Dendritic cells alternate between fast and slow migratory behaviours, however in the absence of a component of the antigen processing machinery, migration is uniform and fast. Chabaudet al. now show that slow migration results from the relocalisation of myosin II to the cell front where it promotes antigen capture.
- Mélanie Chabaud
- Mélina L. Heuzé
- Ana-Maria Lennon-Duménil