Keller and colleagues report a method for differentiation and isolation of one of the earliest human cardiac progenitors from human ES cells. They show that these cardiac progenitors can form cardiac, endothelial and vascular smooth muscle in vivo and in vitro, and can form a population of contracting cardiomyocytes when plated in culture.
- Lei Yang
- Mark H. Soonpaa
- Gordon M. Keller