Nature Search

LncRNA MAPKAPK5_AS1 facilitates cell proliferation in hepatitis B virus -related hepatocellular carcinoma

The present study reveals that the hepatitis-B (HBV) antigen HBeAg found in HBV⁺HCC upregulates long non-coding RNA MAPKAPK5_AS1 (MAAS) expression in M2 macrophages by affecting its m6A modification. MAAS is transferred to HBV⁺HCC cells via exosomes, which in turn facilitates their proliferation. This is a novel role for MAAS and further elucidates the mechanism of HBeAg-induced HBV-related HCC development.

Lianyuan Tao
Deyu Li
Guoyi Yan
Research09 Mar 2022
Laboratory Investigation

Volume: 102, P: 494-504
Father-inclusive chatbot-based prenatal education during COVID-19 pandemic enhances maternal–fetal attachment in Korean primigravida women across levels of partner support

Kyungmi chung
Kyungun Jhung
Jin Young Park
ResearchOpen Access05 Aug 2025
Scientific Reports

Volume: 15, P: 1-14
Neoadjuvant ipilimumab and nivolumab in resectable cutaneous squamous cell carcinoma: a randomized phase 2 trial

Results from the randomized, noncomparative, phase 2 MATISSE trial show that ultra-short neoadjuvant therapy with ipilimumab and nivolumab can prevent surgery and radiotherapy in patients with resectable cutaneous squamous cell carcinoma, with an early decrease in total lesion glycolysis by [¹⁸F]FDG-PET/CT associated with response.

Sabine E. Breukers
Joleen J. H. Traets
Charlotte L. Zuur
ResearchOpen Access08 Oct 2025
Nature Medicine

P: 1-10
Mexican Biobank advances population and medical genomics of diverse ancestries

Nationwide genomic biobank in Mexico unravels demographic history and complex trait architecture from 6,057 individuals.

Mashaal Sohail
María J. Palma-Martínez
Andrés Moreno-Estrada
ResearchOpen Access11 Oct 2023
Nature

Volume: 622, P: 775-783
Phenotype, specificity and avidity of antitumour CD8⁺ T cells in melanoma

The authors use single-cell profiling and T cell receptor specificity screening to show how tumour antigen recognition shapes the phenotypes of CD8⁺ T cells and antitumour immune responses.

Giacomo Oliveira
Kari Stromhaug
Catherine J. Wu
Research21 Jul 2021
Nature

Volume: 596, P: 119-125
Central Nervous System Serotonin and Norepinephrine Localization in Emotional and Non-Emotional Strains in Mice

HOWARD S. SUDAK
JAMES W. MAAS
Research01 Sept 1964
Nature

Volume: 203, P: 1254-1256
Solution structure of the DNA-binding domain and model for the complex of multifunctiona hexameric arginine represser with DNA

Maria Sunnerhagen
Michael Nilges
Jannette Carey
Research01 Oct 1997
Nature Structural Biology

Volume: 4, P: 819-826
Electrification pathways for U.S. passenger vehicles

Matteo Muratori
Catherine Ledna
Kara Podkaminer
ResearchOpen Access30 Jul 2025
npj Sustainable Mobility and Transport

Volume: 2, P: 1-11
Population admixtures in medaka inferred by multiple arbitrary amplicon sequencing

Shingo Fujimoto
Hajime Yaguchi
Ryosuke Kimura
ResearchOpen Access21 Nov 2022
Scientific Reports

Volume: 12, P: 1-12
Microbial ultraviolet sunscreens

Many microorganisms produce secondary metabolites to protect their molecular constituents from the damaging effects of ultraviolet radiation. Here, Gao and Garcia-Pichel describe our current understanding of the best known examples of these microbial ultraviolet sunscreens, including their biosynthesis, regulation and potential applications.

Qunjie Gao
Ferran Garcia-Pichel
Reviews03 Oct 2011
Nature Reviews Microbiology

Volume: 9, P: 791-802
Properties of the Separated Chains of Human γ-Globulin

S. COHEN
Research19 Jan 1963
Nature

Volume: 197, P: 253-255
Joint, multifaceted genomic analysis enables diagnosis of diverse, ultra-rare monogenic presentations

Using well-calibrated statistical methods the authors jointly analyze Undiagnosed Diseases Network genomes, identifying known and novel disease genes. Software is publicly available to support future cross-cohort rare disease discovery efforts.

Shilpa Nadimpalli Kobren
Mikhail A. Moldovan
Shamil R. Sunyaev
ResearchOpen Access07 Aug 2025
Nature Communications

Volume: 16, P: 1-19
A mindful approach to controlling intrusive thoughts

S. M. Ashton
A. Sambeth
C. W. E. M. Quaedflieg
ResearchOpen Access06 Jul 2023
Scientific Reports

Volume: 13, P: 1-13
Landscape of helper and regulatory antitumour CD4⁺ T cells in melanoma

A survey of the CD4⁺ T cells in human melanomas indicates that immune evasion is mediated through direct stimulation of neoantigen-specific tumour-reactive regulatory T cells by HLA class II-positive melanoma cells.

Giacomo Oliveira
Kari Stromhaug
Catherine J. Wu
Research04 May 2022
Nature

Volume: 605, P: 532-538
Relationship of the Velocity of a Charged Particle to its Relative Biological Effectiveness

J. E. TURNER
HAL HOLLISTER
Research01 Oct 1965
Nature

Volume: 208, P: 36-37
Exploring decarbonization pathways for USA passenger and freight mobility

Rapid adoption of zero-emission vehicles with a concurrent transition to clean electricity is essential to achieve U.S. transportation decarbonization goals. Managing travel demand can ease this transition by reducing the need for clean electricity supply. @cghoehne, @nrel, #NRELMobility

Christopher Hoehne
Matteo Muratori
Ookie Ma
ResearchOpen Access30 Oct 2023
Nature Communications

Volume: 14, P: 1-15
Msx1 deficient mice exhibit cleft palate and abnormalities of craniofacial and tooth development

Ichiro Satokata
Richard Maas
Research01 Apr 1994
Nature Genetics

Volume: 6, P: 348-356
'Formins': proteins deduced from the alternative transcripts of the limb deformity gene

Richard P. Woychik
Richard L. Maas
Philip Leder
Research30 Aug 1990
Nature

Volume: 346, P: 850-853
Low angle X-ray diffraction patterns of squid retina

C. R. WORTHINGTON
S. K. WANG
C. M. FOLZER
Research12 Aug 1976
Nature

Volume: 262, P: 626-628
PAX6 gene dosage effect in a family with congenital cataracts, aniridia, anophthalmia and central nervous system defects

Tom Glaser
Lisa Jepeal
Richard L. Maas
Research01 Aug 1994
Nature Genetics

Volume: 7, P: 463-471
Mutations in the PAX3 gene causing Waardenburg syndrome type 1 and type 2

May Tassabehji
Andrew P. Read
Tom Strachan
Research01 Jan 1993
Nature Genetics

Volume: 3, P: 26-30
Optimal wavelength region for communication with extraterrestrial intelligence: λ = 1.5 mm

N. S. Kardashev
Research01 Mar 1979
Nature

Volume: 278, P: 28-30
Viral and Host Characteristics of Recent and Established HIV-1 Infections in Kisumu based on a Multiassay Approach

Newton Otecko
Seth Inzaule
Clement Zeh
ResearchOpen Access29 Nov 2016
Scientific Reports

Volume: 6, P: 1-9
A human MSX1 homeodomain missense mutation causes selective tooth agenesis

Heleni Vastardis
Nadeem Karimbux
Christine E. Seidman
Research01 Aug 1996
Nature Genetics

Volume: 13, P: 417-421
Successful Development of Chick Embryos Nourished by Yolk-Sac Perfusion with Calcium-Low Media

C. R. GRAU
N. E. WALKER
S. M. PETERS
Research19 Jan 1963
Nature

Volume: 197, P: 257-259
Extreme river flood exposes latent erosion risk

Analysis of the 2021 Meuse River flood reveals potential erosion risks due to uneven river widening and subsoil variability, highlighting challenges for river engineering and flood mitigation in a changing climate.

H. J. Barneveld
R. M. Frings
A. J. F. Hoitink
ResearchOpen Access10 Jul 2025
Nature

Volume: 644, P: 391-397
Surveillance and mapping of tribenuron-methyl-resistant weeds in wheat fields

Behrouz Khalil Tahmasebi
Eskandar Zand
Amir Sadeghpour
ResearchOpen Access19 Nov 2024
Scientific Reports

Volume: 14, P: 1-14
Response of fluorescence morphs of the mesophotic coral Euphyllia paradivisa to ultra-violet radiation

Or Ben-Zvi
Gal Eyal
Yossi Loya
ResearchOpen Access27 Mar 2019
Scientific Reports

Volume: 9, P: 1-9
Biochemical Approaches to the Problem of Protein Synthesis

J. L. SIMKIN
T. S. WORK
Research15 Jun 1957
Nature

Volume: 179, P: 1214-1219
Typical pitfalls in applications for marketing authorization of biotechnological products in Europe

Despite improvements in European regulatory standards and procedures, the occurrence of failed or problematic marketing authorization applications for biotechnological products remains common. Here, Schäffner-Dallmann and Schneider identify common regulatory concerns and consider strategies that may help prevent such issues.

Christian K. Schneider
Gabriele Schäffner-Dallmann
Reviews01 Nov 2008
Nature Reviews Drug Discovery

Volume: 7, P: 893-899
Sexually dimorphic sterility phenotypes in HoxalO-deficient mice

Ichiro Satokata
Gail Benson
Richard Maas
Research30 Mar 1995
Nature

Volume: 374, P: 460-463
Disruption of formin-encoding transcripts in two mutant limb deformity alleles

Richard L. Maas
Rolf Zeller
Philip Leder
Research30 Aug 1990
Nature

Volume: 346, P: 853-855
Systematic review and individual participant data meta-analysis of randomized controlled trials assessing mindfulness-based programs for mental health promotion

Galante et al. performed a systematic review and meta-analysis using individual participant data from randomized controlled trials evaluating mindfulness-based programs for adult mental health promotion in non-clinical settings.

Julieta Galante
Claire Friedrich
Ian R. White
ResearchOpen Access10 Jul 2023
Nature Mental Health

Volume: 1, P: 462-476
Health co-benefits of post-COVID-19 low-carbon recovery in Chinese cities

Using near-real-time daily carbon emission datasets from 48 cities in China, this paper explores post-COVID-19 during which Chinese cities experienced economic growth and reduced greenhouse gas emissions—a low-carbon recovery. Six low-carbon-recovery cities (mainly megacities) saved, on average, 1.2 times as many lives per 100,000 population than the 42 other cities.

Chenxi Lu
Yingjian Huang
Zhu Liu
Research28 Aug 2024
Nature Cities

Volume: 1, P: 695-705
Test of local realism via entangled \(\Lambda \bar{\Lambda }\) system

While Bell inequalities have been violated several times—mostly in photonic systems—their violations within particle physics experiments are less explored. Here, the BESIII Collaboration showcases Bell-violating nonlocal correlations between entangled hyperon pairs.

M. Ablikim
M. N. Achasov
J. Zu
ResearchOpen Access28 May 2025
Nature Communications

Volume: 16, P: 1-9
Asymmetric dimethylarginine and all-cause mortality: a systematic review and meta-analysis

Shaoli Zhou
Qianqian Zhu
Ziqing Hei
ResearchOpen Access15 Mar 2017
Scientific Reports

Volume: 7, P: 1-9
Juvenile idiopathic inflammatory myositis: an update on pathophysiology and clinical care

This Review provides an overview of the clinical features and subtypes, pathophysiology and management of juvenile idiopathic inflammatory myopathies, including updates to our understanding of this heterogenous group of diseases that might change clinical practice in the near future.

Charalampia Papadopoulou
Christine Chew
Lucy R. Wedderburn
Reviews15 May 2023
Nature Reviews Rheumatology

Volume: 19, P: 343-362
Death throes of massive stars

S. SOFIA
W. M. SPARKS
A. S. ENDAL
Research08 Feb 1979
Nature

Volume: 277, P: 456-457
A giant conodont with preserved muscle tissue from the Upper Ordovician of South Africa

S. E. Gabbott
R. J. Aldridge
J. N. Theron
Research27 Apr 1995
Nature

Volume: 374, P: 800-803
Summer warmth between 15,500 and 15,000 years ago enabled human repopulation of the northwest European margin

The authors use the latest radiocarbon calibration curve and new local palaeoclimatic and palaeoenvironmental records from Britain to show that humans repopulated the northwest European margin between 15,500 and 15,000 years ago, supported by local summer warmth occurring earlier than previously thought.

I. P. Matthews
A. P. Palmer
J. Burton
ResearchOpen Access02 Jul 2025
Nature Ecology & Evolution

Volume: 9, P: 1179-1192
A genome-wide association study identifies CDHR3 as a susceptibility locus for early childhood asthma with severe exacerbations

Klaus Bønnelykke and colleagues identify a common variant in CDHR3 associated with early childhood asthma with severe exacerbations. CDHR3 encodes a cell adhesion protein expressed at high levels in airway epithelium, suggesting a role for altered epithelial integrity in asthma pathogenesis.

Klaus Bønnelykke
Patrick Sleiman
Hans Bisgaard
Research17 Nov 2013
Nature Genetics

Volume: 46, P: 51-55
Cerebral lateralisation effects in visual half-field experiments

CURTIS HARDYCK
OVID J. L. TZENG
WILLIAM S-Y. WANG
Research20 Oct 1977
Nature

Volume: 269, P: 705-707
How can general dental practitioners help in the management of sleep apnoea?

David Parmenter
Brian J. Millar
ResearchOpen Access14 Apr 2023
British Dental Journal

Volume: 234, P: 505-509
Structure revision of scytonemin imine and its relationship to scytonemin chromism and cyanobacterial adaptability

Garrett E. Larson
Tanzil Mahmud
Christopher S. Jeffrey
ResearchOpen Access15 Jul 2025
Scientific Reports

Volume: 15, P: 1-12
Acute Effect of a Glucocorticoid on Normal Human Sleep

J. CHRISTIAN GILLIN
LEONARD S. JACOBS
FREDERICK SNYDER
Research16 Jun 1972
Nature

Volume: 237, P: 398-399
Localization and Release of Glutamic Acid in Relation to the Hippocampal Mossy Fibre Pathway

I. L. CRAWFORD
J. D. CONNOR
Research17 Aug 1973
Nature

Volume: 244, P: 442-443
Quasar enhanced

S. K. ALURKAR
A. K. SHARMA
R. V. BHONSLE
Research16 Mar 1989
Nature

Volume: 338, P: 211-212
One sixth of Amazonian tree diversity is dependent on river floodplains

Analysing >1,700 inventory plots from the Amazon Tree Diversity Network, the authors show that the majority of Amazon tree species can occupy floodplains and that patterns of species turnover are closely linked to regional flood patterns.

John Ethan Householder
Florian Wittmann
Hans ter Steege
ResearchOpen Access11 Mar 2024
Nature Ecology & Evolution

Volume: 8, P: 901-911
Stress-resilience impacts psychological wellbeing as evidenced by brain–gut microbiome interactions

The authors evaluated and integrated compositional and functional microbiota data using fecal samples taken from healthy individuals and multimodal neuroimaging.

Eric An
Desiree R. Delgadillo
Arpana Gupta
Research21 Jun 2024
Nature Mental Health

Volume: 2, P: 935-950
Consistent patterns of common species across tropical tree communities

Inventory data from more than 1 million trees across African, Amazonian and Southeast Asian tropical forests suggests that, despite their high diversity, just 1,053 species, representing a consistent ~2.2% of tropical tree species in each region, constitute half of Earth’s 800 billion tropical trees.

Declan L. M. Cooper
Simon L. Lewis
Stanford Zent
ResearchOpen Access10 Jan 2024
Nature

Volume: 625, P: 728-734

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