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Showing 151–200 of 360 results

Advanced filters: Author: S G Naylor Clear advanced filters

Disease and development

Michael A. Walter
Peter N. Goodfellow
News & Views13 Feb 1992
Nature

Volume: 355, P: 590-591
ID4 controls mammary stem cells and marks breast cancers with a stem cell-like phenotype

Basal-like breast cancer is a heterogeneous disease with poor prognosis; however, its cellular origins and aetiology are poorly understood. Here the authors provide evidence that ID4 is a key controller of mammary stem/progenitor cell self-renewal, acting upstream of Notch signalling to repress luminal fate commitment.

Simon Junankar
Laura A. Baker
Alexander Swarbrick
Research27 Mar 2015
Nature Communications

Volume: 6, P: 1-12
Identification of Methyl-branched Chain Dicarboxylic Acids in Amniotic Fluid and Urine in Propionic and Methylmalonic Acidemia

Cornelis Jakobs
Lambertus Dorland
Sybe K Wadman
Research01 Nov 1984
Pediatric Research

Volume: 18, P: 1185-1191
Medium Chain Acyl-CoA Dehydrogenase Deficiency in Pennsylvania: Neonatal Screening Shows High Incidence and Unexpected Mutation Frequencies

Rana Ziadeh
Eric P Hoffman
Edwin W Naylor
Research01 May 1995
Pediatric Research

Volume: 37, P: 675-678
Compound climate risks threaten aquatic food system benefits

The nutritional, economic and livelihood contributions provided by aquatic food systems are threatened by climate change. Building climate resilience requires systemic interventions that reduce social vulnerabilities.

Michelle Tigchelaar
William W. L. Cheung
Max Troell
Research15 Sept 2021
Nature Food

Volume: 2, P: 673-682
Genome sequence, comparative analysis and haplotype structure of the domestic dog

Kerstin Lindblad-Toh
Claire M Wade
Eric S. Lander
Research08 Dec 2005
Nature

Volume: 438, P: 803-819
TLCD1 and TLCD2 regulate cellular phosphatidylethanolamine composition and promote the progression of non-alcoholic steatohepatitis

The regulation of cellular phosphatidylethanolamine (PE) acyl chain composition is poorly understood. Here, the authors show that TLCD1 and TLCD2 proteins mediate the formation of monounsaturated fatty acid-containing PE species and promote the progression of non-alcoholic steatohepatitis.

Kasparas Petkevicius
Henrik Palmgren
Xiao-Rong Peng
ResearchOpen Access14 Oct 2022
Nature Communications

Volume: 13, P: 1-14
Precision treatment of beta-cell monogenic diabetes: a systematic review

Naylor et al. systematically review the efficacy of treatments for beta-cell monogenic diabetes. Limited evidence from the mostly non-randomized, small studies supports no treatment in glucokinase-related hyperglycemia and sulfonylureas for HNF1A-diabetes; further evidence is needed on the optimum treatments in these and other monogenic subtypes.

Rochelle N. Naylor
Kashyap A. Patel
Tiinamaija Tuomi
ResearchOpen Access18 Jul 2024
Communications Medicine

Volume: 4, P: 1-17
C₆—C₁₀-Dicarboxylic Aciduria: Investigations of a Patient with Riboflavin Responsive Multiple Acyl-CoA Dehydrogenation Defects

N Gregersen
H Wintzensen
K Rasmussen
Research01 Oct 1982
Pediatric Research

Volume: 16, P: 861-868
Loss-of-function mutations in a calcium-channel α₁-subunit gene in Xp11.23 cause incomplete X-linked congenital stationary night blindness

N. Torben Bech-Hansen
Margaret J. Naylor
Kym M. Boycott
Research01 Jul 1998
Nature Genetics

Volume: 19, P: 264-267
Structure of the key toxin in gas gangrene

Claire E. Naylor
Julian T. Eaton
Ajit K. Basak
Research01 Aug 1998
Nature Structural Biology

Volume: 5, P: 738-746
The World Population Conference

A. M. C.-S.
News01 Oct 1927
Nature

Volume: 120, P: 465-466
Analysis of the DNA sequence and duplication history of human chromosome 15

An analysis of human chromosome 15 — which is altered in Prader-Willi and Angelman syndromes — reveals that it resembles a hall of mirrors, as it contains a number of sequence duplications throughout its length. The evolutionary events that may have led to the high number of duplications was also reconstructed.

Michael C. Zody
Manuel Garber
Chad Nusbaum
Research30 Mar 2006
Nature

Volume: 440, P: 671-675
Farming is in the blood

J. S. Jones
News & Views09 May 1991
Nature

Volume: 351, P: 97-98
Role of the C-terminal domain in the structure and function of tetrameric sodium channels

Prokaryotic voltage-gated sodium channels possess dynamically disordered cytoplasmic C-terminal domains. Bagnéris et al. present the structure of the Magnetococcus marinusNavMs pore and C-terminal domain and reveal its role in coupling channel inactivation and opening.

Claire Bagnéris
Paul G. DeCaen
B. A. Wallace
ResearchOpen Access19 Sept 2013
Nature Communications

Volume: 4, P: 1-10
Analysis of Brca1-deficient mouse mammary glands reveals reciprocal regulation of Brca1 and c-kit

C E Smart
A Wronski
M A Brown
ResearchOpen Access06 Dec 2010
Oncogene

Volume: 30, P: 1597-1607
Congenital oculomotor palsy: Associated neurological and ophthalmological findings

M D Tsaloumas
H E Willshaw
Research01 Jul 1997
Eye

Volume: 11, P: 500-503
Reduced neural selectivity for mental states in deaf children with delayed exposure to sign language

Early linguistic experience directly facilitates social development in childhood. Here, the authors reveal that children with delayed access to language show delayed development of selective responses in cortical regions involved in thinking about others’ thoughts.

Hilary Richardson
Jorie Koster-Hale
Rebecca Saxe
ResearchOpen Access26 Jun 2020
Nature Communications

Volume: 11, P: 1-13
myo-Inositol: A Newly Identified Nonnitrogenous Osmoregulatory Molecule in Mammalian Brain

Jean Holowach Thurston
William R Sherman
Robert F Kloepper
Research01 Nov 1989
Pediatric Research

Volume: 26, P: 482-485
A novel R198H mutation in the glucose-6-phosphate dehydrogenase gene in the tribal groups of the Nilgiris in Southern India

R. Chalvam
P. S. Kedar
M. B. Mukherjee
Research01 Feb 2008
Journal of Human Genetics

Volume: 53, P: 181-184
Second international consensus report on gaps and opportunities for the clinical translation of precision diabetes medicine

A systematic review of evidence, across the key pillars of prevention, diagnosis, treatment and prognosis, outlines milestones that need to be met to enable the broad clinical implementation of precision medicine in diabetes care.

Deirdre K. Tobias
Jordi Merino
Paul W. Franks
Reviews05 Oct 2023
Nature Medicine

Volume: 29, P: 2438-2457
Changes in wet bulb globe temperature and risk to heat-related hazards in Bangladesh

A. S. M. Maksud Kamal
Abul Kashem Faruki Fahim
Shamsuddin Shahid
ResearchOpen Access06 May 2024
Scientific Reports

Volume: 14, P: 1-19
Inhibition by Lithium of Cyclic GMP Formation without Inhibition of Nitric Oxide Generation in the Mouse Neuroblastoma Cell (N1E-115)

Futoshi Shintani
Shigenobu Kanba
Masahiro Asai
Research01 Oct 1994
Neuropsychopharmacology

Volume: 11, P: 119-124
Constitutive smooth muscle tumour necrosis factor regulates microvascular myogenic responsiveness and systemic blood pressure

TNF is typically viewed as an inflammatory mediator. Here the authors identify a non-inflammatory mechanism conserved across species whereby the constitutively expressed smooth muscle cell TNF mediates myogenic signal transduction in skeletal muscle resistance arteries and regulates mean arterial blood pressure.

Jeffrey T. Kroetsch
Andrew S. Levy
Steffen-Sebastian Bolz
ResearchOpen Access05 Apr 2017
Nature Communications

Volume: 8, P: 1-14
p53 Mutations in non-small-cell lung cancers occurring in individuals without a past history of active smoking

Y Takagi
H Osada
T Takahashi
Research01 May 1998
British Journal of Cancer

Volume: 77, P: 1568-1572
High-throughput screening using patient-derived tumor xenografts to predict clinical trial drug response

The authors implement a collection of patient-derived xenograft tumors to test cancer drug responses.

Hui Gao
Joshua M Korn
William R Sellers
Research19 Oct 2015
Nature Medicine

Volume: 21, P: 1318-1325
Genome of the marsupial Monodelphis domestica reveals innovation in non-coding sequences

The genome of the grey short-tailed opossum Monodelphis domestica has been sequenced and analyzed, giving a first peek at a marsupial's genetic code. Of particular interest are the genetics of the immune system, which has been studied as a model for humans, and of the X chromosome for historical reasons.

Tarjei S. Mikkelsen
Matthew J. Wakefield
Kerstin Lindblad-Toh
Research10 May 2007
Nature

Volume: 447, P: 167-177
DNA variation and the future of human genetics

Alan J. Schafer
J. Ross Hawkins
Reviews01 Jan 1998
Nature Biotechnology

Volume: 16, P: 33-39
Enhancement of bioreductive drug toxicity in murine tumours by inhibition of the activity of nitric oxide synthase

SA Butler
PJ Wood
IJ Stratford
Research01 Aug 1997
British Journal of Cancer

Volume: 76, P: 438-444
Mutations in MKKS cause Bardet-Biedl syndrome

Anne M. Slavotinek
Edwin M. Stone
Leslie G. Biesecker
Research01 Sept 2000
Nature Genetics

Volume: 26, P: 15-16
Cellular protoonocogenes are infrequently amplified in untreated non-small cell lung cancer

RJC Slebos
SG Evers
S Rodenhuis
Research01 Jan 1989
British Journal of Cancer

Volume: 59, P: 76-80
Evolution of genes and genomes on the Drosophila phylogeny

An international consortium reports the genomic sequence for ten Drosophila species, and compares them to two other previously published Drosophila species. These data are invaluable for drawing evolutionary conclusions across an entire phylogeny of species at once.

Andrew G. Clark
Michael B. Eisen
Iain MacCallum
Research08 Nov 2007
Nature

Volume: 450, P: 203-218
Light and temperature effects on the germination of wild oats

W J Whittington
J Hillman
J C White
Research01 Nov 1970
Heredity

Volume: 25, P: 641-650
Mapping the global potential for marine aquaculture

Marine aquaculture has the potential to improve food security. A global analysis shows that space in coastal areas is unlikely to limit the potential for aquaculture.

Rebecca R. Gentry
Halley E. Froehlich
Benjamin S. Halpern
Research14 Aug 2017
Nature Ecology & Evolution

Volume: 1, P: 1317-1324
Neonatal Blood Carnitine Concentrations: Normative Data by Electrospray Tandem Mass Spectometry

Donald H Chace
Roser Pons
Darryl C De Vivo
Research01 May 2003
Pediatric Research

Volume: 53, P: 823-829
A physical map of the human genome

John D. McPherson
Marco Marra
Hans Lehrach
Research15 Feb 2001
Nature

Volume: 409, P: 934-941
Small molecule inhibitors of RAS-effector protein interactions derived using an intracellular antibody fragment

Intracellular antibodies can inhibit disease-relevant protein interactions, but inefficient cellular uptake limits their utility. Using a RAS-targeting intracellular antibody as a screening tool, the authors here identify small molecules that inhibit RAS-effector interactions and readily penetrate cells.

Camilo E. Quevedo
Abimael Cruz-Migoni
Terence H. Rabbitts
ResearchOpen Access09 Aug 2018
Nature Communications

Volume: 9, P: 1-12
Frequent gene deletions in potentially malignant oral lesions

G Emilion
JD Langdon
M Partridge
Research01 Mar 1996
British Journal of Cancer

Volume: 73, P: 809-813
Harnessing the diversity of small-scale actors is key to the future of aquatic food systems

A framework for capturing the key dimensions of small-scale actors in aquatic food supply chains is explored—with recommendations for supporting their viability and adaptability in sustainable food systems

Rebecca E. Short
Stefan Gelcich
Wenbo Zhang
Research15 Sept 2021
Nature Food

Volume: 2, P: 733-741
Using array-comparative genomic hybridization to define molecular portraits of primary breast cancers

S-F Chin
Y Wang
C Caldas
Research25 Sept 2006
Oncogene

Volume: 26, P: 1959-1970
Dinucleotide repeats negatively modulate the promoter activity of Cyr61 and is unstable in hepatocellular carcinoma patients

Baoshuang Wang
Jianwei Ren
Caroline G L Lee
Research14 Mar 2005
Oncogene

Volume: 24, P: 3999-4008
Global priorities for conserving the evolutionary history of sharks, rays and chimaeras

Evolutionary distinctness is used as a metric to determine conservation priorities across all Chondrichthyes, identifying 21 countries with the highest richness, endemism and evolutionary distinctness of threatened species as targets.

R. William Stein
Christopher G. Mull
Arne O. Mooers
Research18 Jan 2018
Nature Ecology & Evolution

Volume: 2, P: 288-298
REVRESED CHRONOBIOLOGY OF THE “DAWN PHENOMENON” IN ADRENAL HEYPERPLASTA: RESURGENCE OF THE ACTH-ADRENAL AXIS

Silva A Arslnina
Philip Starceski
Peter A Lee
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 339
Distinct fibroblast subsets drive inflammation and damage in arthritis

Distinct subsets of fibroblasts, which differ in their expression of thymus cell antigen 1 (THY1), are responsible for inflammation and tissue damage in mouse models of arthritis.

Adam P. Croft
Joana Campos
Christopher D. Buckley
Research29 May 2019
Nature

Volume: 570, P: 246-251
Non-melanoma skin cancer and solar keratoses II analytical results of the South Wales Skin Cancer Study

I Harvey
S Frankel
M Nolan-Farrell
Research01 Oct 1996
British Journal of Cancer

Volume: 74, P: 1308-1312
Novel hypergravity treatment enhances root phenotype and positively influences physio-biochemical parameters in bread wheat (Triticum aestivum L.)

Basavalingayya K. Swamy
Ravikumar Hosamani
Narayan Moger
ResearchOpen Access27 Jul 2021
Scientific Reports

Volume: 11, P: 1-16
Natural selection through maternal influence

Alfred F Naylor
Research01 Aug 1964
Heredity

Volume: 19, P: 509-511
Grade inflation effects of capacity expansion in higher education: a longitudinal study in undergraduate teacher education programs from 2003 to 2022

S. Koza Ciftci
Engin Karadag
ResearchOpen Access29 Jun 2024
Humanities and Social Sciences Communications

Volume: 11, P: 1-9
URINARY C-PEPTIDE IN NORMAL CHILDREN AND ADOLESCENTS

Gaya S Aranoff
John F Nicholson
Madeline Gladis
Research01 Apr 1987
Pediatric Research

Volume: 21, P: 339
Assignment of the human UDP-GalNAc:polypeptide,N-acetylgalactosaminyl transferase-type-2 gene to chromosomal region 1q42 by fluorescencein situ hybridization

Setsuo Takai
Yuji Hinoda
Kohzoh Imai
Research01 Mar 1997
Japanese Journal of Human Genetics

Volume: 42, P: 237-240

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