Nature Search

Natural gene therapy and the Darwinian legacy

Hagop Youssoufian
News & Views01 Jul 1996
Nature Genetics

Volume: 13, P: 255-256
Der Schädel des eiszeitlichen Menschen von Le Moustier in neuer Zusammensetzung

A. S. W.
Books & Arts07 Nov 1925
Nature

Volume: 116, P: 672
Geology and Early Man

H. B. S. COOKE
C. VAN RIET LOWE
L. H. WELLS
Research11 Jan 1941
Nature

Volume: 147, P: 45-49
Model calculations of the relative effects of CFCs and their replacements on stratospheric ozone

Donald A. Fisher
Charles H. Hales
Frode Stordal
Research05 Apr 1990
Nature

Volume: 344, P: 508-512
A cavity-containing mutant of T4 lysozyme is stabilized by buried benzene

A. E. Eriksson
W. A. Baase
B. W. Matthews
Research23 Jan 1992
Nature

Volume: 355, P: 371-373
Antennal receptor response to sex pheromone mimics in the American cockroach

HIROSHI WASHIO
CHIKAO NISHINO
WILLIAM S. BOWERS
Research05 Aug 1976
Nature

Volume: 262, P: 487-489
Genomic signatures of human and animal disease in the zoonotic pathogen Streptococcus suis

The bacterium Streptococcus suiscauses respiratory tract infections in pigs and meningitis in humans. Here, the authors show that human disease isolates are limited to a single virulent population and find no consistent genomic differences between pig and human isolates.

Lucy A. Weinert
Roy R. Chaudhuri
Vanessa Terra
ResearchOpen Access31 Mar 2015
Nature Communications

Volume: 6, P: 1-10
Removal of promoter CpG methylation by epigenome editing reverses HBG silencing

DNA methylation is a critical component for repression of fetal haemoglobin in adult blood cells. Removing DNA methylation from the fetal haemoglobin promoter effectively upregulates the gene, opening avenues for the treatment of blood disorders.

Henry W. Bell
Ruopeng Feng
Merlin Crossley
ResearchOpen Access27 Jul 2025
Nature Communications

Volume: 16, P: 1-16
Spatial fluctuations in barrier height at the graphene–silicon carbide Schottky junction

The interfacing of graphene with a semiconductor creates a Schottky junction, with the formation of ripples on graphene being common. Here, the authors experimentally quantify spatial fluctuations in Schottky barrier height and the effect that ripples have.

S. Rajput
M.X. Chen
L. Li
Research21 Nov 2013
Nature Communications

Volume: 4, P: 1-7
hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation

Lei Li
Carolyn A Peterson
Randy J Legerski
Research15 Mar 1999
Oncogene

Volume: 18, P: 1689-1699
Ostriches recognise their own eggs and discard others

BRIAN C. R. BERTRAM
Research17 May 1979
Nature

Volume: 279, P: 233-234
Yeast genes and human disease

Douglas E. Bassett
Mark S. Boguski
Philip Hieter
Research15 Feb 1996
Nature

Volume: 379, P: 589-590
Regulation of progression through the Gl phase of the cell cycle by the rum1⁺ gene

Sergio Moreno
Paul Nurse
Research20 Jan 1994
Nature

Volume: 367, P: 236-242
Translocator protein is a marker of activated microglia in rodent models but not human neurodegenerative diseases

TSPO PET imaging is widely used to quantify microglial activation. Here, the authors show that TSPO expression increases in activated rodent but not human microglia, implying that in humans TSPO informs on microglial density rather than activation status.

Erik Nutma
Nurun Fancy
David R. Owen
ResearchOpen Access28 Aug 2023
Nature Communications

Volume: 14, P: 1-25
Bile salt hydrolase catalyses formation of amine-conjugated bile acids

We find that bile salt hydrolase N-acyltransferase activity can form bacterial bile acid amidates that are positively correlated with the colonization of gut bacteria that assist in the regulation of the bile acid metabolic network.

Bipin Rimal
Stephanie L. Collins
Andrew D. Patterson
ResearchOpen Access07 Feb 2024
Nature

Volume: 626, P: 859-863
Biomimetic assemblage of nucleobase 5-fluorouracil into nano-size three-dimensional particles

Arun Chauhan
Swaleha Zubair
Mohammad Owais
ResearchOpen Access04 Aug 2011
Nature Precedings

P: 1
Structure and mechanism of copper, zinc superoxide dismutase

John A. Tainer
Elizabeth D. Getzoff
David C. Richardson
Research17 Nov 1983
Nature

Volume: 306, P: 284-287
Theoretical evidence for a new ultra-high-pressure phase of SiO²

Key Taeck Park
Kiyoyuki Terakura
Yoshito Matsui
Research15 Dec 1988
Nature

Volume: 336, P: 670-672
Electrostatic recognition between superoxide and copper, zinc superoxide dismutase

Elizabeth D. Getzoff
John A. Tainer
David C. Richardson
Research17 Nov 1983
Nature

Volume: 306, P: 287-290
Otitic hydrocephalus and papilloedema—re-evaluating a treatment paradigm

Tiffany A. Chen
Marguerite C. Weinert
Ryan Gise
Research19 Nov 2024
Eye

Volume: 39, P: 741-747
Development of a long noncoding RNA-based machine learning model to predict COVID-19 in-hospital mortality

Identifying biomarkers associated with risk of severe COVID-19 disease could inform clinical management. Here, the authors identify a long noncoding RNA associated with severe disease using data from three European countries, and validate their finding in data from Canada.

Yvan Devaux
Lu Zhang
Hüseyin Firat
ResearchOpen Access20 May 2024
Nature Communications

Volume: 15, P: 1-12
Serial millisecond crystallography for routine room-temperature structure determination at synchrotrons

Serial crystallography was developed for protein crystal data collection with X-ray free-electron lasers. Here the authors present several examples which show that serial crystallography using high-viscosity injectors can also be routinely employed for room-temperature data collection at synchrotrons.

Tobias Weinert
Natacha Olieric
Jörg Standfuss
ResearchOpen Access14 Sept 2017
Nature Communications

Volume: 8, P: 1-11
Tuning Dirac states by strain in the topological insulator Bi₂Se₃

Bismuth selenide is a prototypical 3D topological insulator; its electronic spectrum features a Dirac cone populated by surface states. Now, it is experimentally and numerically shown that a bandgap forms beyond a certain critical compressive strain, destroying the surface states.

Y. Liu
Y. Y. Li
L. Li
Research16 Mar 2014
Nature Physics

Volume: 10, P: 294-299
Monstrous outrage

W. R. BOURNE
S. HOWE
Correspondence23 Sept 1982
Nature

Volume: 299, P: 294
The global distribution and spread of the mobilized colistin resistance gene mcr-1

The recent plasmid-mediated spread of the mobilized colistin resistance gene mcr-1 poses a significant public health threat, requiring worldwide monitoring and surveillance. Here, Wang et al. compile and analyze a data set of 457 mcr-1-positive sequenced isolates to investigate the origin and global distribution of mcr-1.

Ruobing Wang
Lucy van Dorp
Francois Balloux
ResearchOpen Access21 Mar 2018
Nature Communications

Volume: 9, P: 1-9
Quality over quantity: unraveling the contributions to cytoplasmic incompatibility caused by two coinfecting Cardinium symbionts

Matthew R. Doremus
Corinne M. Stouthamer
Martha S. Hunter
Research05 Feb 2022
Heredity

Volume: 128, P: 187-195
P53 and radiation responses

Peiwen Fei
Wafik S El-Deiry
Reviews28 Aug 2003
Oncogene

Volume: 22, P: 5774-5783
Evidence for light-by-light scattering in heavy-ion collisions with the ATLAS detector at the LHC

Quantum electrodynamics predicts a rare process in which light is scattered by light. The ATLAS Collaboration reports signs of this elusive effect in the collisions of ultra-relativistic lead ions.

M. Aaboud
G. Aad
L. Zwalinski
ResearchOpen Access14 Aug 2017
Nature Physics

Volume: 13, P: 852-858
Effect of time to operative repair within twenty-four hours on visual acuity outcomes for open globe injuries

Kevin G. Makhoul
Racquel A. Bitar
Alice C. Lorch
Research21 Dec 2022
Eye

Volume: 37, P: 2351-2355
SUCLA2 mutations cause global protein succinylation contributing to the pathomechanism of a hereditary mitochondrial disease

The pathomechanism of succinyl-CoA ligase (SCL) deficiency, a hereditary mitochondrial disease, is not fully understood. Here, the authors show that increased succinyl-CoA levels contribute to SCL pathology by causing global protein hyper-succinylation.

Philipp Gut
Sanna Matilainen
Eric Verdin
ResearchOpen Access23 Nov 2020
Nature Communications

Volume: 11, P: 1-14
Mammalian Chk2 is a downstream effector of the ATM-dependent DNA damage checkpoint pathway

Priya Chaturvedi
Wai K Eng
Bin-Bing S Zhou
Research30 Jul 1999
Oncogene

Volume: 18, P: 4047-4054
Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations

Mutations in the costimulatory molecule CTLA-4 in six families are associated with immune dysregulation.

Desirée Schubert
Claudia Bode
Bodo Grimbacher
Research20 Oct 2014
Nature Medicine

Volume: 20, P: 1410-1416
104 NEW ENGLAND REGIONAL INFANT CARDIAC PROGRAM (NERICP) Effects on Care Delivery

Donald C Fyler
Lucy P Buckley
Alexander S Nadas
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 381
105 EFFECT OF DC COUNTERSHOCK (CS) ON THE MYOCARDIUM OF THE NEWBORN PIGLET

David M Gaba
Barry L Zaret
Norman S Talner
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 381
103 URINARY EXCRETION OF PROSTAGLANDIN E FOLLOWING THE ADMINISTRATION OF FUROSEMIDE AND INDOMETHACIN TO SICK LOW BIRTHUEIGHT INFANTS

Zvi Friedman
Laurence M Demers
M Jeffrey Maisels
Research01 Apr 1978
Pediatric Research

Volume: 12, P: 381
Out-of-Africa migration and Neolithic coexpansion of Mycobacterium tuberculosis with modern humans

Iñaki Comas and colleagues report whole-genome sequencing and analysis of 259 Mycobacterium tuberculosis complex strains, providing a survey of global diversity and facilitating evolutionary analyses. Their phylogeographic analysis suggests the emergence of M. tuberculosis complex strains about 70,000 years ago in Africa, with expansion correlated with increased human population density during the Neolithic Demographic Transition.

Iñaki Comas
Mireia Coscolla
Sebastien Gagneux
Research01 Sept 2013
Nature Genetics

Volume: 45, P: 1176-1182
The spindle checkpoint: structural insights into dynamic signalling

Andrea Musacchio
Kevin G. Hardwick
Reviews01 Oct 2002
Nature Reviews Molecular Cell Biology

Volume: 3, P: 731-741
Comparative population genomics in animals uncovers the determinants of genetic diversity

Genome-wide DNA polymorphism analysis across 76 animal species reveals a strong effect of ecological strategies, and particularly parental investment, on species levels of genetic diversity.

J. Romiguier
P. Gayral
N. Galtier
Research20 Aug 2014
Nature

Volume: 515, P: 261-263
Enhanced sensitivity of the LIGO gravitational wave detector by using squeezed states of light

Squeezed states of light have been experimentally demonstrated to improve the performance of the Laser Interferometer Gravitational-wave Observatory (LIGO) in astrophysically relevant frequency regions. This enhanced performance may help to reach the sensitivity required for detecting gravitational waves.

J. Aasi
J. Abadie
J. Zweizig
Research21 Jul 2013
Nature Photonics

Volume: 7, P: 613-619
UVB induced cell cycle checkpoints in an early stage human melanoma line, WM35

T Petrocelli
J Slingerland
Research14 Sept 2000
Oncogene

Volume: 19, P: 4480-4490
Enforced CDK4 expression in a hematopoietic cell line confers resistance to the G1 arrest induced by ionizing radiation

Michael F Reed
Vivian F Liu
Mark E Ewen
Research09 Dec 1998
Oncogene

Volume: 17, P: 2961-2971
Single and multi-objective real-time optimisation of an industrial injection moulding process via a Bayesian adaptive design of experiment approach

Mandana Kariminejad
David Tormey
Marion McAfee
ResearchOpen Access30 Nov 2024
Scientific Reports

Volume: 14, P: 1-19
A gravitational-wave standard siren measurement of the Hubble constant

The astronomical event GW170817, detected in gravitational and electromagnetic waves, is used to determine the expansion rate of the Universe, which is consistent with and independent of existing measurements.

B. P. Abbott
R. Abbott
M. Serra-Ricart
Research16 Oct 2017
Nature

Volume: 551, P: 85-88
The growing landscape of lysine acetylation links metabolism and cell signalling

Recent technical advances are expanding our understanding of how lysine acetylation, as well as other metabolite-sensitive acylations, regulates various cellular processes. Emerging findings point to new functions for different acylations and deacylating enzymes, and clarify the intricate link between lysine acetylation and cellular metabolism.

Chunaram Choudhary
Brian T. Weinert
Matthias Mann
Reviews23 Jul 2014
Nature Reviews Molecular Cell Biology

Volume: 15, P: 536-550
Mechanistically comparing reproductive manipulations caused by selfish chromosomes and bacterial symbionts

Elena Dalla Benetta
Omar S. Akbari
Patrick M. Ferree
Reviews01 Mar 2021
Heredity

Volume: 126, P: 707-716
A gravitational wave observatory operating beyond the quantum shot-noise limit

‘Squeezed light’ enables quantum noise in one aspect of light to be reduced by increasing the noise, or more accurately the quantum uncertainty, of a complementary aspect. This has now been used to push the detectors at the heart of the GEO600 gravitational wave observatory to unprecedented levels of sensitivity.

J. Abadie
B. P. Abbott
J. Zweizig
Research11 Sept 2011
Nature Physics

Volume: 7, P: 962-965
An upper limit on the stochastic gravitational-wave background of cosmological origin

A stochastic background of gravitational waves is expected to arise from a superposition of a large number of unresolved gravitational-wave sources and should carry unique signatures from the earliest epochs of the Universe. Limits on the amplitude of the stochastic gravitational-wave background are now reported using the data from a two-year science run of the Laser Interferometer Gravitational-wave Observatory. These limits rule out certain models of early Universe evolution.

B. P. Abbott
R. Abbott
J. Zweizig
Research20 Aug 2009
Nature

Volume: 460, P: 990-994
The effects of nutrition education on professionals' practice and on the nutrition of aged residents in dementia wards

M H Suominen
S M Kivisto
K H Pitkala
Research24 Jan 2007
European Journal of Clinical Nutrition

Volume: 61, P: 1226-1232
The role of ATM in DNA damage responses and cancer

Christine E Canman
Dae-Sik Lim
Reviews12 Jan 1999
Oncogene

Volume: 17, P: 3301-3308
Atypical chemokine receptor ACKR2-V41A has decreased CCL2 binding, scavenging, and activation, supporting sustained inflammation and increased Alzheimer’s disease risk

Josue D. Gonzalez Murcia
Allen Weinert
K. Scott Weber
ResearchOpen Access15 May 2020
Scientific Reports

Volume: 10, P: 1-12

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