. S. ASHTON
Research02 Feb 1978
Nature

Volume: 271, P: 440-442
LpxI structures reveal how a lipid A precursor is synthesized

In Gram-negative bacterial outer membranes, lipid A serves as the anchor for lipopolysaccharide. Structural and biochemical data reveal that LpxI, an enzyme involved in lipid A synthesis, uses a hinge-like mechanism to deposit its product into the membrane through the binding of fresh substrate.

Louis E Metzger IV
John K Lee
Robert M Stroud
Research07 Oct 2012
Nature Structural & Molecular Biology

Volume: 19, P: 1132-1138
E. coli membrane lipid alteration affecting T4 capsid morphogenesis

Lee D. Simon
Thomas J. M. McLaughlin
Marilyn Loeb
Research31 Jul 1975
Nature

Volume: 256, P: 379-383
A diverse proteome is present and enzymatically active in metabolite extracts

Metabolite extraction with organic solvents is assumed to remove/denature proteins. Here, the authors uncover a vast landscape of >1,000 proteins in metabolite extracts. These proteins can retain catalytic activity and drive post-extraction metabolite changes, obscuring biological interpretation.

Rachel (Rae) J. House
Molly T. Soper-Hopper
Ryan D. Sheldon
ResearchOpen Access10 Jul 2024
Nature Communications

Volume: 15, P: 1-17
Meridional interactions between rainfall and surface pressure

T. G. J. DYER
Research04 Nov 1976
Nature

Volume: 264, P: 48-49
Boltzmann's Minimum Function

S. H. BURBURY
Research30 May 1895
Nature

Volume: 52, P: 104-105
Towards definitive functional forms for Monin–Obukhov similarity functions in stable and very stable surface layers

G. Casasanta
M. Conte
S. Argentini
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-17
Experimental Observations on the Structure of Collisionless Shock Waves in a Magnetized Plasma

J. W. M. PAUL
L. S. HOLMES
J. SHEFFIELD
Research09 Oct 1965
Nature

Volume: 208, P: 133-135
Hyperlipaemia Following Viral Infection in the Chicken Embryo: A New Syndrome

S. E. GROSSBERG
W. M. O'LEARY
Research04 Dec 1965
Nature

Volume: 208, P: 954-956
Observations on the Production of Mesons by Cosmic Radiation

G. P. S. OCCHIALINI
C. F. POWELL
Research31 Jul 1948
Nature

Volume: 162, P: 168-173
Charge states of the vacancy in diamond

GORDON DAVIES
Research01 Oct 1977
Nature

Volume: 269, P: 498-500
Separation of Strontium from Milk and Protein Solutions by Gel Filtration

W. H. S. GEORGE
Research14 Jul 1962
Nature

Volume: 195, P: 155-157
Fluorescent Whitening Agents

R. S. HIGGINBOTHAM
F. W. THOMAS
Research24 May 1958
Nature

Volume: 181, P: 1437-1439
Science and Government

A. T. S.
Research03 Oct 1907
Nature

Volume: 76, P: 565-566
VLBI structures of the images of the double QSO 0957 + 561

R. W. Porcas
R. S. Booth
P. N. Wilkinson
Research26 Feb 1981
Nature

Volume: 289, P: 758-762
Nitrogen and phosphorus differentially control marine biomass production and stoichiometry

Mesocosm experiments revealed that both phytoplankton community composition and cellular acclimation influence marine particulate C:N:P ratios, with community shifts more sensitive to nitrogen supply and acclimation to the nutrient N:P supply ratio

Emily A. Seelen
Samantha J. Gleich
Seth G. John
ResearchOpen Access01 Jul 2025
Nature Communications

Volume: 16, P: 1-13
Cryptorchism in Australian Merino Sheep

C. H. S. DOLLING
M. G. BROOKER
Research01 Jul 1964
Nature

Volume: 203, P: 49-50
Selective Extraction of a Protein Fraction from Wool Keratin

R. A. DEDEURWAERDER
M. G. DOBB
B. J. SWEETMAN
Research01 Jul 1964
Nature

Volume: 203, P: 48-49
A Pot of Basil

A. E. SHIPLEY
Research01 Jan 1903
Nature

Volume: 67, P: 205-206
The Draper Catalogue

EDWARD C. PICKERING
Research09 Jul 1891
Nature

Volume: 44, P: 223
The Stock of Antarctic Blue Whales

ALEC H. LAURIE
Research04 Jul 1936
Nature

Volume: 138, P: 33
Seasonal Variations of Cæsium-137 in Air at Ground-Level

K. G. VOHRA
V. S. BHATNAGAR
C. RANGARAJAN
Research19 Aug 1961
Nature

Volume: 191, P: 747-748
Flow Patterns in a Submerged Liquid Jet Diffusing Under Gravity

S. K. A. NAIB
Research14 May 1966
Nature

Volume: 210, P: 694-695
The role of alpha-synuclein in synucleinopathy: Impact on lipid regulation at mitochondria–ER membranes

Peter A. Barbuti
Cristina Guardia-Laguarta
Serge Przedborski
ResearchOpen Access30 Apr 2025
npj Parkinson's Disease

Volume: 11, P: 1-15
Relationship of the Velocity of a Charged Particle to its Relative Biological Effectiveness

J. E. TURNER
HAL HOLLISTER
Research01 Oct 1965
Nature

Volume: 208, P: 36-37
An engineered ribonuclease preferring phosphorothioate RNA

Stefan Loverix
Anna Winquist
Jan Steyaert
Research01 May 1998
Nature Structural Biology

Volume: 5, P: 365-368
NanoVar: a comprehensive workflow for structural variant detection to uncover the genome’s hidden patterns

NanoVar is a structural variant caller for low-depth long-read sequencing data, allowing repeat element annotation of non-reference insertion variants. This is a comprehensive guide, from quality assessment of raw data to downstream analysis.

Asmaa Samy
Cheng Yong Tham
Touati Benoukraf
Protocols01 Oct 2025
Nature Protocols

P: 1-26
Selective lipid recruitment by an archaeal DPANN symbiont from its host

The symbiont Ca. Nanohaloarchaeum antarcticus is dependent on its host Halorubrum lacusprofundi for lipids due to a lack of certain biosynthetic genes. Here, the authors characterize the lipidome dynamics of this symbiotic relationship.

Su Ding
Joshua N. Hamm
Anja Spang
ResearchOpen Access22 Apr 2024
Nature Communications

Volume: 15, P: 1-13
The Aneroid in Hypsometry.

HERBERT TOMLINSON
Research10 Mar 1892
Nature

Volume: 45, P: 440-441
Dominant control of temperature on (sub-)tropical soil carbon turnover

Soil-carbon turnover in the Nile River basin accelerated by an order of magnitude due to post-glacial warming and led to release of CO₂ into the atmosphere. Its temperature sensitivity is higher than expected with implications for future warming.

Vera D. Meyer
Peter Köhler
Enno Schefuß
ResearchOpen Access15 May 2025
Nature Communications

Volume: 16, P: 1-12
Microbial physiology conserves phosphorus across long-term ecosystem development

Microbial physiology conserves phosphorus by reducing phosphorus contributions in membrane lipids and increasing intracellular carbon storage during long-term ecosystem development, according to measurements of a ~700,000–year chronosequence across an Australian dune system.

O. M. Butler
S. Manzoni
C. R. Warren
ResearchOpen Access12 May 2025
Nature Geoscience

Volume: 18, P: 503-509
Comment on “Non-Velocity Redshifts and Photon-Photon Interactions”

R. ALDROVANDI
S. CASER
R. OMNÉS
Research02 Feb 1973
Nature

Volume: 241, P: 340-341
Colour-Associations with Numerals, &c

EDWARD S. HOLDEN
Research09 Jul 1891
Nature

Volume: 44, P: 223-224
HLA antigens and cervical carcinoma

SUSAN S. GLEW
PETER L. STERN
PHILIP A. DYER
Research05 Mar 1992
Nature

Volume: 356, P: 22
Toxicity of Erythromycin

W. D. TIGERTT
W. S. GOCHENOUR JUN.
Research21 Dec 1957
Nature

Volume: 180, P: 1429-1430
Sea-sickness and Equilibration of the Eyes

ALFRED SANG
Research29 Mar 1906
Nature

Volume: 73, P: 511-512
Photocatalytic oxidation of tyrosine using colloidal CdS particles under visible light irradiation

Pratigya Rizal
Devendra P. S. Negi
ResearchOpen Access26 Jul 2025
Scientific Reports

Volume: 15, P: 1-8
Structure and mechanism of biosynthesis of Streptococcus mutans cell wall polysaccharide

The cell wall of the oral bacterium Streptococcus mutans carries SCC, a rhamnose-containing polysaccharide with glucose side-chain decorations. Here, the authors report the SCC structure and the synthesis mechanism, revealing how four glucosyltransferases work together to synthesize the side-chains.

Jeffrey S. Rush
Svetlana Zamakhaeva
Natalia Korotkova
ResearchOpen Access22 Jan 2025
Nature Communications

Volume: 16, P: 1-16
GRAMD1B is a regulator of lipid homeostasis, autophagic flux and phosphorylated tau

The relationship between lipid dyshomeostasis and tau pathology in FTLD and AD remains unclear. Here, the authors demonstrate that GRAMD1B contributes to lipid dyshomeostasis, autophagy impairment, and tau hyperphosphorylation in neurons.

Diana Acosta Ingram
Emir Turkes
Hongjun Fu
ResearchOpen Access09 Apr 2025
Nature Communications

Volume: 16, P: 1-24
Asgard Arf GTPases can act as membrane-associating molecular switches with the potential to function in organelle biogenesis

The formation of organelles was a pivotal point in eukaryotic evolution. Here they show that Archaea possess Arf-like GTPases that can perform key organelle-producing mechanisms when expressed in a eukaryotic cell, laying the foundation for the evolution of endomembrane organelles.

Jing Zhu
Ruize Xie
Zhiping Xie
ResearchOpen Access17 Mar 2025
Nature Communications

Volume: 16, P: 1-14

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