Clinical translation of cell products is impeded by the lack of clinically predictive potency assays. Here, the authors report a microfluidic system to evaluate patient-derived cells used in a clinical trial for osteoarthritis pain, and use the results and patient-matched clinical data to build prediction models, showing improved clinical prediction and higher correlative power with pain scores compared to 2D culture.
- Rebecca S. Schneider
- Elisa B. Nieves
- Andrés J. García
