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Advanced filters: Author: Sabina Adhikary Clear advanced filters

TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers

In a first-in-human phase 1 trial of patients with HPV-associated metastatic epithelial cancers, T cells targeting HPV-16 E7 were well tolerated, with one observed dose-limiting toxicity, and elicited objective clinical responses in 6 of 12 treated patients.

Nisha B. Nagarsheth
Scott M. Norberg
Christian S. Hinrichs
Research08 Feb 2021
Nature Medicine

Volume: 27, P: 419-425
Three-year analysis of adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3

Bijal D. Shah
Ryan D. Cassaday
Olalekan O. Oluwole
ResearchOpen Access19 Mar 2025
Leukemia

Volume: 39, P: 1058-1068

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TCR-engineered T cells targeting E7 for patients with metastatic HPV-associated epithelial cancers

Three-year analysis of adult patients with relapsed or refractory B-cell acute lymphoblastic leukemia treated with brexucabtagene autoleucel in ZUMA-3

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