Nature Search

Pathology-oriented multiplexing enables integrative disease mapping

Pathology-oriented multiplexing (PathoPlex) represents a framework for widespread access to multiplexed imaging and computational image analysis of clinical specimens at a relatively high throughput and subcellular resolution.

Malte Kuehl
Yusuke Okabayashi
Victor G. Puelles
ResearchOpen Access18 Jul 2025
Nature

Volume: 644, P: 516-526
Dual stream graph augmented transformer model integrating BERT and GNNs for context aware fake news detection

Hejamadi Rama Moorthy
N. J. Avinash
Lubna A Gabralla
ResearchOpen Access14 Jul 2025
Scientific Reports

Volume: 15, P: 1-25
Image prediction of disease progression for osteoarthritis by style-based manifold extrapolation

Predicting disease progression is an important medical problem, but it can be challenging for end-to-end machine learning approaches. Han and colleagues demonstrate that generative models can work together with medical experts to jointly predict the progression of a disease, osteoarthritis.

Tianyu Han
Jakob Nikolas Kather
Daniel Truhn
Research16 Nov 2022
Nature Machine Intelligence

Volume: 4, P: 1029-1039
Aspartate signalling drives lung metastasis via alternative translation

Aspartate in the tumour environment activates the N-methyl-d-aspartate receptor in cancer cells to induce cellular programmes that increase the aggressiveness of metastasis.

Ginevra Doglioni
Juan Fernández-García
Sarah-Maria Fendt
Research01 Jan 2025
Nature

Volume: 638, P: 244-250
Sources of acidification in Central Europe estimated from elemental budgets in small basins

Tomas Paces
Research02 May 1985
Nature

Volume: 315, P: 31-36
Probing the limits and capabilities of diffusion models for the anatomic editing of digital twins

Karim Kadry
Shreya Gupta
Elazer R. Edelman
ResearchOpen Access05 Dec 2024
npj Digital Medicine

Volume: 7, P: 1-12
Multifactorial inheritance of neural tube defects: localization of the major gene and recognition of modifiers in ct mutant mice

Paul E. Neumann
Wayne N. Frankel
Merton Bernfield
Research01 Apr 1994
Nature Genetics

Volume: 6, P: 357-362
Enzymatic Synthesis of Adrenaline in Mammalian Brain

ROLAND D. CIARANELLO
REBECCA E. BARCHAS
JACK D. BARCHAS
Research25 Jan 1969
Nature

Volume: 221, P: 368-369
PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

PHDGH heterogeneity in primary tumours could be a sign of tumour aggressiveness.

Matteo Rossi
Patricia Altea-Manzano
Sarah-Maria Fendt
Research18 May 2022
Nature

Volume: 605, P: 747-753
A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression

Verginadis et al. show that ATF4 regulates Col1a1 expression and collagen biosynthesis in perivascular cancer-associated fibroblasts, thereby supporting angiogenesis and progression in melanoma and pancreatic cancer.

Ioannis I. Verginadis
Harris Avgousti
Constantinos Koumenis
ResearchOpen Access02 Jun 2022
Nature Cell Biology

Volume: 24, P: 940-953
“You’re telling us to go first?!” COVID-19 pandemic and vaccination experiences among Aboriginal adults in Western Australia

Samantha J. Carlson
Carla Puca
Christopher C. Blyth
ResearchOpen Access27 Jan 2025
Humanities and Social Sciences Communications

Volume: 12, P: 1-10
Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

Cytoplasmic polyadenylated transcripts have been poorly characterized, particularly in cancer. Here the authors identify a lineage-specific requirement of the cytoplasmic polyadenylation binding protein 4 (CPEB4) in malignant melanoma and show that it controls melanoma drivers MITF and RAB27A.

Eva Pérez-Guijarro
Panagiotis Karras
María S. Soengas
ResearchOpen Access18 Nov 2016
Nature Communications

Volume: 7, P: 1-17
An Open Source Python Library for Anonymizing Sensitive Data

Judith Sáinz-Pardo Díaz
Álvaro López García
ResearchOpen Access26 Nov 2024
Scientific Data

Volume: 11, P: 1-14
Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

Hundreds of mRNA binding proteins (mRBPs) have been described in mammalian cells. Here, the authors identify RBPs differentially regulated in melanoma, and show the RBP CELF1 controlling a distinct set of protumorigenic factors.

Metehan Cifdaloz
Lisa Osterloh
María S. Soengas
ResearchOpen Access21 Dec 2017
Nature Communications

Volume: 8, P: 1-18
Attosecond metrology of the two-dimensional charge distribution in molecules

Attosecond interferometry measurements of photoionization delays in planar carbon-based molecules can provide information on the dimension and shape of the two-dimensional hole generated in the process.

V. Loriot
A. Boyer
F. Lépine
Research23 Feb 2024
Nature Physics

Volume: 20, P: 765-769
Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

Crescentic rapidly progressive glomerulonephritis is a severe form of glomerula disease characterized by podocyte proliferation and migration. Here Henique et al. demonstrate that inhibition of miRNA-92a prevents kidney failure by promoting the expression of CDK inhibitor p57^Kip2 that regulates podocyte cell cycle.

Carole Henique
Guillaume Bollée
Pierre-Louis Tharaux
ResearchOpen Access28 Nov 2017
Nature Communications

Volume: 8, P: 1-15
A versatile high-average-power ultrafast infrared driver tailored for high-harmonic generation and vibrational spectroscopy

Nicolas Thiré
Gourab Chatterjee
Nicolas Forget
ResearchOpen Access01 Nov 2023
Scientific Reports

Volume: 13, P: 1-6
Hypovitaminosis D in pregnancy in the Mediterranean region: a systematic review

S Karras
S A Paschou
D G Goulis
Reviews02 Mar 2016
European Journal of Clinical Nutrition

Volume: 70, P: 979-986
Fas ligation on macrophages enhances IL-1R1–Toll-like receptor 4 signaling and promotes chronic inflammation

Yingyu Ma
Hongtao Liu
Richard M Pope
Research07 Mar 2004
Nature Immunology

Volume: 5, P: 380-387
Deep learning for synthetic microstructure generation in a materials-by-design framework for heterogeneous energetic materials

Sehyun Chun
Sidhartha Roy
Stephen S. Baek
ResearchOpen Access06 Aug 2020
Scientific Reports

Volume: 10, P: 1-15
Impact of religious fasting on metabolic and hematological profile in both dyslipidemic and non-dyslipidemic fasters

Andreas S. Papazoglou
Dimitrios V. Moysidis
Georgios Sianos
Research01 Dec 2021
European Journal of Clinical Nutrition

Volume: 76, P: 891-898
Vitamin D status during pregnancy: time for a more unified approach beyond borders?

S N Karras
P Anagnostis
D G Goulis
Reviews18 Mar 2015
European Journal of Clinical Nutrition

Volume: 69, P: 874-877
Causes of subcutaneous emphysema following dental procedures: a systematic review of cases 1993-2020

Adam Jones
Sami Stagnell
Richard Moore
Research22 Oct 2021
British Dental Journal

Volume: 231, P: 493-500
Genomic characterization of the human trkC gene

Natalia Ichaso
Raquel E Rodriguez
Rogelio Gonzalez-Sarmiento
Research09 Oct 1998
Oncogene

Volume: 17, P: 1871-1875
The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells

M Sprangers
N Feldhahn
M Müschen
Research27 Mar 2006
Oncogene

Volume: 25, P: 5056-5062
A clofarabine-based bridging regimen in patients with relapsed ALL and persistent minimal residual disease (MRD)

N Gossai
M R Verneris
M J Burke
Research09 Dec 2013
Bone Marrow Transplantation

Volume: 49, P: 440-442
Maternal vitamin D status during pregnancy: the Mediterranean reality

S N Karras
P Anagnostis
D G Goulis
Reviews14 May 2014
European Journal of Clinical Nutrition

Volume: 68, P: 864-869
Cell cycle effects of IL-10 on malignant B-1 cells

S Yen Chong
Y-C Lin
E Raveche
Research30 Aug 2001
Genes & Immunity

Volume: 2, P: 239-247
Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

Here, Zuber et al., on behalf of the French Study Group for aHUS/C3G, discuss the role of eculizumab in the treatment of atypical haemolytic uraemic syndrome (aHUS). They review data from case reports and preliminary data from prospective trials, present their opinions, and describe issues that require further study. In addition, they discuss the potential use of eculizumab in C3 glomerulopathies.

Julien Zuber
Fadi Fakhouri
Véronique Frémeaux-Bacchi
Reviews02 Oct 2012
Nature Reviews Nephrology

Volume: 8, P: 643-657
Ultraviolet radiation and effects on humans: the paradigm of maternal vitamin D production during pregnancy

A Anastasiou
S N Karras
D G Goulis
Reviews28 Sept 2016
European Journal of Clinical Nutrition

Volume: 71, P: 1268-1272
Health benefits and consequences of the Eastern Orthodox fasting in monks of Mount Athos: a cross-sectional study

S N Karras
A Persynaki
D P Naughton
Research22 Mar 2017
European Journal of Clinical Nutrition

Volume: 71, P: 743-749
Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: The SCALE Maintenance randomized study

T A Wadden
P Hollander
L Aronne
Research01 Jul 2013
International Journal of Obesity

Volume: 37, P: 1443-1451
Wwox–Brca1 interaction: role in DNA repair pathway choice

M S Schrock
B Batar
K Huebner
ResearchOpen Access21 Nov 2016
Oncogene

Volume: 36, P: 2215-2227

Search

Pathology-oriented multiplexing enables integrative disease mapping

Dual stream graph augmented transformer model integrating BERT and GNNs for context aware fake news detection

Image prediction of disease progression for osteoarthritis by style-based manifold extrapolation

Aspartate signalling drives lung metastasis via alternative translation

Sources of acidification in Central Europe estimated from elemental budgets in small basins

Probing the limits and capabilities of diffusion models for the anatomic editing of digital twins

Multifactorial inheritance of neural tube defects: localization of the major gene and recognition of modifiers in ct mutant mice

Enzymatic Synthesis of Adrenaline in Mammalian Brain

PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

A stromal Integrated Stress Response activates perivascular cancer-associated fibroblasts to drive angiogenesis and tumour progression

“You’re telling us to go first?!” COVID-19 pandemic and vaccination experiences among Aboriginal adults in Western Australia

Lineage-specific roles of the cytoplasmic polyadenylation factor CPEB4 in the regulation of melanoma drivers

An Open Source Python Library for Anonymizing Sensitive Data

Systems analysis identifies melanoma-enriched pro-oncogenic networks controlled by the RNA binding protein CELF1

Attosecond metrology of the two-dimensional charge distribution in molecules

Genetic and pharmacological inhibition of microRNA-92a maintains podocyte cell cycle quiescence and limits crescentic glomerulonephritis

A versatile high-average-power ultrafast infrared driver tailored for high-harmonic generation and vibrational spectroscopy

Hypovitaminosis D in pregnancy in the Mediterranean region: a systematic review

Fas ligation on macrophages enhances IL-1R1–Toll-like receptor 4 signaling and promotes chronic inflammation

Deep learning for synthetic microstructure generation in a materials-by-design framework for heterogeneous energetic materials

Impact of religious fasting on metabolic and hematological profile in both dyslipidemic and non-dyslipidemic fasters

Vitamin D status during pregnancy: time for a more unified approach beyond borders?

Causes of subcutaneous emphysema following dental procedures: a systematic review of cases 1993-2020

Genomic characterization of the human trkC gene

The SRC family kinase LYN redirects B cell receptor signaling in human SLP65-deficient B cell lymphoma cells

A clofarabine-based bridging regimen in patients with relapsed ALL and persistent minimal residual disease (MRD)

Maternal vitamin D status during pregnancy: the Mediterranean reality

Cell cycle effects of IL-10 on malignant B-1 cells

Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies

Ultraviolet radiation and effects on humans: the paradigm of maternal vitamin D production during pregnancy

Health benefits and consequences of the Eastern Orthodox fasting in monks of Mount Athos: a cross-sectional study

Weight maintenance and additional weight loss with liraglutide after low-calorie-diet-induced weight loss: The SCALE Maintenance randomized study

Wwox–Brca1 interaction: role in DNA repair pathway choice

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